Natco Pharma QC Manager Interview Questions and Answers

My daily activities as an In-Process Quality Assurance (IPQA) officer involve monitoring and ensuring quality standards are met during production.

• Conducting in-process inspections to verify product quality

• Reviewing production documentation for accuracy and compliance

• Identifying and addressing any quality issues or deviations

• Collaborating with production team to implement corrective actions

• Maintaining records of inspect

Detectors in HPLC include UV-Vis, fluorescence, refractive index, and mass spectrometry.

• UV-Vis detector measures absorbance of UV or visible light by the analyte.

• Fluorescence detector measures fluorescence emitted by the analyte when excited by light.

• Refractive index detector measures changes in refractive index of the eluent.

• Mass spectrometry detector measures mass-to-charge ratio of ions produced from analyte.

UV and FTIR principles are analytical techniques used for identifying and analyzing chemical compounds based on their absorption of ultraviolet-visible light and infrared radiation, respectively.

• UV spectroscopy involves measuring the absorption of UV or visible light by a sample to determine its concentration or purity.

• FTIR spectroscopy measures the absorption of infrared radiation by a sample to identify functional gr...read more

Precautions for UV analysis include wearing protective gear, calibrating equipment, and avoiding contamination.

• Wear appropriate protective gear such as gloves, goggles, and lab coat to prevent exposure to UV radiation.

• Calibrate UV equipment regularly to ensure accurate readings.

• Avoid contamination by cleaning all surfaces and equipment thoroughly before starting the analysis.

• Handle UV-sensitive samples carefully to pre...read more

KBr is used in IR analysis to prepare samples for analysis by creating a transparent pellet.

• KBr is used as a diluent to mix with the sample being analyzed

• It helps to create a transparent pellet which allows for accurate analysis of the sample

• KBr has a wide transmission range in the infrared spectrum

• It is chemically inert and does not interfere with the sample being analyzed