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Dr. Reddy's Research Scientist Interview Questions, Process, and Tips
Top Dr. Reddy's Research Scientist Interview Questions and Answers
- Q1. 1)How much percent of buffer used in mobile phase 2) Why we use sls in disso and how much %Allowed
- Q2. What is the criteria/limit for impuritiy recovery
- Q3. How to decide the sink condition
Dr. Reddy's Research Scientist Interview Experiences
2 interviews found
Selected
I applied via Referral and was interviewed before Jul 2022. There were 3 interview rounds.
(1 Question)
- Q1. Method development and validation related. Quality review and specifications
(1 Question)
- Q1. Method development and performance related
Interview Preparation Tips
Interview Questionnaire
5 Questions
- Q1. 1)How much percent of buffer used in mobile phase 2) Why we use sls in disso and how much %Allowed
- Ans.
The percentage of buffer used in mobile phase and the use of SLS in disso and its allowed percentage.
The percentage of buffer used in the mobile phase depends on the specific experiment and the desired separation of compounds.
Buffer is used in the mobile phase to maintain the pH and ionic strength, which can affect the separation and stability of analytes.
The percentage of buffer can range from 5% to 50% or more, depen...
- Q2. How to decide the sink condition
- Ans.
The sink condition is decided based on various factors such as the purpose of the sink, the type of research being conducted, and the desired outcome.
Consider the purpose of the sink - Is it for disposal, storage, or analysis of substances?
Evaluate the type of research being conducted - Does it involve chemical reactions, biological samples, or physical measurements?
Assess the desired outcome - Are you looking for pres...
- Q3. What is the criteria/limit for impuritiy recovery
- Ans.
The criteria/limit for impurity recovery depends on the specific research study and the desired purity level.
The criteria for impurity recovery may include the maximum allowable impurity concentration or percentage.
The limit for impurity recovery can be determined based on regulatory guidelines or industry standards.
The desired purity level may vary depending on the application or intended use of the research findings.
...
- Q4. What is mass balance and limit of it
- Ans.
Mass balance is a principle used in various scientific disciplines to account for the mass of substances in a system.
Mass balance is based on the principle of conservation of mass, which states that mass cannot be created or destroyed, only transferred or transformed.
It involves tracking the inputs, outputs, and accumulation of mass within a system.
Mass balance equations are commonly used in environmental science, chem...
- Q5. Importance of RF values
- Ans.
RF values are important in chromatography to identify and separate compounds.
RF value is the ratio of the distance traveled by a compound to the distance traveled by the solvent front in chromatography.
It helps in identifying and separating compounds based on their polarity and solubility.
RF values can be used to compare compounds and determine their purity.
For example, in thin-layer chromatography, RF values are used ...
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Research Scientist Interview Questions & Answers
Alembic Pharmaceuticals
Anonymous
posted on 23 Sep 2021
I applied via Company Website and was interviewed before Sep 2020. There were 3 interview rounds.
Interview Questionnaire
2 Questions
- Q1. What is the roll of legand in Suzuki coupling reaction?
- Ans.
The role of a ligand in Suzuki coupling reaction is to facilitate the formation of a stable complex between the catalyst and the reactants.
A ligand coordinates with the catalyst metal center, enhancing its reactivity and selectivity.
It helps in stabilizing the transition state and lowering the activation energy of the reaction.
Different ligands can influence the reaction rate and product distribution.
Common ligands use...
- Q2. Which name reaction mechanism you know in best manner?
- Ans.
I am well-versed with the mechanism of the Grignard reaction.
Grignard reaction involves the addition of an organomagnesium halide to a carbonyl compound.
It is a nucleophilic addition reaction.
The reaction is highly useful in organic synthesis, especially for the formation of carbon-carbon bonds.
Examples include the synthesis of alcohols, carboxylic acids, and ketones.
The reaction is named after French chemist Victor Gr
Interview Preparation Tips
Selected
I applied via Walk-in and was interviewed before Jan 2023. There were 2 interview rounds.
General Organic chemistry questions and API related questions
(1 Question)
- Q1. Salary discussion
Interview Preparation Tips
Research Scientist Interview Questions & Answers
Alembic Pharmaceuticals
Anonymous
posted on 25 Jan 2023
Selected
I applied via Naukri.com and was interviewed before Jan 2022. There was 1 interview round.
(2 Questions)
- Q1. Tell any Name Reaction you know.
- Ans.
The Grignard Reaction is a nucleophilic addition reaction between an organomagnesium halide and a carbonyl group.
Named after French chemist Victor Grignard
Used to form carbon-carbon bonds
Commonly used in organic synthesis
Example: Grignard reagent (RMgX) + aldehyde (R'CHO) -> alcohol (R'CH(OH)R)
- Q2. Detail information on projects you have done
Interview Preparation Tips
Research Scientist Interview Questions & Answers
Alembic Pharmaceuticals
Anonymous
posted on 31 Mar 2023
Selected
I applied via Approached by Company and was interviewed before Mar 2022. There were 4 interview rounds.
Fundamental of Analytical techniques, Chemistry of wet analysis, Characterisation techniques, Quantitative and qualitative analysis, Fundamentals of Chromatography, Spectroscopy, Spectrometry l, QC, QA, RA, GLP, cGMP.
(1 Question)
- Q1. Chromatography, Spectroscopy, Spectrometry, Wet analysis, API, Formulation, Characterisation techniques and Fundamentals of analytical chemistry.
(1 Question)
- Q1. Personal details and salary discussions.
Interview Preparation Tips
I applied via Naukri.com and was interviewed before Aug 2021. There were 2 interview rounds.
(6 Questions)
- Q1. 1) self introduction 2) How to develop method for Api to finished products of Assay and Related substances in injectable? 3) column chemistry? 4) method validation 5) ich guidelines
- Ans.
The interview questions cover topics such as self-introduction, developing methods for API to finished products, column chemistry, method validation, and ICH guidelines.
For self-introduction, briefly talk about your background, education, and relevant experience.
To develop a method for API to finished products, consider factors such as the desired assay and related substances, analytical techniques, and regulatory requ...
- Q2. 6)if mass balance not achieved in forced degradation then whts the possible reason??
- Ans.
Possible reasons for not achieving mass balance in forced degradation
Incomplete degradation of the analyte
Formation of unknown degradation products
Loss of analyte during sample preparation or analysis
Inaccurate measurement of sample or standard volumes
Errors in weighing or dilution of samples
Contamination of samples or equipment
Inadequate mixing or homogenization of samples
Inefficient extraction of analyte from the mat...
- Q3. 7) how to develop multimedia dissolution method?
- Ans.
Multimedia dissolution method can be developed by considering the physicochemical properties of the drug and the media used.
Select appropriate media that mimic the physiological conditions of the drug's intended site of action
Determine the solubility and stability of the drug in different media
Optimize the pH and temperature of the media to enhance drug solubility
Use appropriate equipment and techniques for sample prep...
- Q4. 8) what is sink condition in dissolution?
- Ans.
Sink condition in dissolution refers to a state where the drug being dissolved is completely solubilized and no further dissolution occurs.
Sink condition is achieved when the concentration of the drug in the dissolution medium is much lower than its solubility.
It ensures that the dissolution process is not limited by the drug's solubility but by other factors like diffusion.
Sink condition is important for accurate and ...
- Q5. 9) pka value determination and their role in development?
- Ans.
pKa value determination and their role in development
pKa value is a measure of the acidity or basicity of a compound
It helps in understanding the chemical properties and behavior of a compound
pKa values are important in drug development as they affect drug solubility, absorption, and stability
Determining pKa values can aid in optimizing drug formulations and predicting drug-drug interactions
- Q6. 10) Bsc classification and their uses.
- Ans.
Bsc classification is a system used to categorize and classify living organisms based on their characteristics.
Bsc classification stands for Biological Species Concept classification.
It is used to group organisms based on their physical and genetic characteristics.
The classification system includes Kingdom, Phylum, Class, Order, Family, Genus, and Species.
Each level of classification is based on specific characteristic...
Interview Preparation Tips
- Method Development
- Method Validation
- ich guidelines
2) you only write what is your actual job profile in your CV.
3) and finally divert interviewers towards your profile and explain it properly
Interview Questionnaire
5 Questions
- Q1. What is the role of pka in HPLC method development
- Ans.
pKa plays a crucial role in HPLC method development by determining the ionization state of analytes and their retention on the stationary phase.
pKa helps in selecting the appropriate mobile phase pH for ionizable compounds.
It influences the ionization of analytes, affecting their solubility and interaction with the stationary phase.
pKa values aid in optimizing separation by adjusting the pH to enhance selectivity and r...
- Q2. How pka value of the product is calculated
- Ans.
The pKa value of a product is calculated based on its acid dissociation constant and the concentration of the acid and its conjugate base.
pKa is a measure of the acidity or basicity of a compound.
It is calculated using the equation: pKa = -log10(Ka), where Ka is the acid dissociation constant.
The acid dissociation constant is the ratio of the concentration of the dissociated form of the acid to the concentration of the...
- Q3. Tyes of titration with mechanism
- Ans.
Titration is a technique used in chemistry to determine the concentration of a substance in a solution.
Acid-base titration: involves the reaction between an acid and a base to determine the concentration of either
Redox titration: involves the transfer of electrons between reactants to determine the concentration of a substance
Complexometric titration: involves the formation of a complex between a metal ion and a ligand...
- Q4. How to develope a HPLC Related substances method
- Ans.
Developing an HPLC related substances method involves selecting appropriate column, mobile phase, and detection wavelength.
Select a suitable column based on the analyte properties and separation requirements.
Optimize the mobile phase composition and gradient program for efficient separation.
Choose an appropriate detection wavelength based on the analyte's UV absorption properties.
Validate the method by testing specific...
- Q5. How many types of GC Capillary column and which one is best& why
- Ans.
There are several types of GC capillary columns, including non-polar, polar, and specialty columns. The best type depends on the specific application and analytes being analyzed.
Non-polar columns are best for separating non-polar compounds, such as hydrocarbons.
Polar columns are ideal for separating polar compounds, such as alcohols and acids.
Specialty columns, like chiral columns, are used for separating enantiomers.
F...
Rohit Sharma
Selected
I applied via Naukri.com and was interviewed before Aug 2023. There were 3 interview rounds.
(1 Question)
- Q1. Experience discussion
Experience related questions and some chemistry.
(1 Question)
- Q1. Experience discussion
Research Scientist Interview Questions & Answers
Intas Pharmaceuticals
Anonymous
posted on 1 Jun 2024
Selected
I applied via LinkedIn and was interviewed before Jun 2023. There were 2 interview rounds.
(1 Question)
- Q1. Details about yourself
Discussion related to previous experience
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