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Mankind Pharma
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I applied via Naukri.com and was interviewed before Aug 2023. There were 3 interview rounds.
Experience related questions and some chemistry.
I applied via Walk-in and was interviewed before Jan 2023. There were 2 interview rounds.
General Organic chemistry questions and API related questions
pKa plays a crucial role in HPLC method development by determining the ionization state of analytes and their retention on the stationary phase.
pKa helps in selecting the appropriate mobile phase pH for ionizable compounds.
It influences the ionization of analytes, affecting their solubility and interaction with the stationary phase.
pKa values aid in optimizing separation by adjusting the pH to enhance selectivity and r...
The pKa value of a product is calculated based on its acid dissociation constant and the concentration of the acid and its conjugate base.
pKa is a measure of the acidity or basicity of a compound.
It is calculated using the equation: pKa = -log10(Ka), where Ka is the acid dissociation constant.
The acid dissociation constant is the ratio of the concentration of the dissociated form of the acid to the concentration of the...
Titration is a technique used in chemistry to determine the concentration of a substance in a solution.
Acid-base titration: involves the reaction between an acid and a base to determine the concentration of either
Redox titration: involves the transfer of electrons between reactants to determine the concentration of a substance
Complexometric titration: involves the formation of a complex between a metal ion and a ligand...
Developing an HPLC related substances method involves selecting appropriate column, mobile phase, and detection wavelength.
Select a suitable column based on the analyte properties and separation requirements.
Optimize the mobile phase composition and gradient program for efficient separation.
Choose an appropriate detection wavelength based on the analyte's UV absorption properties.
Validate the method by testing specific...
There are several types of GC capillary columns, including non-polar, polar, and specialty columns. The best type depends on the specific application and analytes being analyzed.
Non-polar columns are best for separating non-polar compounds, such as hydrocarbons.
Polar columns are ideal for separating polar compounds, such as alcohols and acids.
Specialty columns, like chiral columns, are used for separating enantiomers.
F...
I applied via Naukri.com and was interviewed before Aug 2021. There were 2 interview rounds.
The interview questions cover topics such as self-introduction, developing methods for API to finished products, column chemistry, method validation, and ICH guidelines.
For self-introduction, briefly talk about your background, education, and relevant experience.
To develop a method for API to finished products, consider factors such as the desired assay and related substances, analytical techniques, and regulatory requ...
Possible reasons for not achieving mass balance in forced degradation
Incomplete degradation of the analyte
Formation of unknown degradation products
Loss of analyte during sample preparation or analysis
Inaccurate measurement of sample or standard volumes
Errors in weighing or dilution of samples
Contamination of samples or equipment
Inadequate mixing or homogenization of samples
Inefficient extraction of analyte from the mat...
Multimedia dissolution method can be developed by considering the physicochemical properties of the drug and the media used.
Select appropriate media that mimic the physiological conditions of the drug's intended site of action
Determine the solubility and stability of the drug in different media
Optimize the pH and temperature of the media to enhance drug solubility
Use appropriate equipment and techniques for sample prep...
Sink condition in dissolution refers to a state where the drug being dissolved is completely solubilized and no further dissolution occurs.
Sink condition is achieved when the concentration of the drug in the dissolution medium is much lower than its solubility.
It ensures that the dissolution process is not limited by the drug's solubility but by other factors like diffusion.
Sink condition is important for accurate and ...
pKa value determination and their role in development
pKa value is a measure of the acidity or basicity of a compound
It helps in understanding the chemical properties and behavior of a compound
pKa values are important in drug development as they affect drug solubility, absorption, and stability
Determining pKa values can aid in optimizing drug formulations and predicting drug-drug interactions
Bsc classification is a system used to categorize and classify living organisms based on their characteristics.
Bsc classification stands for Biological Species Concept classification.
It is used to group organisms based on their physical and genetic characteristics.
The classification system includes Kingdom, Phylum, Class, Order, Family, Genus, and Species.
Each level of classification is based on specific characteristic...
Mankind Pharma interview questions for designations
Top trending discussions
posted on 29 Dec 2022
I applied via Approached by Company and was interviewed before Dec 2021. There were 4 interview rounds.
posted on 1 Jun 2024
I applied via LinkedIn and was interviewed before Jun 2023. There were 2 interview rounds.
Discussion related to previous experience
posted on 20 Apr 2024
The percentage of buffer used in mobile phase and the use of SLS in disso and its allowed percentage.
The percentage of buffer used in the mobile phase depends on the specific experiment and the desired separation of compounds.
Buffer is used in the mobile phase to maintain the pH and ionic strength, which can affect the separation and stability of analytes.
The percentage of buffer can range from 5% to 50% or more, depen...
The sink condition is decided based on various factors such as the purpose of the sink, the type of research being conducted, and the desired outcome.
Consider the purpose of the sink - Is it for disposal, storage, or analysis of substances?
Evaluate the type of research being conducted - Does it involve chemical reactions, biological samples, or physical measurements?
Assess the desired outcome - Are you looking for pres...
The criteria/limit for impurity recovery depends on the specific research study and the desired purity level.
The criteria for impurity recovery may include the maximum allowable impurity concentration or percentage.
The limit for impurity recovery can be determined based on regulatory guidelines or industry standards.
The desired purity level may vary depending on the application or intended use of the research findings.
...
Mass balance is a principle used in various scientific disciplines to account for the mass of substances in a system.
Mass balance is based on the principle of conservation of mass, which states that mass cannot be created or destroyed, only transferred or transformed.
It involves tracking the inputs, outputs, and accumulation of mass within a system.
Mass balance equations are commonly used in environmental science, chem...
RF values are important in chromatography to identify and separate compounds.
RF value is the ratio of the distance traveled by a compound to the distance traveled by the solvent front in chromatography.
It helps in identifying and separating compounds based on their polarity and solubility.
RF values can be used to compare compounds and determine their purity.
For example, in thin-layer chromatography, RF values are used ...
posted on 20 Mar 2025
I appeared for an interview in Feb 2025, where I was asked the following questions.
Some of the top questions asked at the Mankind Pharma Research Scientist interview -
based on 4 interviews
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