Mankind Pharma Research Scientist Interview Questions and Answers

Q1. Experience discussion
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Experience related questions and some chemistry.

Q1. Experience discussion
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General Organic chemistry questions and API related questions

Q1. Salary discussion
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Q1. 1) self introduction 2) How to develop method for Api to finished products of Assay and Related substances in injectable? 3) column chemistry? 4) method validation 5) ich guidelines
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The interview questions cover topics such as self-introduction, developing methods for API to finished products, column chemistry, method validation, and ICH guidelines.
• For self-introduction, briefly talk about your background, education, and relevant experience.

• To develop a method for API to finished products, consider factors such as the desired assay and related substances, analytical techniques, and regulatory requ...read more
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Q2. 6)if mass balance not achieved in forced degradation then whts the possible reason??
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Possible reasons for not achieving mass balance in forced degradation
• Incomplete degradation of the analyte

• Formation of unknown degradation products

• Loss of analyte during sample preparation or analysis

• Inaccurate measurement of sample or standard volumes

• Errors in weighing or dilution of samples

• Contamination of samples or equipment

• Inadequate mixing or homogenization of samples

• Inefficient extraction of analyte from the mat...read more
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Q3. 7) how to develop multimedia dissolution method?
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Multimedia dissolution method can be developed by considering the physicochemical properties of the drug and the media used.
• Select appropriate media that mimic the physiological conditions of the drug's intended site of action

• Determine the solubility and stability of the drug in different media

• Optimize the pH and temperature of the media to enhance drug solubility

• Use appropriate equipment and techniques for sample prep...read more
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Q4. 8) what is sink condition in dissolution?
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Sink condition in dissolution refers to a state where the drug being dissolved is completely solubilized and no further dissolution occurs.
• Sink condition is achieved when the concentration of the drug in the dissolution medium is much lower than its solubility.

• It ensures that the dissolution process is not limited by the drug's solubility but by other factors like diffusion.

• Sink condition is important for accurate and ...read more
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Q5. 9) pka value determination and their role in development?
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pKa value determination and their role in development
• pKa value is a measure of the acidity or basicity of a compound

• It helps in understanding the chemical properties and behavior of a compound

• pKa values are important in drug development as they affect drug solubility, absorption, and stability

• Determining pKa values can aid in optimizing drug formulations and predicting drug-drug interactions
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Q6. 10) Bsc classification and their uses.
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Bsc classification is a system used to categorize and classify living organisms based on their characteristics.
• Bsc classification stands for Biological Species Concept classification.

• It is used to group organisms based on their physical and genetic characteristics.

• The classification system includes Kingdom, Phylum, Class, Order, Family, Genus, and Species.

• Each level of classification is based on specific characteristic...read more
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