8) what is sink condition in dissolution?

Question

Accepted Answer

Sink condition in dissolution refers to a state where the drug being dissolved is completely solubilized and no further dissolution occurs.

Sink condition is achieved when the concentration of the drug in the dissolution medium is much lower than its solubility.
It ensures that the dissolution process is not limited by the drug's solubility but by other factors like diffusion.
Sink condition is important for accurate and reproducible dissolution testing of pharmaceutical products.
For example, if a drug has a solubility of 100 mg/mL, achieving a concentration of 10 mg/mL in the dissolution medium would create a sink condition.

Accepted Answer

Ability of dissolution media to dissolve the three times of drug present in dosage form...

Accepted Answer

Sink condition is the ability of the dissolution media to dissolve at least 3 times the amount of drug that is in your dosage form. Having sink conditions helps your dissolution have more robustness as well as being more biologically relevant.

8) what is sink condition in dissolution?

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