70+ RuralShores Interview Questions and Answers

The question is asking about various topics related to the pharmaceutical industry and equipment used in it.

• Tunnel conveyor speed is important for efficient transportation of materials in the pharmaceutical industry.

• PM (Preventive Maintenance) is necessary to ensure the smooth operation and longevity of equipment.

• Filling room temperature needs to be controlled to maintain the stability and quality of pharmaceutical products.

• Different types of copies are issued in the pharmace...read more

An autoclave is a device used to sterilize equipment and supplies by subjecting them to high-pressure steam.

• Autoclaves use high-pressure steam to kill microorganisms and spores

• They are commonly used in medical and laboratory settings

• Autoclaves can sterilize various items such as surgical instruments, glassware, and media

• The principle behind autoclaves is the combination of high temperature and pressure to achieve effective sterilization

• Autoclaves typically operate at temperat...read more

The pharmaceutical industry involves the research, development, production, and marketing of drugs and medications.

• Pharmaceutical companies invest heavily in research and development to create new drugs.

• Regulations from government agencies like the FDA ensure safety and efficacy of pharmaceutical products.

• Pharmaceutical sales involve marketing to healthcare professionals and direct-to-consumer advertising.

• The industry is highly competitive with companies constantly seeking to...read more

I have experience handling various equipments such as computers, printers, scanners, and office machinery.

• Computers

• Printers

• Scanners

• Office machinery

Filters are used in the manufacturing industry to remove impurities, improve product quality, and protect equipment.

• Filters help remove impurities from raw materials or fluids used in the manufacturing process.

• They improve product quality by ensuring only clean materials are used.

• Filters protect equipment from damage by preventing contaminants from entering machinery.

• Examples include air filters in HVAC systems, water filters in food production, and oil filters in automotive ...read more

To overcome economic loss during Covid lockdown, one can explore alternative sources of income and seek financial assistance.

• Explore alternative sources of income such as online freelancing, selling products online, or starting a small business from home

• Seek financial assistance from government programs, non-profit organizations, or banks offering loans with low interest rates

• Reduce expenses by cutting unnecessary costs and prioritizing essential needs

• Consider upskilling or r...read more

A single-use bioreactor is a disposable bioreactor system used for the cultivation of cells or microorganisms in biotechnological processes.

• Single-use bioreactors are designed for single-use applications, eliminating the need for cleaning and sterilization between batches.

• They are commonly used in the biopharmaceutical industry for the production of vaccines, monoclonal antibodies, and other biologics.

• Single-use bioreactors offer advantages such as reduced risk of cross-conta...read more

Membrane filtration method is commonly used for the analysis of Total Aerobic Microbial Count (TAMC) in water.

• Membrane filtration method is commonly used for TAMC analysis in water

• Other methods include pour plate method and spread plate method

• Membrane filters are used to trap and grow bacteria colonies for counting

• Results are expressed as colony forming units per milliliter (CFU/mL)

Diversify revenue streams, reduce expenses, and adapt to new market demands.

• Explore new business opportunities and revenue streams

• Reduce expenses by cutting unnecessary costs

• Adapt to new market demands by pivoting business model

• Invest in digital marketing and e-commerce

• Collaborate with other businesses to create new products or services

• Offer discounts or promotions to attract customers

• Apply for government grants or loans

• Consider remote work options to reduce office expenses

The sterilization time in an autoclave varies depending on the type of material being sterilized.

• Sterilization time in an autoclave is determined by factors such as the type of material, the size and shape of the load, and the desired level of sterilization.

• For example, sterilizing surgical instruments may require a longer time compared to sterilizing laboratory glassware.

• The standard sterilization time for most materials in an autoclave is around 15-30 minutes at a temperatu...read more

The incubation temperature for bio burden varies depending on the type of microorganism.

• The temperature range for incubation can be between 20°C to 55°C.

• The optimal temperature for most bacteria is around 37°C.

• Some microorganisms require specific temperatures for incubation, such as thermophiles that grow best at temperatures above 45°C.

• The incubation time can also vary depending on the type of microorganism and the purpose of the test.

Sterility can be noticed by observing cleanliness, lack of contaminants, and proper storage of items.

• Check for cleanliness of the environment and items being used

• Look for any signs of contaminants or foreign particles

• Ensure proper storage of items to prevent contamination

• Observe if proper sterilization techniques are being followed

• Check for expiration dates on sterilization products

• Consider using indicators like color-changing tapes to verify sterilization

The function of an air conditioner is to cool and dehumidify the air in a space.

• Cools the air by removing heat and moisture

• Reduces humidity levels

• Improves air quality by filtering out dust and allergens

• Maintains a comfortable temperature

• Enhances sleep quality

• Prevents electronic devices from overheating

I operated a vial filling machine for pharmaceutical products.

• Operated a vial filling machine in a pharmaceutical manufacturing facility

• Ensured accurate filling of vials with the correct medication

• Followed standard operating procedures and safety protocols

• Performed routine maintenance and troubleshooting on the machine

• Maintained cleanliness and sterility of the machine and work area

Yes, I have experience handling 21 CFR equipments in the medical field.

• Yes, I have experience with 21 CFR Part 11 compliant software systems.

• I am familiar with the regulations outlined in 21 CFR Part 820 for medical devices.

• I have worked with equipment that complies with 21 CFR Part 210 and 211 for pharmaceuticals.

• I understand the importance of maintaining documentation and records in accordance with 21 CFR requirements.

Filter integrities are performed to ensure the quality and efficiency of the production process.

• Filter integrities involve checking the condition and performance of filters used in the production process.

• This is done to ensure that the filters are functioning properly and not clogged or damaged.

• Filter integrities are important to maintain the quality of the product and prevent contamination.

• Examples of filter integrities include bubble point testing, pressure decay testing, a...read more

I will implement techniques such as heat treatment, UV irradiation, chemical disinfection, and filtration for virus inactivation.

• Heat treatment: Applying heat to destroy viruses, commonly used in pasteurization.

• UV irradiation: Exposing viruses to ultraviolet light to inactivate them.

• Chemical disinfection: Using chemicals like bleach or alcohol to kill viruses on surfaces.

• Filtration: Passing fluids through filters to remove viruses.

Pharma revenue is expected to contribute significantly to the Indian economy.

• The Indian pharmaceutical industry is expected to reach $100 billion by 2025.

• The industry contributes to the country's GDP and provides employment opportunities.

• India is the largest provider of generic drugs globally.

• The government's initiatives to promote the industry, such as the 'Pharma Vision 2020' plan, will further boost revenue.

• Pharma revenue is expected to grow due to increasing demand for he...read more

Fire extinguishers should be kept in easily accessible locations throughout a building.

• Fire extinguishers should be placed on every floor of a building.

• They should be easily visible and accessible, preferably mounted on walls or placed on stands.

• Fire extinguishers should be located near potential fire hazards, such as kitchens or electrical equipment.

• They should be placed in well-lit areas and not obstructed by furniture or other objects.

• Regular inspections and maintenance sh...read more

Equipment and area qualifications/validations ensure that all equipment and areas meet the required standards for production.

• Equipment and areas must be qualified and validated before use in production.

• Qualification ensures that equipment is installed and operates correctly.

• Validation ensures that equipment and areas consistently produce the desired results.

• Qualification and validation processes involve testing, documentation, and approval.

• Examples of equipment and areas that...read more

Skada is a damage meter add-on for World of Warcraft, while 21 CFR refers to regulations for food and drug products in the US.

• Skada is a popular damage meter add-on used by players in World of Warcraft to track their damage output in raids and dungeons.

• 21 CFR stands for Title 21 of the Code of Federal Regulations, which contains regulations for food and drug products in the United States.

• 21 CFR covers various aspects such as good manufacturing practices, labeling requirements...read more

Autoclave sterilization is a process that uses steam and high pressure to kill microorganisms and sterilize equipment.

• Autoclave sterilization is commonly used in medical and laboratory settings.

• The process involves placing items in a sealed chamber and subjecting them to steam at a high temperature and pressure.

• The steam penetrates the items, killing bacteria, viruses, and other microorganisms.

• Autoclave sterilization is effective in sterilizing surgical instruments, laborator...read more

The principle of a pH electrode is based on the measurement of the potential difference between a reference electrode and a glass electrode.

• pH electrodes consist of a glass membrane that responds to changes in hydrogen ion concentration in a solution

• The glass membrane generates a potential difference proportional to the pH of the solution

• The reference electrode provides a stable potential for comparison

• The pH meter measures the potential difference and converts it to pH value...read more

BET validation aims to ensure the accuracy and reliability of analytical results obtained from BET surface area measurements.

• BET validation is necessary to ensure the quality of analytical results.

• It involves verifying the accuracy and precision of the instrument used for BET surface area measurements.

• BET validation also includes checking the validity of the assumptions made during the analysis.

• Examples of BET validation methods include using standard reference materials and ...read more

The media percentage of mediafill refers to the proportion of media used in a mediafill test.

• Mediafill is a process used in the pharmaceutical industry to simulate aseptic manufacturing conditions.

• It involves filling sterile media into containers to test the effectiveness of the aseptic process.

• The media percentage refers to the amount of media used in relation to the total volume of the container.

• The specific media percentage may vary depending on the requirements of the tes...read more

Change control is a process that ensures all changes to a system are documented, reviewed, approved, and implemented in a controlled manner.

• Change control is essential for maintaining the stability and integrity of a system.

• It involves documenting and tracking all proposed changes, including their impact and risks.

• Changes are reviewed and approved by a designated change control board or committee.

• Proper testing and validation are conducted before implementing changes to minim...read more

Autoclave temperature refers to the temperature at which an autoclave operates to sterilize equipment and materials.

• Autoclave temperature is typically set between 121-134 degrees Celsius.

• Higher temperatures are used for faster sterilization, while lower temperatures are used for delicate materials.

• Autoclave temperature is crucial to ensure effective sterilization and prevent the spread of infections.

• Monitoring and controlling autoclave temperature is essential to maintain the...read more

Technical features and design and development are crucial for successful product development.

• Technical features should be aligned with the product's purpose and target audience.

• Design and development should be user-centered and iterative.

• Collaboration between technical and design teams is essential for seamless integration.

• Regular testing and feedback loops ensure continuous improvement.

• Examples: Apple's iPhone design and development process, Tesla's electric vehicle technolo...read more

The acceptance limit for GPT varies depending on the laboratory and the method used.

• GPT is an enzyme found in the liver and is used as a marker for liver damage.

• The acceptance limit for GPT is determined by the laboratory performing the test and can vary depending on the method used.

• In general, a normal range for GPT is between 10 and 40 units per liter of blood.

• However, this range may differ depending on the age, sex, and overall health of the patient.

• Abnormal levels of GPT ...read more

The type of level sensor commonly used in fermenters is a capacitance level sensor.

• Capacitance level sensor is commonly used in fermenters to measure the level of liquid or solid materials.

• This type of sensor works by detecting changes in capacitance as the level of the material changes.

• Capacitance level sensors are accurate, reliable, and suitable for various types of fermenters.

• Other types of level sensors used in fermenters include ultrasonic sensors and pressure sensors.

Qualifying a manual inspection booth involves assessing its functionality, safety measures, and adherence to regulations.

• Evaluate the booth's functionality by checking if it meets the required specifications and standards.

• Assess the safety measures in place, such as proper ventilation, lighting, and emergency exits.

• Ensure that the booth complies with relevant regulations and guidelines, such as those related to hygiene and worker safety.

• Inspect the equipment and tools used in...read more

Media fill simulations are tests conducted to ensure the sterility of aseptic manufacturing processes.

• Media fill simulations involve filling sterile media into containers under aseptic conditions.

• The containers are then incubated to check for any microbial growth.

• The purpose of media fill simulations is to validate the aseptic manufacturing process and ensure that it is capable of producing sterile products.

• These simulations are required by regulatory agencies such as the FDA...read more

Incident is an unexpected event that may or may not have an impact on product quality, while deviation is a planned or intentional change that may affect product quality.

• Incident is unplanned, while deviation is planned

• Incident may or may not have an impact on product quality, while deviation may affect product quality

• Incident requires investigation to determine the root cause, while deviation requires investigation to determine the impact on product quality

• Examples of incide...read more

I am currently working as a Quality Control Analyst in a pharmaceutical company.

• Types of components in HPLC include stationary phase, mobile phase, column, injector, detector, and data system.

• Detectors commonly used in HPLC are UV-Vis detector, fluorescence detector, refractive index detector, and mass spectrometry detector.

Aseptic media fill validation is a critical process to ensure the sterility of pharmaceutical products.

• Aseptic media fill validation is a process of simulating the manufacturing process to ensure that the aseptic technique is maintained throughout the process.

• It is important to comply with FDA guidelines to ensure the safety and efficacy of pharmaceutical products.

• The FDA requires aseptic media fill validation to be performed annually and after any significant changes to the ...read more

The limit of water BET refers to the maximum amount of water that can be adsorbed onto a material's surface using the BET method.

• The limit of water BET is typically around 40-50% relative humidity.

• It is important to consider the specific surface area and pore size distribution of the material when determining the water BET limit.

• For example, materials with larger surface areas and smaller pore sizes may have higher water BET limits.

• The water BET limit can also vary depending ...read more

Manual visual inspection process involves visually examining a product or material to ensure it meets quality standards.

• The process involves trained personnel inspecting the product or material for defects or abnormalities.

• The inspection may be done using specialized equipment such as magnifying glasses or microscopes.

• The process may be time-consuming and require a lot of attention to detail.

• Examples include inspecting electronic components for defects, inspecting food produc...read more

Tunnel temperatures vary depending on the location and time of day.

• Tunnel temperatures can be affected by factors such as ventilation, insulation, and proximity to heat sources.

• In general, tunnels tend to be cooler than the surrounding environment due to lack of sunlight and air flow.

• However, temperatures can rise significantly in areas with heavy traffic or machinery.

• Regular monitoring and maintenance of tunnel temperature control systems is important for safety and comfort ...read more

Risk management is the process of identifying, assessing, and prioritizing potential risks and taking measures to minimize or mitigate their impact.

• Identifying potential risks

• Assessing the likelihood and impact of each risk

• Prioritizing risks based on their severity

• Developing strategies to minimize or mitigate risks

• Implementing risk management plans

• Monitoring and reviewing risks regularly

• Examples: financial risk, cybersecurity risk, project risk

Trouble shooting during cycle development

• Identify the problem or issue

• Analyze the root cause

• Develop a plan to resolve the problem

• Implement the plan

• Monitor and evaluate the results

• Make necessary adjustments if needed

The fast moving medicine name is Crocin.

• Crocin is a popular pain reliever and fever reducer.

• It contains paracetamol as its active ingredient.

• It is available in various forms like tablets, syrup, and drops.

Vial washing cycle is a process of cleaning and sterilizing vials used in pharmaceutical or medical industries.

• Vial washing cycle involves multiple steps such as pre-rinsing, washing, rinsing, and drying.

• The purpose of the cycle is to remove any contaminants or residues from the vials to ensure their cleanliness and sterility.

• Different types of washing solutions or detergents may be used depending on the requirements.

• The cycle may include mechanical or manual washing methods....read more

VMP stands for Vendor Master Plan. It is a strategic document that outlines the approach and activities for managing vendors in an organization.

• VMP is a comprehensive plan that includes vendor selection, evaluation, and performance management.

• It defines the criteria for selecting vendors and the process for evaluating their performance.

• The plan also outlines the responsibilities and roles of various stakeholders involved in vendor management.

• VMP helps in ensuring that vendors...read more

Expectations for the Senior Officer role

• Demonstrate strong leadership skills

• Ability to make strategic decisions

• Excellent communication and interpersonal skills

• Proven track record of achieving targets

• Ability to work under pressure and meet deadlines

I have experience managing manpower and security systems effectively to ensure a safe and secure environment.

• Implemented efficient scheduling and deployment of security personnel to cover all shifts and areas.

• Utilized security technology such as CCTV cameras and access control systems to enhance overall security measures.

• Conducted regular training sessions for security staff to ensure they are well-equipped to handle any security threats.

• Developed and implemented emergency re...read more

The packing department is responsible for packaging and preparing products for shipment.

• Inspecting products for quality and accuracy

• Selecting appropriate packaging materials

• Assembling and labeling packages

• Operating packaging machinery

• Maintaining a clean and organized work area

There are several types of reactors used in various industries, including nuclear reactors, chemical reactors, and biological reactors.

• Nuclear reactors are used to generate electricity through nuclear fission, such as pressurized water reactors and boiling water reactors.

• Chemical reactors are used in the production of chemicals and pharmaceuticals, such as batch reactors, continuous stirred-tank reactors, and fixed-bed reactors.

• Biological reactors are used in biotechnology an...read more

Processes handling capabilities refer to the ability of a manager to effectively manage and oversee various processes within an organization.

• Ability to streamline workflows and optimize efficiency

• Strong organizational skills to prioritize tasks and allocate resources effectively

• Experience in implementing and improving processes to achieve desired outcomes

• Effective communication skills to coordinate with team members and stakeholders

• Knowledge of industry best practices and too...read more

Visual inspection involves examining an object or area using the naked eye or with the aid of tools.

• Visual inspection is a non-destructive testing method used to detect surface defects, cracks, corrosion, and other imperfections.

• It can be performed manually or with the help of specialized equipment such as borescopes, endoscopes, and magnifying glasses.

• Visual inspection is commonly used in industries such as manufacturing, aerospace, automotive, and construction.

• Examples of v...read more

Developed a project to automate library management system in college.

• Researched existing library management systems for inspiration

• Designed user-friendly interface for librarians and students

• Implemented features like book search, check-in/check-out, and overdue notifications

• Tested the system with real data to ensure functionality

• Received positive feedback from users and faculty members

Chromatography is a technique used to separate and analyze mixtures of chemicals.

• Types of chromatography include gas chromatography, liquid chromatography, ion exchange chromatography, and affinity chromatography.

• Gas chromatography separates volatile compounds based on their boiling points.

• Liquid chromatography separates non-volatile compounds based on their interactions with a stationary phase.

• Ion exchange chromatography separates charged molecules based on their charge.

• Affi...read more

To convince a doctor, one must have a thorough knowledge of the product, understand the doctor's needs, and build a strong relationship.

• Research the doctor's background and practice to understand their needs and preferences

• Present the product's benefits and how it can address the doctor's needs

• Provide clinical data and studies to support the product's efficacy

• Build a strong relationship with the doctor by being reliable, responsive, and providing excellent customer service

• Fol...read more

The first law of thermodynamics states that energy cannot be created or destroyed, only transferred or converted from one form to another.

• Energy is a conserved quantity in thermodynamics.

• It can be transferred as heat or work.

• The change in internal energy of a system is equal to the heat added to the system minus the work done by the system.

• For example, when a gas expands and does work on its surroundings, its internal energy decreases.

• Similarly, when heat is added to a system...read more

I handle situations by analyzing the problem, identifying possible solutions, and implementing the best course of action.

• Listen actively to understand the situation

• Analyze the problem and identify possible solutions

• Evaluate the pros and cons of each solution

• Implement the best course of action

• Monitor the situation and adjust as necessary

To convert RPM to g force, use the formula: g force = (RPM^2 * radius) / 705.6

• Calculate the radius of the rotating object

• Square the RPM value

• Multiply the squared RPM value by the radius

• Divide the result by 705.6 to get the g force

Buffer preparation involves mixing a weak acid and its conjugate base to maintain a stable pH.

• Dissolve the weak acid in water

• Add the conjugate base to the solution

• Adjust the pH as needed with a strong acid or base

• Use a pH meter to ensure the desired pH is achieved

• Common buffers include phosphate buffer, acetate buffer, and Tris buffer

Contained chlorophil refers to the chlorophyll that is present within the chloroplasts of plant cells.

• Chlorophyll is a green pigment that is responsible for photosynthesis in plants.

• Chloroplasts are organelles found in plant cells that contain chlorophyll.

• Contained chlorophyll is not visible to the naked eye and can only be seen under a microscope.

• The presence of contained chlorophyll can indicate the health and vitality of a plant.

• Contained chlorophyll can also be used in va...read more

P2P cycle refers to the process of procuring goods or services from a supplier and making payments for them.

• The cycle starts with identifying the need for goods or services.

• The next step is to create a purchase order (PO) and send it to the supplier.

• The supplier then delivers the goods or services and sends an invoice to the buyer.

• The buyer verifies the invoice and matches it with the PO and goods received.

• If everything matches, the buyer approves the invoice and makes paymen...read more

I am currently earning X and expecting Y based on my experience and skills.

• Mention your current salary and the salary you are expecting

• Explain why you are expecting the mentioned salary

• Consider the industry standards and your experience while deciding the expected CTC

• Be open to negotiation if required

RO water parameters refer to the quality and characteristics of water produced by reverse osmosis process.

• RO water should have a pH level between 6.5 and 8.5

• Total dissolved solids (TDS) should be less than 500 ppm

• RO water should be free from bacteria, viruses, and other harmful contaminants

• The water should have a low level of hardness and alkalinity

• RO water should be stored in a clean and sanitized container

PCR stands for Polymerase Chain Reaction, a technique used in molecular biology to amplify a single or a few copies of a piece of DNA.

• PCR is a common technique used in molecular biology to make multiple copies of a specific DNA segment.

• It involves a series of temperature changes to denature, anneal, and extend DNA strands.

• PCR is used in various applications such as DNA sequencing, gene cloning, and genetic testing.

• Examples of PCR-based tests include COVID-19 testing and pater...read more

Lyophilization is a technique used to remove water from a product by freeze-drying it.

• Lyophilization involves freezing the product and then subjecting it to a vacuum to remove the frozen water through sublimation.

• This technique is commonly used in the pharmaceutical industry to preserve drugs and vaccines.

• Lyophilization helps to extend the shelf life of products and maintain their stability.

• It is also used in the food industry to preserve perishable items like fruits, vegetab...read more

I have 5 years of experience working as a Security Officer in various settings.

• Worked in retail, corporate, and residential security roles

• Trained in emergency response procedures

• Experience with access control systems and CCTV monitoring

• Strong communication and conflict resolution skills

• Knowledge of security protocols and regulations

Modified masters require approval before use.

• Modified masters should be reviewed by a qualified individual before being approved for use.

• Approval should be documented and stored for future reference.

• Any changes made to the master should also be documented and approved.

• Examples of modified masters include updated test methods or revised specifications.

cGMP stands for current Good Manufacturing Practices and refers to the regulations and guidelines set by the FDA for ensuring quality and safety in pharmaceutical manufacturing.

• cGMP is a set of guidelines and regulations that ensure the quality, safety, and efficacy of pharmaceutical products.

• It covers all aspects of the manufacturing process, from raw materials to finished products.

• cGMP requires manufacturers to maintain detailed records and to follow strict procedures for t...read more

Packing and labelling guidelines ensure products are properly packaged and labeled for distribution and sale.

• Follow specific packaging requirements for different products (e.g. fragile items, perishable goods)

• Use appropriate labeling with product information, barcodes, and expiration dates

• Ensure packaging is secure and protects the product during transportation

• Comply with regulations and standards for packaging and labeling in the industry

• Train staff on proper packing and lab...read more

ICH guidelines are a set of international guidelines for the development, registration, and post-approval of pharmaceuticals.

• ICH stands for International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use

• Guidelines cover topics such as clinical trials, quality control, and safety reporting

• Examples include ICH E6 for Good Clinical Practice and ICH Q9 for Quality Risk Management

Lyo is a process of freeze-drying a substance to remove moisture and preserve it.

• The substance is frozen at a low temperature

• A vacuum is applied to remove the moisture

• The temperature is slowly raised to allow sublimation of the ice

• The dried substance is sealed in a container to prevent moisture absorption

• Used for preserving food, pharmaceuticals, and biological samples