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Biocon Limited

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90+ Interview Questions and Answers

Updated 30 Nov 2024
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Q1. Why if adding acid pH value get decreasing and adding alkali pH value is increasing

Ans.

The pH value decreases when acid is added and increases when alkali is added.

  • Acids release hydrogen ions (H+) when dissolved in water, which increases the concentration of H+ ions and lowers the pH value.

  • Alkalis release hydroxide ions (OH-) when dissolved in water, which decreases the concentration of H+ ions and raises the pH value.

  • The pH scale ranges from 0 to 14, with 7 being neutral. Values below 7 are acidic, and values above 7 are alkaline.

  • For example, adding lemon juic...read more

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Q2. How to handle Reactors,what is documentation,Deviation,validation,data integrity,etc.

Ans.

Handling Reactors involves proper documentation, deviation management, validation, and ensuring data integrity.

  • Maintain accurate and detailed documentation of all reactor operations and processes.

  • Implement a deviation management system to identify and address any deviations from standard procedures.

  • Validate all reactor processes to ensure they meet regulatory requirements and industry standards.

  • Ensure data integrity by implementing appropriate controls and procedures to preve...read more

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Q3. What is HPLC/principle/instrumentation/normal and reverse phase/detectors

Ans.

HPLC is a technique used to separate, identify, and quantify components in a mixture based on their interaction with a stationary phase and mobile phase.

  • HPLC stands for High-Performance Liquid Chromatography.

  • The principle of HPLC involves the separation of components in a mixture based on their affinity for the stationary phase and mobile phase.

  • The instrumentation of HPLC includes a pump to deliver the mobile phase, a sample injector, a column containing the stationary phase,...read more

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Q4. Working principle of equipments which are used in pharmaceutical industry

Ans.

Equipments used in pharmaceutical industry operate on various principles depending on their function.

  • Mixing and blending equipment use principles of agitation and shear to mix ingredients

  • Milling equipment use principles of compression, impact, and attrition to reduce particle size

  • Filtration equipment use principles of size exclusion and adsorption to separate solids from liquids

  • Sterilization equipment use principles of heat, radiation, or chemicals to kill microorganisms

  • Packa...read more

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Q5. What is uv spectroscopy/principle/use/beer Lambert law/instrumentation. Etc

Ans.

UV spectroscopy is a technique that uses ultraviolet light to analyze the chemical composition of substances.

  • UV spectroscopy is based on the principle that molecules absorb ultraviolet light at specific wavelengths.

  • The Beer-Lambert law relates the concentration of a substance to the amount of light it absorbs.

  • UV spectroscopy is commonly used in pharmaceutical, environmental, and forensic analysis.

  • It is used to determine the concentration of a substance, identify unknown compo...read more

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Q6. 5.Calibration of instruments which I mentioned in my resume

Ans.

Calibration of instruments is a crucial process to ensure accuracy and reliability of measurements.

  • Calibration involves comparing the measurements of an instrument to a known standard.

  • It helps in identifying and correcting any deviations or errors in the instrument's readings.

  • Calibration ensures that the instrument is performing within acceptable limits and provides accurate results.

  • It is necessary to calibrate instruments regularly to maintain their performance and reliabili...read more

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Q7. Which types of machines are used in pharmaceutical company

Ans.

Pharmaceutical companies use various types of machines for different purposes.

  • Mixing and blending machines for preparing medicines

  • Tablet compression machines for making tablets

  • Capsule filling machines for filling capsules

  • Liquid filling machines for filling liquid medicines

  • Labeling machines for labeling medicines

  • Packaging machines for packaging medicines

  • Sterilization machines for sterilizing equipment and medicines

  • Drying machines for drying medicines

  • Milling machines for grindi...read more

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Q8. Definition and working and different types of pumps and boilers ??

Ans.

Pumps and boilers are essential equipment in various industries. Pumps are used to transfer fluids, while boilers generate steam.

  • Pumps are devices that move fluids by mechanical action.

  • There are different types of pumps, such as centrifugal pumps, reciprocating pumps, and rotary pumps.

  • Centrifugal pumps are commonly used in water supply systems and HVAC applications.

  • Reciprocating pumps are used in high-pressure applications, like oil and gas industry.

  • Rotary pumps are used for ...read more

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Q9. Explain about SAP activity

Ans.

SAP activity refers to the use of SAP software for business operations and management.

  • SAP activity involves using SAP software for various business functions such as finance, human resources, supply chain management, and customer relationship management.

  • It helps organizations streamline their processes, improve efficiency, and make data-driven decisions.

  • Examples of SAP activity include creating financial reports, managing employee data, tracking inventory, and analyzing custo...read more

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Q10. Share the all document and fill the all application.

Ans.

Provide all necessary documents and complete the application form.

  • Ensure all required documents such as identification, resume, and references are included.

  • Fill out the application form accurately and completely.

  • Double check for any errors or missing information before submitting.

  • Submit the documents and application by the deadline.

  • Follow up with the organization if needed.

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Q11. What is GC/principle/instrumentation/use/detectors

Ans.

GC stands for Gas Chromatography, a principle and instrumentation used for separating and analyzing volatile compounds.

  • GC is a technique used in analytical chemistry to separate and identify components of a mixture.

  • It involves injecting a sample into a gas chromatograph, which vaporizes the sample and carries it through a column.

  • The column contains a stationary phase that interacts with the sample components, causing them to separate based on their chemical properties.

  • Detecto...read more

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Q12. How many elements are there in periodic table?

Ans.

There are 118 elements in the periodic table.

  • There are 118 known elements in the periodic table.

  • Elements are organized by atomic number, electron configuration, and recurring chemical properties.

  • Examples of elements include hydrogen, oxygen, gold, and uranium.

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Q13. Exposure in LSS projects handling and problem-solving as an individual? What challenges are faced by you and how did you overcome these challenges?

Ans.

I have extensive experience in leading Lean Six Sigma projects and solving operational problems.

  • Led multiple LSS projects focusing on process improvement and cost reduction

  • Utilized DMAIC methodology to identify root causes and implement solutions

  • Faced challenges such as resistance to change from team members or lack of data for analysis

  • Overcame challenges by effectively communicating the benefits of the project, providing training, and collaborating with cross-functional team...read more

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Q14. Explain HPLC principle anf instrumentation and working process

Ans.

HPLC is a chromatography technique used to separate compounds in a mixture based on their interactions with a stationary phase and a mobile phase.

  • HPLC principle involves passing a sample mixture through a column containing a stationary phase, where different compounds interact differently and are separated based on their affinity for the stationary phase.

  • HPLC instrumentation includes a pump to deliver the mobile phase, a sample injector, a column where separation occurs, a de...read more

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Q15. Why SF6 gas is used in circuit breakers?

Ans.

SF6 gas is used in circuit breakers due to its excellent electrical insulation properties and high dielectric strength.

  • SF6 gas has high dielectric strength, making it an effective insulator in high voltage applications.

  • It has excellent arc-quenching properties, allowing it to quickly extinguish electrical arcs.

  • SF6 gas is chemically stable and non-toxic, making it safe for use in circuit breakers.

  • It has a high thermal conductivity, which helps in dissipating heat generated dur...read more

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Q16. Hplc principle technique used in Separation of mixture of use in compound use in the mixture

Ans.

HPLC (High Performance Liquid Chromatography) is a technique used for separating mixtures of compounds based on their interactions with a stationary phase and a mobile phase.

  • HPLC separates compounds based on their affinity for the stationary phase in a column

  • It is commonly used in pharmaceutical, environmental, and food industries for analyzing and purifying compounds

  • Examples of compounds separated using HPLC include drugs, pesticides, amino acids, and vitamins

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Q17. Explain about pH activity

Ans.

pH activity refers to the measurement of acidity or alkalinity of a solution.

  • pH activity is measured on a scale of 0-14, with 7 being neutral, below 7 being acidic, and above 7 being alkaline

  • It is important in various fields such as chemistry, biology, and environmental science

  • For example, pH activity is used to determine the acidity of soil for agriculture, the pH of water for aquatic life, and the pH of blood for medical diagnosis

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Q18. 2.what are method validation parameters and what is the acceptance limits

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Q19. 3.types of Validations and way of handling

Ans.

There are three types of validations: front-end, back-end, and database. Each type requires a different approach.

  • Front-end validation is done on the client-side and checks for user input errors before submitting the form.

  • Back-end validation is done on the server-side and checks for errors in the data submitted by the user.

  • Database validation checks for data integrity and consistency in the database.

  • Handling of validation errors can be done by displaying error messages to the ...read more

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Q20. How to handel sodium cyanide

Ans.

Sodium cyanide should be handled with extreme caution due to its highly toxic nature.

  • Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and respirators.

  • Store sodium cyanide in a secure, well-ventilated area away from incompatible materials.

  • Use proper handling techniques such as avoiding skin contact and not inhaling dust or fumes.

  • Dispose of sodium cyanide properly according to local regulations.

  • In case of exposure, seek medical attention immediately...read more

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Q21. End to end explanation of inventory Management reports in SAP BW.

Ans.

Inventory Management reports in SAP BW provide end-to-end visibility of inventory levels and movements.

  • Inventory Management reports in SAP BW help track inventory levels and movements across the supply chain.

  • These reports provide real-time data on stock levels, goods receipts, and goods issues.

  • They also help identify slow-moving or obsolete inventory, and optimize inventory levels to reduce costs.

  • Examples of inventory management reports in SAP BW include stock overview, mater...read more

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Q22. AMV guidelines and method validation parameters

Ans.

AMV guidelines and method validation parameters are essential for ensuring the accuracy and reliability of analytical methods.

  • AMV guidelines provide a framework for validating analytical methods to ensure they meet the required standards.

  • Method validation parameters include specificity, accuracy, precision, linearity, range, and robustness.

  • Examples of method validation parameters include determining the limit of detection and quantification, evaluating the recovery of analyte...read more

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Q23. Write a chemical reaction

Ans.

Chemical reaction between sodium and chlorine

  • Sodium (Na) reacts with chlorine (Cl) to form sodium chloride (NaCl)

  • The reaction is exothermic and releases energy in the form of heat and light

  • The balanced chemical equation is 2Na + Cl2 -> 2NaCl

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Q24. What is Molarity, molality,normality,UV range

Ans.

Molarity, molality, and normality are measures of concentration in chemistry. UV range refers to the range of ultraviolet light.

  • Molarity is the number of moles of solute per liter of solution.

  • Molality is the number of moles of solute per kilogram of solvent.

  • Normality is the number of equivalents of solute per liter of solution.

  • UV range refers to the range of wavelengths of ultraviolet light, typically between 10 and 400 nanometers.

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Q25. Will you be comfortable working in API environment and do you have any prior experience on API industry?

Ans.

Yes, I am comfortable working in an API environment and have prior experience in the API industry.

  • I have experience working with various APIs such as REST, SOAP, and GraphQL.

  • I am familiar with API documentation, testing, and troubleshooting.

  • I have successfully implemented API integrations in previous roles.

  • I understand the importance of security and scalability in API development.

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Q26. What is noble gases in periodic table?

Ans.

Noble gases are a group of chemical elements with very low reactivity and full outer electron shells.

  • Noble gases are located in Group 18 of the periodic table.

  • They are also known as inert gases because they rarely react with other elements.

  • Examples of noble gases include helium, neon, argon, krypton, xenon, and radon.

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Q27. All Documents you Having or not?

Ans.

Yes, I have all the documents required for the interview.

  • I have all necessary documents in a folder

  • I have copies of my resume, cover letter, and references

  • I have any certifications or licenses related to the position

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Q28. what is technical skills?

Ans.

Technical skills refer to the specific knowledge and abilities required to perform tasks related to a particular field or profession.

  • Technical skills are practical and hands-on abilities that are acquired through training, education, and experience.

  • They involve the use of tools, equipment, software, and techniques specific to a particular field.

  • Examples of technical skills for a QA QC Chemist may include proficiency in analytical instruments, knowledge of quality control proc...read more

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Q29. TFF and CFF differences

Ans.

TFF is a measure of cash generated from operations, while CFF is a measure of cash generated from financing activities.

  • TFF stands for 'Total Funds From Operations' and measures the cash generated from a company's core business operations.

  • CFF stands for 'Cash Flow From Financing' and measures the cash generated from financing activities such as issuing stocks or bonds.

  • TFF is an important metric for evaluating a company's ability to generate cash from its operations, while CFF ...read more

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Q30. What is the working of ahu ?

Ans.

AHU stands for Air Handling Unit. It is a device used to regulate and circulate air as part of a heating, ventilation, and air conditioning (HVAC) system.

  • AHU is responsible for conditioning and distributing air within a building.

  • It consists of components like fans, filters, heating and cooling coils, dampers, and controls.

  • The fans in AHU draw in outside air, filter it, and then distribute it to various areas of the building.

  • The filters in AHU remove dust, pollen, and other pa...read more

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Q31. What protections are used in a substation?

Ans.

Substations use various protections to ensure safety and reliability of power supply.

  • Overcurrent protection

  • Ground fault protection

  • Transformer protection

  • Surge protection

  • Circuit breaker

  • Relay protection

  • Isolation switches

  • Lightning arresters

  • Fire protection

  • Security measures

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Q32. what is HPLC principle

Ans.

HPLC principle is based on the separation of compounds using a liquid mobile phase and a solid stationary phase.

  • HPLC stands for High Performance Liquid Chromatography.

  • It is a widely used analytical technique in chemistry and biochemistry.

  • The principle involves the separation of compounds based on their interaction with the stationary phase.

  • The mobile phase, usually a liquid solvent, carries the sample through the stationary phase.

  • Different compounds interact differently with ...read more

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Q33. What is the pH formula?

Ans.

The pH formula is used to calculate the acidity or alkalinity of a solution.

  • pH = -log[H+]

  • pH = -log[H3O+]

  • pH = log(1/[H+])

  • pH = log(1/[H3O+])

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Q34. Determination of Lod and Loq values

Ans.

LOD and LOQ values are determined based on signal-to-noise ratio and standard deviation of the response.

  • LOD (Limit of Detection) is the lowest concentration of an analyte that can be reliably detected but not necessarily quantified.

  • LOQ (Limit of Quantification) is the lowest concentration of an analyte that can be reliably measured and quantified.

  • LOD is typically determined as 3 times the standard deviation of the blank signal.

  • LOQ is usually set at 10 times the standard devia...read more

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Q35. What factors effect recovery in method development.

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Q36. what is technical knowledge

Ans.

Technical knowledge refers to the understanding and expertise in a specific field or subject, including its principles, theories, and practical applications.

  • Technical knowledge involves having a deep understanding of the subject matter and being able to apply it effectively.

  • It includes knowledge of the principles, theories, and concepts related to the field.

  • Technical knowledge also encompasses practical skills and hands-on experience in using tools, equipment, and techniques ...read more

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Q37. what beer's law ?

Ans.

Beer's law, also known as the Beer-Lambert law, describes the relationship between the concentration of a solute in a solution and the amount of light absorbed by the solution.

  • Beer's law states that the absorbance of a solution is directly proportional to the concentration of the solute.

  • It is commonly used in spectrophotometry to determine the concentration of a substance in a solution.

  • The equation for Beer's law is A = εcl, where A is the absorbance, ε is the molar absorptiv...read more

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Q38. Chromatography Techniques

Ans.

Chromatography techniques are used to separate and analyze mixtures of compounds based on their different properties.

  • Chromatography involves a stationary phase and a mobile phase.

  • Different compounds in the mixture interact differently with the stationary phase, leading to separation.

  • Examples include gas chromatography, liquid chromatography, and thin-layer chromatography.

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Q39. How to resolve Technical query in APIs quality.

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Q40. 1. How to start HPLC method development

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Q41. What was your best selling product?

Ans.

My best selling product was the XYZ model, which had a sleek design and advanced features.

  • The XYZ model had a unique selling proposition that set it apart from competitors.

  • Customers appreciated the product's ease of use and reliability.

  • Marketing efforts focused on highlighting the product's key features and benefits.

  • Sales team received extensive training on the product to effectively communicate its value to customers.

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Q42. Q) why do we use water as major part of utility.

Ans.

Water is used as a major part of utility due to its abundance, versatility, cost-effectiveness, and environmentally friendly properties.

  • Abundance: Water is readily available in nature and can be easily sourced for various industrial processes.

  • Versatility: Water can be used for a wide range of applications such as cooling, cleaning, and as a solvent.

  • Cost-effectiveness: Water is relatively inexpensive compared to other utilities, making it a cost-effective choice for industrial...read more

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Q43. Normality molarity different

Ans.

Normality and molarity are different units of concentration in chemistry.

  • Normality is the number of equivalents of a substance in a liter of solution, while molarity is the number of moles of a substance in a liter of solution.

  • Normality is used in acid-base reactions, while molarity is used in general chemistry calculations.

  • For example, a 1M solution of HCl has a normality of 1N, but a 1M solution of NaCl has a normality of 2N.

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Q44. 1.types of reactor

Ans.

Reactors are vessels used in chemical processes to contain and control reactions.

  • Batch reactor: used for small-scale production and testing

  • Continuous stirred-tank reactor (CSTR): used for continuous production

  • Packed bed reactor: used for catalytic reactions

  • Fluidized bed reactor: used for gas-solid reactions

  • Fixed bed reactor: used for heterogeneous reactions

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Q45. What is CSV and its models. What is Agile, V- Model Periodic Review.

Ans.

CSV stands for Computer System Validation, which is a process used to ensure that a computerized system is fit for its intended use. Agile and V-Model are software development methodologies.

  • CSV involves documenting and testing the system to ensure it meets regulatory requirements.

  • Agile is a flexible and iterative approach to software development, focusing on delivering working software frequently.

  • V-Model is a software development model that emphasizes testing at each stage of...read more

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Q46. What is SS reactor ?

Ans.

SS reactor is a type of reactor made of stainless steel used in chemical and pharmaceutical industries.

  • SS reactor is used for mixing, heating, and cooling of chemicals and pharmaceuticals.

  • It is made of stainless steel to prevent corrosion and contamination.

  • SS reactors are commonly used in the production of medicines, vaccines, and other pharmaceutical products.

  • They are also used in the production of chemicals such as polymers, resins, and adhesives.

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Q47. What is the difference between windows client and server

Ans.

Windows client is used by end-users for personal computing tasks, while Windows server is used for hosting services and applications.

  • Windows client is designed for individual users to perform personal computing tasks.

  • Windows server is designed to host services, applications, and data for multiple users or clients.

  • Windows client typically has a graphical user interface (GUI) for easy navigation and interaction.

  • Windows server is optimized for performance, reliability, and secur...read more

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Q48. What is the avagadros number?

Ans.

Avogadro's number is a constant representing the number of constituent particles (usually atoms or molecules) in one mole of a substance.

  • Avogadro's number is approximately 6.022 x 10^23.

  • It is named after Italian scientist Amedeo Avogadro.

  • It is used in chemistry to relate the mass of a substance to the number of atoms or molecules it contains.

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Q49. What is the difference between MTTR and MTBF?

Ans.

MTTR is the average time to repair a failed system, while MTBF is the average time between failures.

  • MTTR measures downtime and repair time, while MTBF measures reliability and uptime.

  • MTTR is a measure of how quickly a system can be restored after a failure, while MTBF is a measure of how long a system can operate without failing.

  • MTTR is typically used to evaluate maintenance performance, while MTBF is used to evaluate system design and reliability.

  • For example, if a system has...read more

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Q50. What is GLR?

Ans.

GLR stands for Generalized Likelihood Ratio.

  • GLR is a statistical method used for hypothesis testing.

  • It compares the likelihood of two different hypotheses to determine which one is more likely to be true.

  • GLR is commonly used in fields such as signal processing, machine learning, and bioinformatics.

  • For example, GLR can be used to detect anomalies in data or to classify different types of signals.

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Q51. Tff system introduction

Ans.

The Tff system is a new technology introduced to streamline operations and improve efficiency.

  • The Tff system automates manual processes to save time and reduce errors

  • It integrates data from multiple sources for better decision-making

  • Training and support are provided to ensure successful implementation

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Q52. What is chemistry?

Ans.

Chemistry is the study of matter, its properties, composition, and interactions.

  • Chemistry involves understanding the structure and behavior of atoms and molecules.

  • It explores how substances react with each other and transform into new substances.

  • Chemistry is essential in fields like pharmaceuticals, food science, and environmental science.

  • Examples include studying the properties of elements on the periodic table and analyzing chemical reactions in a laboratory.

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Q53. MSDS and SDS explanations and difference.

Ans.

MSDS and SDS are documents that provide information on the properties of chemicals and how to safely handle them.

  • MSDS stands for Material Safety Data Sheet and provides detailed information about a chemical's properties, hazards, and safe handling procedures.

  • SDS stands for Safety Data Sheet and is a standardized format for providing information on a chemical's properties, hazards, and safe handling procedures.

  • MSDS are being replaced by SDS under the Globally Harmonized System...read more

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Q54. Functional work with cross functional teams

Ans.

Working with cross functional teams to achieve common goals and objectives.

  • Collaborating with team members from different departments to share expertise and resources

  • Communicating effectively to ensure everyone is on the same page

  • Resolving conflicts and addressing challenges that arise from differing perspectives

  • Aligning individual goals with team goals to drive success

  • Example: Leading a project with members from marketing, sales, and product development to launch a new produ...read more

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Q55. What types of hazardous chemicals handled

Ans.

Various hazardous chemicals are handled, including corrosive, flammable, toxic, and reactive substances.

  • Corrosive chemicals such as sulfuric acid and hydrochloric acid

  • Flammable chemicals like gasoline and acetone

  • Toxic chemicals including mercury and lead

  • Reactive substances such as sodium and potassium

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Q56. What payment term can be follow.

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Q57. How many types of boilers

Ans.

There are several types of boilers used in various industries and applications.

  • There are four main types of boilers: fire-tube, water-tube, electric, and biomass.

  • Fire-tube boilers are commonly used in steam locomotives and industrial plants.

  • Water-tube boilers are used in power stations and large industrial settings.

  • Electric boilers are used for heating purposes in residential and commercial buildings.

  • Biomass boilers use organic materials like wood chips or agricultural waste ...read more

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Q58. 3. Audit trails 4. Deviation vs incident 5. OOS

Ans.

Audit trails, deviations vs incidents, and OOS are important concepts in quality management.

  • Audit trails are chronological records that provide documented evidence of activities performed in a system.

  • Deviations are unplanned events that do not meet specifications, while incidents are unexpected events that may or may not impact product quality.

  • OOS (Out of Specification) results occur when test results fall outside established acceptance criteria.

  • Proper documentation and inves...read more

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Q59. Other engineering action taken

Ans.

Implemented various engineering solutions to address issues and improve efficiency.

  • Developed new software tools to streamline processes

  • Implemented automation systems to increase productivity

  • Optimized equipment layouts to improve workflow

  • Utilized predictive maintenance techniques to reduce downtime

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Q60. What accridation you work.

Ans.

I work with the accreditation of scientific research and laboratories.

  • I am responsible for ensuring that research and laboratory practices meet the required standards and guidelines.

  • I review and evaluate research protocols, methodologies, and data to ensure accuracy and compliance.

  • I collaborate with regulatory bodies and organizations to develop and implement accreditation programs.

  • I conduct audits and inspections to assess compliance with accreditation standards.

  • I provide gu...read more

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Q61. Q) Condensor area calculation and drying time..

Ans.

Condenser area calculation is based on heat transfer requirements and drying time depends on factors like temperature, humidity, and airflow.

  • Calculate condenser area based on heat transfer requirements and desired cooling capacity

  • Consider factors like temperature, humidity, and airflow when determining drying time

  • Use formulas such as Q = U * A * deltaT for heat transfer calculations

  • Optimize condenser design to maximize efficiency and minimize drying time

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Q62. Brief about HPLC

Ans.

HPLC stands for High Performance Liquid Chromatography, a technique used to separate, identify, and quantify components in a mixture.

  • HPLC involves a stationary phase, mobile phase, and a detector.

  • It is commonly used in pharmaceutical, environmental, and food industries.

  • HPLC can separate complex mixtures based on differences in polarity, size, and charge of components.

  • Examples of applications include drug analysis, pesticide detection, and amino acid quantification.

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Q63. How to develop the business.

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Q64. What is CLIA

Ans.

CLIA stands for Clinical Laboratory Improvement Amendments.

  • CLIA is a set of federal regulations in the United States that establish quality standards for laboratory testing.

  • It applies to all clinical laboratories that test human specimens for health assessment or to diagnose, prevent, or treat disease.

  • CLIA aims to ensure accurate and reliable laboratory testing results by setting standards for personnel qualifications, quality control, proficiency testing, and more.

  • It categor...read more

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Q65. What is qc

Ans.

QC stands for Quality Control.

  • QC is a process used to ensure that products or services meet specified requirements and standards.

  • It involves monitoring and testing products or services to identify any defects or deviations from the desired quality.

  • QC aims to prevent or minimize errors, defects, or variations in products or services.

  • It can include activities such as inspections, testing, sampling, and data analysis.

  • QC is commonly used in industries such as manufacturing, healt...read more

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Q66. How to handle things

Ans.

Handling things involves prioritizing tasks, delegating responsibilities, and problem-solving effectively.

  • Prioritize tasks based on urgency and importance

  • Delegate responsibilities to team members based on their strengths and workload

  • Problem-solve by identifying the root cause and finding solutions

  • Communicate clearly and effectively with team members and stakeholders

  • Stay organized and maintain a positive attitude

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Q67. How to design vacuum pump

Ans.

Designing a vacuum pump involves selecting the appropriate type, determining the required flow rate and pressure, and sizing the components.

  • Choose the type of vacuum pump based on the application (e.g. rotary vane, diaphragm, scroll, etc.)

  • Determine the required flow rate and pressure for the system

  • Size the components, including the pump, motor, and piping, to meet the flow rate and pressure requirements

  • Consider factors such as maintenance, noise level, and energy efficiency w...read more

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Q68. Explain aex with example?

Ans.

AEX stands for Average Execution Time, a metric used to measure the average time taken to execute a process or task.

  • AEX is calculated by summing up the total execution time of a process and dividing it by the number of executions.

  • For example, if a process takes 10 seconds to execute and it is run 5 times, the AEX would be 10/5 = 2 seconds.

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Q69. Give an example of AEX?

Ans.

AEX stands for Amsterdam Exchange, a stock exchange in the Netherlands.

  • AEX is a stock market index composed of the 25 most actively traded Dutch companies on the Amsterdam Exchange.

  • It is often used as a benchmark for the Dutch stock market.

  • Examples of companies included in the AEX index are Royal Dutch Shell, ASML, and Unilever.

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Q70. What is quality assurance

Ans.

Quality assurance is the process of ensuring that products or services meet specified requirements and standards.

  • Quality assurance involves establishing processes to prevent defects in products or services

  • It focuses on continuous improvement and monitoring of processes

  • Quality assurance includes activities such as audits, inspections, and testing

  • Examples include software testing to ensure a program functions correctly and food safety checks to prevent contamination

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Q71. What is line clearance

Ans.

Line clearance is the process of ensuring that a production line or area is free from any previous materials, tools, or equipment before starting a new process.

  • Line clearance involves visually inspecting the production area to ensure it is clean and free of any leftover materials.

  • It also involves verifying that all necessary tools and equipment are in place for the new process.

  • Line clearance helps prevent contamination and mix-ups during production.

  • Examples: cleaning a packag...read more

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Q72. What is data integrety

Ans.

Data integrity refers to the accuracy, consistency, and reliability of data throughout its lifecycle.

  • Ensures data is accurate and reliable

  • Prevents unauthorized access or changes to data

  • Maintains consistency of data across systems

  • Examples: checksums, encryption, access controls

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Q73. What is reaction kinetics

Ans.

Reaction kinetics is the study of rates at which chemical reactions occur.

  • Reaction kinetics involves studying the factors that affect the speed of a chemical reaction.

  • It includes determining the reaction mechanism, rate laws, and reaction rates.

  • Examples of factors affecting reaction kinetics include temperature, concentration, and catalysts.

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Q74. Quality output from the application

Ans.

Quality output from the application is crucial for customer satisfaction and business success.

  • Implement thorough testing procedures to ensure the application functions correctly

  • Regularly gather feedback from users to identify areas for improvement

  • Utilize quality assurance tools and techniques to monitor and maintain high standards

  • Train and support development team to prioritize quality in all aspects of their work

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Q75. Van dee meter equation

Ans.

The Van Dee meter equation is used to calculate the velocity of a fluid flow in a pipe.

  • The Van Dee meter equation is based on the principle of conservation of mass and energy.

  • It takes into account the pressure difference between two points in a pipe, the density of the fluid, and the pipe diameter.

  • The equation is typically used in fluid mechanics and engineering applications to determine flow rates.

  • Example: V = (2*(P1 - P2) / ρ) / (1 - (d2^4 / d1^4))^(1/2), where V is the vel...read more

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Q76. How do you passage cells

Ans.

Passaging cells involves detaching cells from a culture vessel, diluting them, and transferring them to a new vessel to allow for continued growth.

  • Use a sterile technique to detach cells from the culture vessel

  • Collect the cells in a centrifuge tube and centrifuge to pellet the cells

  • Resuspend the cells in fresh media and calculate the appropriate dilution factor

  • Transfer the diluted cells to a new culture vessel and incubate for continued growth

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Q77. Types of reactors, agitators handled

Ans.

Various types of reactors and agitators are handled depending on the specific requirements of the project.

  • Types of reactors include batch reactors, continuous stirred tank reactors (CSTR), plug flow reactors, and fluidized bed reactors.

  • Types of agitators include paddle agitators, anchor agitators, turbine agitators, and propeller agitators.

  • Selection of reactors and agitators is based on factors such as reaction kinetics, heat transfer requirements, and mixing efficiency.

  • Exper...read more

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Q78. What is cell culture

Ans.

Cell culture is the process of growing cells outside of their natural environment under controlled conditions.

  • Cells are typically grown in a sterile environment with specific nutrients and conditions to support their growth

  • Cell culture is commonly used in research, drug development, and biotechnology

  • Examples include growing bacteria in a petri dish or culturing mammalian cells in a flask

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Q79. How to build a team

Ans.

Building a team involves clear communication, setting goals, fostering collaboration, and providing support.

  • Clearly define roles and responsibilities for each team member.

  • Set achievable goals and provide regular feedback to track progress.

  • Encourage open communication and collaboration among team members.

  • Provide necessary resources and support to help team members succeed.

  • Lead by example and create a positive work environment.

  • Recognize and reward team achievements to boost mor...read more

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Q80. What is the API?

Ans.

API stands for Application Programming Interface. It is a set of rules and protocols that allows different software applications to communicate with each other.

  • APIs define the methods and data formats that applications can use to request and exchange information.

  • They allow developers to access the functionality of a software application or service without needing to understand its internal workings.

  • Examples of APIs include Google Maps API for integrating maps into a website, ...read more

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Q81. Tools to evaluate training

Ans.

Various tools can be used to evaluate training effectiveness, such as surveys, assessments, observations, and feedback sessions.

  • Surveys: Gather feedback from trainees about the training content, delivery, and overall experience.

  • Assessments: Test trainees on their knowledge and skills before and after the training to measure improvement.

  • Observations: Observe trainees in action to see how well they are applying the training in real-world scenarios.

  • Feedback sessions: Have discus...read more

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Q82. What is scale-up

Ans.

Scale-up is the process of increasing the production capacity of a system or process.

  • Scale-up involves transferring a process from a small scale to a larger scale.

  • Factors such as equipment size, operating conditions, and material properties need to be considered during scale-up.

  • Examples of scale-up include increasing the batch size of a chemical reaction or transitioning from a lab-scale production to a pilot plant or full-scale production.

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Q83. What is role of

Ans.

The role of a chemist is to study the composition, properties, and reactions of substances.

  • Conducting experiments to analyze chemical compounds

  • Developing new products or processes

  • Ensuring safety and compliance with regulations

  • Collaborating with other scientists and researchers

  • Providing expertise in areas such as environmental protection or pharmaceuticals

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Q84. Explain ca19.9 test

Ans.

CA19-9 test is a blood test used to measure the levels of CA19-9 antigen, which can be elevated in certain cancers.

  • CA19-9 test measures the levels of CA19-9 antigen in the blood

  • It is primarily used to aid in the diagnosis and monitoring of pancreatic, liver, and gastrointestinal cancers

  • Elevated CA19-9 levels can also be seen in non-cancerous conditions like pancreatitis and liver disease

  • The test is not specific to a particular type of cancer and should be used in conjunction ...read more

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Q85. What is six Sigma

Ans.

Six Sigma is a data-driven methodology used to improve processes by reducing defects and variations.

  • Six Sigma aims to achieve near perfection in the products or services delivered by a company.

  • It focuses on identifying and eliminating causes of defects and errors in a process.

  • Six Sigma uses statistical tools and techniques to measure and analyze process performance.

  • The goal of Six Sigma is to reduce variation and improve quality, leading to increased customer satisfaction and...read more

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Q86. What is ALCOA ++

Ans.

ALCOA++ is a set of principles for data integrity in pharmaceutical manufacturing, including Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, and Available.

  • ALCOA++ is an extension of the ALCOA principles, which are used to ensure data integrity in regulated industries.

  • It includes additional criteria such as Consistent, Enduring, and Available to further enhance data integrity.

  • For example, data should be consistent across all records,...read more

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Q87. Calculate the coloumn volume

Ans.

Column volume can be calculated by multiplying the cross-sectional area of the column by its height.

  • Calculate the cross-sectional area of the column (e.g. if the column is cylindrical, use the formula A = πr^2)

  • Measure the height of the column

  • Multiply the cross-sectional area by the height to get the column volume

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Q88. ICH guidelines

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Q89. Chemistry of indicator

Ans.

Indicators are substances that change color in response to changes in pH levels, helping to determine the acidity or alkalinity of a solution.

  • Indicators are typically weak acids or bases that dissociate in water and change color based on the concentration of H+ ions.

  • Common indicators include phenolphthalein, litmus, and bromothymol blue.

  • The color change of an indicator is due to a shift in the equilibrium between the acidic and basic forms of the indicator molecule.

  • Indicators...read more

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Q90. Defined Amino acid?

Ans.

Amino acids are organic compounds that serve as the building blocks of proteins.

  • Amino acids are the monomers that make up proteins.

  • They contain an amino group (-NH2), a carboxyl group (-COOH), and a side chain.

  • There are 20 standard amino acids that are commonly found in proteins.

  • Amino acids can be classified as essential, nonessential, or conditional depending on the body's ability to synthesize them.

  • Examples of amino acids include alanine, glycine, leucine, and phenylalanine...read more

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