Syngene International Interview Questions, Process, and Tips

Q1. What reagent used for acid -amine coupling?
Ans. 
The reagent used for acid-amine coupling is typically carbodiimides.
• Carbodiimides are commonly used reagents for acid-amine coupling reactions.

• Examples of carbodiimides include EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide) and DIC (diisopropylcarbodiimide).
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Q2. How to quench pyrophoric reagent?
Ans. 
Pyrophoric reagents can be quenched by using appropriate quenching agents.
• Use a non-reactive quenching agent such as water, alcohol, or mineral oil.

• Add the quenching agent slowly to the pyrophoric reagent while stirring gently.

• Dispose of the quenched mixture according to safety guidelines.

• Always wear appropriate personal protective equipment when handling pyrophoric reagents.
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Q1. How much f0 value should be in autoclave?
Ans. 
The f0 value in autoclave should typically be at least 8 to ensure proper sterilization.
• The f0 value is a measure of the lethality of a sterilization process, taking into account both time and temperature.

• A minimum f0 value of 8 is commonly recommended for autoclaves to ensure proper sterilization.

• Factors such as the type of load being sterilized and the desired level of sterility may influence the required f0 value.
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Q2. In tunnel depyrogenation zone vials how much time should be sterilization
Ans. 
The sterilization time in tunnel depyrogenation zone vials varies depending on the specific process and equipment used.
• Sterilization time can range from a few minutes to over an hour, depending on the temperature and method of sterilization.

• Factors such as the type of vials, the level of contamination, and the desired sterility assurance level also impact the sterilization time.

• For example, a tunnel depyrogenation proc...read more
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Q3. Why we are Doing VLT in autoclave
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Q4. Why we are doing In autoclave bowie test
Ans. 
Autoclave Bowie test is conducted to ensure the sterilization process is effective and meets industry standards.
• To ensure that the autoclave is functioning properly and effectively sterilizing equipment

• To meet industry standards and regulations for sterilization processes

• To verify that the autoclave is killing all microorganisms and spores

• To prevent contamination and ensure the safety of patients and staff
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Q5. What will ensure in bowie test
Ans. 
Ensuring proper testing procedures and accurate results in the bowie test.
• Properly calibrating equipment before conducting the test

• Following standardized testing protocols

• Ensuring the test samples are handled and stored correctly

• Regularly maintaining and servicing testing equipment

• Training staff on how to conduct the test accurately
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