Zydus Lifesciences Analytical Scientist Interview Questions and Answers

Chromatography is a technique used to separate and analyze mixtures of chemicals based on their properties.

• Chromatography involves passing a mixture through a stationary phase, which separates the components based on their interactions with the stationary phase and mobile phase.

• Different types of chromatography include gas chromatography, liquid chromatography, and thin-layer chromatography.

• It is widely used in various...read more

Analysis is the process of examining data or information to uncover insights, patterns, and trends.

• Analysis involves breaking down complex information into smaller components for better understanding.

• It helps in making informed decisions based on the findings.

• Examples include financial analysis to assess company performance, data analysis to identify trends in customer behavior, and market analysis to understand indust

Current approaches on nitrosamine impurities

• Analytical techniques such as LC-MS and GC-MS are commonly used to detect and quantify nitrosamine impurities in pharmaceuticals

• Regulatory agencies have set limits on the acceptable levels of nitrosamine impurities in drugs

• Manufacturers are required to conduct risk assessments and implement control measures to prevent nitrosamine contamination

• Some common approaches to mitigat...read more

Quadrapoles are used in mass spectrometry to filter ions based on their mass-to-charge ratio.

• Quadrapoles use radio frequency and direct current voltages to selectively filter ions.

• They are composed of four parallel rods that create a quadrupole electric field.

• Ions with a specific mass-to-charge ratio will oscillate within the field and pass through the filter.

• Quadrapoles are commonly used in tandem mass spectrometry fo

Q trap system is a type of mass spectrometer that uses triple quadrupole technology with an added linear ion trap for enhanced sensitivity and selectivity.

• Q trap system is used for targeted quantification and identification of small molecules in complex matrices.

• It combines the benefits of triple quadrupole technology with an added linear ion trap for enhanced sensitivity and selectivity.

• It allows for multiple reaction...read more