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Natco Pharma

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30+ Natco Pharma Interview Questions and Answers

Updated 2 Mar 2025

Q1. What are all QMS tool used , ple explain briefly,and what are all documents mainten during production

Ans.

Various QMS tools such as FMEA, Control Charts, and 5S are used in production. Documents maintained include SOPs, work instructions, and production logs.

  • QMS tools used in production include Failure Mode and Effects Analysis (FMEA), Control Charts, and 5S methodology

  • Documents maintained during production may include Standard Operating Procedures (SOPs), work instructions, production logs, and quality records

  • FMEA is used to identify and prioritize potential failure modes in a p...read more

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Q2. 1. Reason for leaving previous organisation 2. Package finalization 3. How quickly can you join. 4. In future if we relocate you will you be able to relocate. 5. Closure.

Ans.

Answering questions related to previous organization, package, availability, relocation, and closure.

  • Left previous organization for better growth opportunities

  • Package can be discussed based on the job role and responsibilities

  • Can join within 2 weeks of receiving the offer letter

  • Willing to relocate if required for the job

  • Thank you for considering me for the position

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Q3. What is cmax ,tmax? What do u know about natco pharma?

Ans.

Cmax and Tmax are pharmacokinetic parameters used to describe the absorption of a drug. Natco Pharma is an Indian pharmaceutical company.

  • Cmax is the maximum concentration of a drug in the bloodstream after administration.

  • Tmax is the time it takes for the drug to reach its maximum concentration in the bloodstream.

  • Natco Pharma is a leading Indian pharmaceutical company that specializes in the development and manufacture of generic drugs.

  • The company has a strong presence in the ...read more

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Q4. How do you reposition a Brand in the Market?

Ans.

Repositioning a brand involves analyzing market trends, identifying target audience, creating a new brand image, and implementing strategic marketing campaigns.

  • Conduct market research to understand current market trends and consumer preferences.

  • Identify the target audience and their needs to tailor the brand positioning accordingly.

  • Create a new brand image or message that resonates with the target audience.

  • Develop strategic marketing campaigns to communicate the repositioned ...read more

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Q5. What type of cooling system used in compression area

Ans.

The type of cooling system used in compression area is typically a water-cooled system.

  • Water-cooled systems are commonly used in compression areas to dissipate heat generated during compression process

  • Water-cooled systems use water as a coolant to absorb heat and maintain optimal operating temperatures

  • Examples of water-cooled systems include water jackets surrounding the compression chamber or water-cooled intercoolers

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Q6. What type decesions taking in abnormal conditions

Ans.

In abnormal conditions, decisions must be made quickly and effectively to ensure safety and minimize damage.

  • Assess the situation and identify potential risks

  • Consult with team members and experts

  • Implement emergency protocols

  • Communicate clearly and effectively with all parties involved

  • Document the incident and actions taken for future reference

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Q7. What do you know about hepatology Indian market ?

Ans.

The hepatology Indian market focuses on liver diseases and treatments in India.

  • Hepatology in India is a growing field due to the high prevalence of liver diseases such as hepatitis B and C, fatty liver disease, and cirrhosis.

  • The market includes pharmaceutical companies offering medications for liver diseases, hospitals with specialized liver care units, and research institutions studying liver health in the Indian population.

  • Liver transplants are also a significant part of th...read more

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Q8. Explain last method validation you handled

Ans.

Validated a new HPLC method for testing impurities in pharmaceutical products

  • Reviewed method development protocol and validation plan

  • Executed validation experiments according to ICH guidelines

  • Analyzed data and prepared validation report

  • Ensured method was robust, accurate, and precise

  • Collaborated with cross-functional teams for successful validation

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Q9. Impeller and chopper speed at slow and high rpm in RMG

Ans.

Impeller and chopper speed in RMG vary at slow and high rpm for different mixing purposes.

  • Impeller speed is typically slower at low rpm for gentle mixing of ingredients.

  • Chopper speed is usually higher at high rpm for more intense mixing and size reduction of particles.

  • The combination of impeller and chopper speeds at different rpm levels allows for versatile mixing capabilities in RMG.

  • For example, in a high shear granulator, the impeller speed may be lower at slow rpm for ini...read more

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Q10. Out of Specification flow as per fda

Ans.

Out of Specification flow as per FDA refers to the process of handling test results that fall outside of predetermined acceptance criteria.

  • Investigate the root cause of the out of specification result

  • Document the investigation process and findings

  • Evaluate the impact on product quality and patient safety

  • Implement corrective and preventive actions to prevent recurrence

  • Communicate with relevant stakeholders including FDA if necessary

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Q11. What is the beer Lambert law

Ans.

The Beer-Lambert law relates the attenuation of light to the properties of the material through which the light is traveling.

  • Also known as Beer's law or Lambert-Beer law

  • Used in chemistry and physics to measure the concentration of a substance in a solution

  • States that the absorbance of a substance is directly proportional to its concentration and the path length of the light through the material

  • A = εcl, where A is absorbance, ε is the molar absorptivity, c is the concentration...read more

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Q12. End point determination of RMG, FBD

Ans.

End point determination of RMG, FBD involves identifying the point where the reaction mixture changes color or behavior.

  • Use visual inspection to determine the end point of the reaction mixture.

  • Monitor changes in color, turbidity, or other physical properties to identify the end point.

  • Utilize analytical techniques such as titration or spectroscopy for more accurate end point determination.

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Q13. What is your feature goals

Ans.

My feature goals are to continuously improve my technical skills, contribute to the success of the company, and become a valuable asset to the team.

  • Continuously improve technical skills through training and self-study

  • Contribute to the success of the company by identifying and implementing cost-saving measures

  • Become a valuable asset to the team by collaborating with colleagues and sharing knowledge

  • Develop innovative solutions to complex engineering problems

  • Stay up-to-date with...read more

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Q14. why Natco ? what is the major interest here

Ans.

Natco is a leading pharmaceutical company known for its focus on affordable and high-quality generic medicines.

  • Natco has a strong reputation for providing affordable generic medicines to patients worldwide.

  • The company is known for its commitment to quality and innovation in the pharmaceutical industry.

  • Natco's focus on research and development has led to the development of a wide range of high-quality generic drugs.

  • The company's global presence and partnerships with other phar...read more

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Q15. How much do you know about market and technical

Ans.

I have a strong understanding of both market and technical aspects.

  • I have experience conducting market research to identify trends and opportunities.

  • I am proficient in analyzing technical specifications and requirements.

  • I have successfully launched products that required a deep understanding of both market demands and technical capabilities.

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Q16. Calibration of hplc

Ans.

Calibration of HPLC involves adjusting the instrument to ensure accurate and reliable results.

  • Calibration is necessary to maintain accuracy and precision in HPLC analysis.

  • Calibration involves adjusting parameters such as flow rate, detector sensitivity, and column efficiency.

  • Standard solutions with known concentrations are used to calibrate the instrument.

  • Calibration should be performed regularly to ensure consistent results.

  • Documentation of calibration procedures and results...read more

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Q17. What is definition of aseptic area?

Ans.

An aseptic area is a controlled environment where the risk of contamination is minimized to ensure sterility.

  • Aseptic areas are commonly found in pharmaceutical manufacturing facilities, hospitals, and research laboratories.

  • Strict protocols and procedures are followed to maintain cleanliness and prevent microbial contamination.

  • Examples of aseptic areas include clean rooms, laminar flow hoods, and isolators.

  • Workers in aseptic areas must wear sterile clothing, use disinfectants,...read more

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Q18. Explain about cleaning validation

Ans.

Cleaning validation is the process of ensuring that cleaning procedures effectively remove residues from equipment to prevent cross-contamination.

  • Cleaning validation is essential in industries like pharmaceuticals, food production, and cosmetics to ensure product quality and safety.

  • It involves establishing cleaning procedures, setting acceptance criteria, and conducting tests to verify cleanliness.

  • Analytical techniques such as swab testing, rinse sampling, and visual inspecti...read more

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Q19. What do you learn from chemistry

Ans.

Chemistry teaches us about the composition, structure, properties, and changes of matter.

  • Understanding the fundamental principles of chemistry helps in predicting how substances will interact with each other.

  • Chemistry provides insights into the behavior of atoms and molecules, leading to the development of new materials and technologies.

  • Knowledge of chemistry is essential in fields such as medicine, environmental science, and engineering.

  • Chemistry helps in understanding the n...read more

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Q20. How Much Pharma Sales Experience?

Ans.

I have 3 years of experience in pharmaceutical sales.

  • I have worked as a medical representative for 3 years.

  • During my tenure, I have successfully promoted and sold various pharmaceutical products.

  • I have a good understanding of the pharmaceutical industry and its regulations.

  • I have developed strong relationships with healthcare professionals and key decision-makers.

  • I am constantly updating my knowledge and skills to stay ahead in the competitive market.

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Q21. How SFM works in FBD

Ans.

SFM (Structured Flow Modeling) in FBD (Functional Block Diagram) is a method used to represent the behavior of a system through interconnected blocks.

  • SFM breaks down a system into functional blocks, each representing a specific function or operation.

  • The blocks are interconnected to show the flow of information or signals between them.

  • It helps in understanding the overall system behavior and identifying potential issues or improvements.

  • For example, in a control system, SFM can...read more

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Q22. Explain about maco calculation

Ans.

MACO calculation is used to determine the maximum allowable carryover of a substance in a cleaning process.

  • MACO stands for Maximum Allowable Carryover

  • It is calculated based on the acceptable daily intake (ADI) of the substance and the worst-case scenario for residue on equipment

  • MACO calculation helps ensure that cleaning processes are effective in removing residues to prevent cross-contamination

  • Example: If the ADI of a substance is 10 mg/day and the worst-case residue on equi...read more

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Q23. Explain about heat load

Ans.

Heat load refers to the amount of heat energy that needs to be removed or added to a space to maintain a desired temperature.

  • Heat load is calculated based on factors such as the size of the space, insulation, number of occupants, equipment, and climate conditions.

  • Examples of heat load include solar heat gain through windows, heat generated by lighting and equipment, and heat loss through walls and roofs.

  • Understanding heat load is crucial for designing HVAC systems to effectiv...read more

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Q24. What is the limits of NVPC

Ans.

The limits of NVPC refer to the maximum number of virtual processors that can be assigned to a virtual machine in a Hyper-V environment.

  • NVPC stands for Non-Uniform Memory Access (NUMA) Virtual Processor Cap.

  • The limits of NVPC vary depending on the version of Hyper-V being used.

  • For example, in Hyper-V on Windows Server 2016, the maximum NVPC limit is 240.

  • Exceeding the NVPC limit can lead to performance issues and resource contention.

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Q25. Dimension less Numbers

Ans.

Dimensionless numbers are used in fluid mechanics to characterize the behavior of fluids in various flow situations.

  • Dimensionless numbers are ratios of physical properties that have no units.

  • They are used to simplify equations and make them applicable to different scales and systems.

  • Examples include Reynolds number, Froude number, and Mach number.

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Q26. Process of granulation

Ans.

Granulation is a process in which small particles are formed by agglomerating powder particles.

  • Granulation involves the binding of powder particles to form larger particles.

  • It can be achieved through methods like wet granulation, dry granulation, and direct compression.

  • Examples include pharmaceutical tablets, where granulation is used to improve flow properties and compressibility of the powder.

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Q27. How to asset transfer?

Ans.

Asset transfer involves documenting the transfer of ownership or possession of assets from one party to another.

  • Ensure proper documentation is completed for the transfer

  • Update inventory records to reflect the transfer

  • Verify the condition of the asset before and after transfer

  • Obtain necessary approvals for the transfer

  • Communicate the transfer to relevant stakeholders

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Q28. What is HIV,HBV, ?

Ans.

HIV and HBV are viruses that can cause serious infections in humans.

  • HIV is a virus that attacks the immune system and can lead to AIDS.

  • HBV is a virus that attacks the liver and can cause liver disease.

  • Both viruses can be transmitted through blood, semen, and other bodily fluids.

  • Prevention measures include safe sex practices, avoiding sharing needles, and getting vaccinated for HBV.

  • Treatment for HIV includes antiretroviral therapy, while treatment for HBV includes antiviral me...read more

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Q29. Explain about gmp

Ans.

GMP stands for Good Manufacturing Practices, which are guidelines and regulations set by regulatory agencies to ensure the quality and safety of products.

  • GMP is a set of guidelines and regulations that ensure products are consistently produced and controlled according to quality standards.

  • It covers all aspects of production, including the facilities, equipment, personnel, and processes.

  • Examples of GMP requirements include proper documentation, sanitation practices, and qualit...read more

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Q30. Whic ever field ur in

Ans.

The question is not clear and lacks proper grammar.

  • The question is incomplete and lacks context.

  • It is difficult to provide a descriptive answer without understanding the specific field or topic being referred to.

  • Without more information, it is not possible to give examples or pointers.

  • The question seems to have grammatical errors and is unclear.

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Q31. What is the diulot solution

Ans.

Diluot solution is a liquid used to dilute or dissolve substances for various chemical processes.

  • Diluot solution is commonly used in laboratories for diluting samples or reagents.

  • It can also be used to dissolve solid substances for easier handling or analysis.

  • The composition of diluot solution can vary depending on the specific application.

  • Examples of diluot solutions include water, ethanol, and various buffer solutions.

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Q32. What is Pharmacovigilance?

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Q33. Difine the diulot solution

Ans.

A dilute solution is a solution that has a low concentration of solute compared to the solvent.

  • Dilute solutions have a small amount of solute dissolved in a large amount of solvent.

  • They are commonly used in chemistry experiments to create solutions with specific concentrations.

  • Dilute solutions can be made by adding more solvent to a concentrated solution.

  • The concentration of a dilute solution is usually expressed in terms of molarity or percentage.

  • Examples of dilute solutions...read more

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