Zydus Lifesciences Interview Questions, Process, and Tips

My ideal office environment is one that is organized, collaborative, and supportive.

• Open communication among team members

• Clear expectations and goals set by management

• Comfortable workspaces with natural light

• Opportunities for professional development and growth

• Supportive and inclusive company culture

I have 5 years of experience working in various departments within the company, including customer service, sales, and operations.

• Started as a customer service representative and quickly moved up to a sales role

• Managed a team of 10 employees in the operations department

• Implemented new strategies to improve customer satisfaction and increase sales

• Collaborated with different departments to streamline processes and improv

ALCOA stands for Attributable, Legible, Contemporaneous, Original, and Accurate. Calibration of instruments is crucial in the manufacturing process to ensure accurate and reliable measurements.

• ALCOA principles ensure data integrity in manufacturing processes

• Instrument calibration is necessary to maintain accuracy and reliability

• Regular calibration schedules should be established and followed

• Documentation of calibration...read more

Die fill depth is a critical parameter of a compression machine.

• Die fill depth affects tablet weight and hardness

• Proper die fill depth ensures uniform tablet thickness

• Incorrect die fill depth can lead to capping or lamination issues

• Die fill depth is controlled by adjusting the fill cam or fill shoe

• Examples: 10-15 mm for standard tablets, 5-8 mm for mini tablets

Process Validation is the documented evidence that a process consistently produces a product meeting its predetermined specifications and quality attributes.

• Process Validation is a requirement in industries such as pharmaceuticals, medical devices, and food production.

• It involves establishing documented evidence that a process is capable of consistently producing a product that meets its specifications.

• Validation activ...read more

Exhibit batches are used for stability studies and regulatory submissions, while PPQ batches are used for process validation.

• Exhibit batches are manufactured for stability studies and regulatory submissions.

• PPQ (Process Performance Qualification) batches are manufactured for process validation.

• Exhibit batches are typically larger in size compared to PPQ batches.

• Exhibit batches are used to demonstrate the product's stab...read more

Parameters used in tablet manufacturing include formulation, compression force, tablet hardness, disintegration time, and friability.

• Formulation - ingredients used in the tablet

• Compression force - pressure applied during tablet compression

• Tablet hardness - resistance to breaking

• Disintegration time - time taken for tablet to break down in the body

• Friability - tendency of tablet to break or crumble

LOD stands for Level of Detail. It refers to the amount of detail present in a model or visualization.

• LOD is commonly used in computer graphics to optimize performance by displaying less detail when objects are far away.

• It can also refer to the level of detail in data analysis, where different levels of granularity are used for different purposes.

• For example, in a 3D video game, LOD may be used to switch between high-d...read more

Cleaning validation is the process of ensuring that a cleaning procedure effectively removes residues from equipment used in the manufacturing process.

• Cleaning validation is essential in industries such as pharmaceuticals, food and beverage, and cosmetics.

• It involves establishing documented evidence that the cleaning process consistently removes residues to predetermined levels.

• Validation typically includes developing ...read more

Film coating is a process in which a thin layer of coating material is applied to a solid dosage form to improve appearance, taste, and stability.

• Film coating helps protect the drug from moisture, light, and air

• It can also mask the taste of the drug to improve patient compliance

• Examples of film-coated tablets include Advil and Tylenol

Stratified sample analysis helps ensure representative sampling, while content uniformity test ensures consistency of active ingredients in a sample.

• Stratified sample analysis involves dividing a population into subgroups based on certain characteristics before sampling.

• Content uniformity test is used to ensure that the amount of active ingredient in each dosage unit is consistent.

• Both techniques are important in quali...read more

CPP stands for Critical Process Parameters and CQA stands for Critical Quality Attributes of tablets.

• CPP are the key variables that must be controlled to ensure the tablet manufacturing process is successful.

• CQA are the characteristics that are critical to the quality of the tablet and must be monitored and controlled.

• Examples of CPP include mixing time, compression force, and drying temperature.

• Examples of CQA include...read more

Disintegration test is a test performed on tablets to determine the time it takes for a tablet to break down into smaller particles.

• Disintegration test helps to ensure that the tablet will disintegrate properly in the body for effective drug release.

• The criteria for disintegration test vary depending on the type of tablet and the intended use.

• Common criteria include the time it takes for the tablet to disintegrate into...read more

Parameters used in dry granulation and reasons for its use.

• Parameters include particle size, shape, and density of the powder material.

• Reasons for dry granulation include avoiding use of solvents, improving flow properties, and enhancing compressibility.

• Examples of dry granulation methods are slugging and roller compaction.

The wire diagram connects the PID controller to the Solid State Relay (SSR) and then to the heaters.

• Connect the output of the PID controller to the input of the SSR.

• Connect the output of the SSR to the heaters.

• Ensure proper grounding and insulation for safety.

• Use appropriate wire gauge based on the current requirements.

• Label all connections for easy troubleshooting.

• Consider using color-coded wires for easy identificati

An encapsulation machine schematic diagram shows the layout and components of the machine used to encapsulate products.

• The diagram typically includes components such as hopper, dosing disc, tamping pins, encapsulation chamber, and ejection system.

• The hopper is where the raw material is loaded, the dosing disc measures the amount of material, tamping pins compress the material, and the encapsulation chamber forms the ca...read more

Handling of divination involves interpreting signs or symbols to gain insight or guidance.

• Divination can involve various methods such as tarot cards, runes, pendulums, or scrying.

• Interpreting the results of divination requires intuition and understanding of symbolism.

• Divination is often used for spiritual guidance, decision-making, or gaining insight into the future.

Meghanalic gauge failure occurs when the meghanalic gauge fails to accurately measure pressure due to mechanical issues or calibration errors.

• Meghanalic gauge failure can be caused by mechanical damage to the gauge, such as a broken or bent needle.

• Calibration errors, such as incorrect zeroing or improper adjustment, can also lead to meghanalic gauge failure.

• Inaccurate readings from the gauge can result in incorrect pre...read more

Deviation process involves identifying, documenting, investigating, and resolving discrepancies from standard procedures.

• Identify the deviation from standard procedures or specifications

• Document the details of the deviation including date, time, location, and individuals involved

• Investigate the root cause of the deviation

• Implement corrective actions to prevent future deviations

• Review and approve the deviation documenta...read more