Zydus Lifesciences Quality Analyst Interview Questions and Answers

Troubleshooting of HPLC and GC involves identifying and resolving issues with the equipment to ensure accurate results.

• Perform regular maintenance checks on the equipment to prevent issues

• Calibrate the instruments regularly to maintain accuracy

• Check for leaks, blockages, or contamination in the system

• Verify the integrity of columns and detectors

• Review method parameters and conditions for any errors or inconsistencies

HPLC troubleshooting involves identifying and resolving issues with the instrument or the analysis process.

• Check for leaks in the system

• Verify the column is properly installed and conditioned

• Inspect the detector for any issues

• Ensure the mobile phase is prepared correctly

• Review the method parameters for accuracy

• Calibrate the instrument regularly

• Perform routine maintenance on the instrument

Types of HPLC columns include reverse phase, normal phase, ion exchange, size exclusion, and affinity. Types of GC columns include packed, capillary, and micro-packed columns.

• HPLC columns: reverse phase, normal phase, ion exchange, size exclusion, affinity

• GC columns: packed, capillary, micro-packed

Chromatography is a technique used to separate and analyze mixtures of chemicals based on their properties.

• Types of chromatography include gas chromatography, liquid chromatography, ion exchange chromatography, and affinity chromatography.

• Gas chromatography separates compounds based on their volatility and interactions with a stationary phase.

• Liquid chromatography separates compounds based on their affinity for the mobile and stationary phases.

• Ion exchange chromatography sepa...read more

IP USP weight variation refers to the acceptable range of weight variation in a pharmaceutical product.

• IP and USP are regulatory bodies that set standards for pharmaceutical products.

• Weight variation refers to the acceptable range of weight difference among individual units of a product.

• The acceptable range of weight variation depends on the type of product and its intended use.

• For example, tablets may have a weight variation limit of +/- 5% while capsules may have a limit of...read more

There are various types of tablets available in the market, including standard tablets, mini tablets, and convertible tablets.

• Standard tablets are the most common type and come in various sizes.

• Mini tablets are smaller in size and are more portable.

• Convertible tablets can be used as both a tablet and a laptop.

• Examples of popular tablets include the iPad, Samsung Galaxy Tab, and Microsoft Surface.