Pfizer Executive Research Trainee Interview Questions, Process, and Tips

HPLC is used for separating compounds in liquid phase, while GC is used for separating compounds in gas phase.

• HPLC stands for High Performance Liquid Chromatography, while GC stands for Gas Chromatography.

• HPLC is used for analyzing compounds that are heat-sensitive or non-volatile, while GC is used for volatile compounds.

• HPLC typically uses a liquid mobile phase and a solid stationary phase, while GC uses a gas mobile ...read more

Organic reaction mechanisms involve step-by-step processes by which organic molecules undergo chemical transformations.

• Nucleophilic substitution: involves the attack of a nucleophile on an electrophilic carbon atom, leading to the substitution of one group with another.

• Electrophilic addition: occurs when an electrophile reacts with a nucleophile to form a new bond, typically seen in alkene reactions.

• Elimination: involv...read more

NMR spectroscopy is suitable for organic reactions due to its ability to provide detailed structural information.

• NMR spectroscopy is commonly used to analyze organic compounds and reactions.

• It can provide information on the connectivity of atoms, functional groups, and stereochemistry.

• Examples of NMR techniques include 1H-NMR and 13C-NMR.

• NMR spectroscopy is non-destructive and can be used to monitor reactions in real-t

The IR value for carbonyl compounds is typically around 1700-1750 cm^-1, while other functional groups have characteristic IR values.

• Carbonyl compounds typically show a strong absorption band around 1700-1750 cm^-1 in the IR spectrum.

• Alcohols usually have a broad peak around 3200-3600 cm^-1 due to O-H stretching.

• Amines exhibit N-H stretching vibrations around 3300-3500 cm^-1.

• Alkenes show C=C stretching vibrations aroun...read more

Chromatography is a technique used to separate and analyze mixtures of chemicals.

• Types include gas chromatography, liquid chromatography, ion exchange chromatography, and affinity chromatography.

• Gas chromatography separates volatile compounds based on their boiling points.

• Liquid chromatography separates compounds based on their interactions with a stationary phase and a mobile phase.

• Ion exchange chromatography separate...read more