Intonation Research Laboratories Associate Scientist Interview Questions and Answers

Oxidative coupling reactions involve the formation of a covalent bond between two molecules through the removal of hydrogen atoms.

• Involves the formation of a new covalent bond between two molecules

• Typically involves the removal of hydrogen atoms

• Commonly used in organic synthesis to create complex molecules

• Examples include the Heck reaction and the Wacker process

Scientific knowledge encompasses facts, theories, and principles acquired through systematic study and experimentation.

• Scientific knowledge is based on empirical evidence and is subject to change as new evidence is discovered

• It is built upon the scientific method, which involves making observations, forming hypotheses, conducting experiments, and analyzing data

• Scientific knowledge is used to explain natural phenomena, ...read more

I want to join Aragen because of its reputation for cutting-edge research and collaborative work environment.

• Aragen is known for its innovative research projects

• I am impressed by the collaborative work culture at Aragen

• I believe Aragen offers great opportunities for professional growth and development

I will manage team productivity by setting clear goals, providing support and resources, fostering open communication, and monitoring progress.

• Set clear goals and expectations for each team member

• Provide necessary support and resources to help team members succeed

• Foster open communication and encourage collaboration among team members

• Monitor progress regularly and provide feedback to keep team on track

CIS and trance proton pattern in NMR refers to the orientation of protons in a molecule.

• CIS refers to the protons that are on the same side of a double bond or ring in a molecule

• Trans refers to the protons that are on opposite sides of a double bond or ring in a molecule

• The pattern of these protons can be observed in NMR spectroscopy and can provide information about the structure of the molecule

• For example, in a molec...read more

Oxidation of alcohol to acid is a chemical reaction that involves the loss of electrons from an alcohol molecule resulting in the formation of a carboxylic acid.

• The oxidation of primary alcohols results in the formation of aldehydes which are further oxidized to carboxylic acids.

• Secondary alcohols are oxidized to ketones which cannot be further oxidized.

• Tertiary alcohols cannot be oxidized to carboxylic acids.

• Common ox...read more

Cross coupling reaction involves the formation of a covalent bond between two different molecules or functional groups.

• It is a type of reaction used in organic chemistry to form carbon-carbon, carbon-nitrogen, or carbon-oxygen bonds.

• It involves the use of a catalyst, typically a transition metal, to facilitate the reaction.

• Examples include the Suzuki-Miyaura reaction, the Heck reaction, and the Stille reaction.

• Cross co...read more

HATU is used as a coupling reagent in acid amine coupling to form peptide bonds.

• HATU stands for 2-(1H-7-Azabenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate

• It is a highly efficient coupling reagent used in solid-phase peptide synthesis

• HATU activates carboxylic acids to form reactive intermediates that can react with amines to form peptide bonds

• It is preferred over other coupling reagents like DCC and DI...read more