200+ Sandeep Associates Interview Questions and Answers

Endotoxin is a type of toxin found in the cell wall of certain bacteria. USP chapters for water monitoring, media, and product are <1231>, <1116>, and <61>, respectively. The limits of cleanrooms are defined in USP chapter <797>. Four-hour monitoring in cleanrooms is done to ensure compliance with cleanliness standards.

• Endotoxin is a toxic substance present in the outer membrane of certain bacteria.

• USP chapter <1231> provides guidelines for water monitoring.

• USP chapter <1116>...read more

Calibration parameters of HPLC are used to ensure accurate and precise measurements of analytes.

• Calibration parameters include retention time, peak area, and peak height.

• Retention time is the time it takes for an analyte to pass through the column and be detected.

• Peak area and peak height are measures of the intensity of the analyte signal.

• Calibration curves are used to relate signal intensity to analyte concentration.

• Calibration parameters must be regularly checked and adjus...read more

Three mass and heat transfer operations at home and their correlation with manufacturing industry

• Boiling water for cooking (heat transfer) is similar to distillation in chemical industry

• Drying clothes (mass transfer) is similar to drying of solids in pharmaceutical industry

• Cooling drinks in refrigerator (heat transfer) is similar to cooling of chemicals in chemical industry

The estimated cost of 100ft x 100ft office with vitrified tiling, false ceiling, and furniture for 20 people.

• The cost of vitrified tiling varies depending on the quality and design chosen.

• False ceiling cost depends on the type of material used and the complexity of the design.

• Office furniture cost varies based on the type and quality of furniture selected.

• The estimated cost can range from $50,000 to $100,000 or more depending on the above factors.

10N HCl has a pH of 1 and 10N NaOH has a pH of 14 due to their high concentration of hydrogen and hydroxide ions respectively.

• 10N HCl is a strong acid with a high concentration of hydrogen ions, resulting in a low pH of 1.

• 10N NaOH is a strong base with a high concentration of hydroxide ions, resulting in a high pH of 14.

• The pH scale ranges from 0 to 14, with 7 being neutral.

• The concentration of hydrogen ions determines acidity, while the concentration of hydroxide ions determ...read more

The percentage of buffer used in mobile phase and the use of SLS in disso and its allowed percentage.

• The percentage of buffer used in the mobile phase depends on the specific experiment and the desired separation of compounds.

• Buffer is used in the mobile phase to maintain the pH and ionic strength, which can affect the separation and stability of analytes.

• The percentage of buffer can range from 5% to 50% or more, depending on the specific requirements.

• Sodium lauryl sulfate (S...read more

The reagent addition rate for exothermic reaction can be found by monitoring the temperature and adjusting the rate accordingly.

• Start with a small addition rate and gradually increase it while monitoring the temperature.

• Use a thermometer or temperature sensor to measure the temperature.

• Adjust the rate based on the temperature changes to maintain a steady reaction rate.

• Consider the reaction kinetics and the heat transfer properties of the system.

• Examples: Continuous stirred ta...read more

The calibration parameters of Balance monthly calibration include checking the accuracy and precision of the balance using standard weights.

• The balance is checked using standard weights of known mass.

• The accuracy and precision of the balance are evaluated.

• The calibration parameters may include the maximum allowable error and the number of calibration points.

• The calibration should be performed monthly to ensure accurate measurements.

• Documentation of the calibration should be k...read more

Deviations can be categorized based on their occurrence as frequent, occasional, or rare.

• Frequent deviations occur regularly and may require corrective action.

• Occasional deviations happen infrequently and may not require immediate action.

• Rare deviations are highly unusual and may require investigation to determine the cause.

• Examples of frequent deviations include equipment breakdowns or delays in production.

• Examples of occasional deviations include minor quality issues or del...read more

The region with the maximum mass flux is the hole on top of the hollow sphere.

• The hole on top allows the liquid methane to escape, resulting in a high mass flux.

• The remaining liquid methane in the sphere will have a lower mass flux.

• The mass flux is determined by the rate at which mass flows through a given area.

Head developed by a centrifugal pump does change when liquids of different specific gravity are used.

• Head developed by a centrifugal pump is directly proportional to the specific gravity of the liquid being pumped.

• When liquids of different specific gravity are used, the head developed by the pump will change.

• The pump curve should be consulted to determine the head developed by the pump for different liquids.

• The pump may need to be re-sized or adjusted to accommodate liquids o...read more

Epoxy flooring is a durable and long-lasting flooring solution made of epoxy resin and hardener.

• The surface is prepared by cleaning and etching

• The epoxy mixture is applied using a roller or squeegee

• A second coat may be applied after the first coat has cured

• The surface is left to cure for 24-72 hours

• Optional: a topcoat may be applied for added durability and shine

A PID temperature indicator controls temperature by adjusting heating/cooling based on feedback from sensors.

• PID stands for Proportional-Integral-Derivative, which are the three control modes used to adjust temperature.

• The indicator receives input from temperature sensors and compares it to the desired temperature setpoint.

• Based on the difference between the two, the PID controller adjusts the heating/cooling output to maintain the setpoint.

• The ramping function allows for gra...read more

MTSR, DSC, and TSC are metrics used in call centers to measure performance and efficiency.

• MTSR stands for Mean Time to Service Request and measures the average time it takes for a customer's service request to be resolved.

• DSC stands for Delayed Service Calls and measures the number of service calls that were not resolved within a certain timeframe.

• TSC stands for Total Service Calls and measures the total number of service calls received.

• MTSR and DSC are used to evaluate the e...read more

Dissolution test is performed to determine the rate at which a drug substance dissolves in a specified medium.

• Prepare the dissolution medium according to the specified requirements.

• Calibrate the dissolution apparatus by measuring the rotation speed, temperature, and other parameters.

• Place the drug substance in the dissolution vessel and start the test.

• Collect samples at specified time intervals and analyze the amount of drug dissolved.

• Compare the dissolution profile with the ...read more

Preparing buffers, differences between NP-HPLC and RP-HPLC, and uses of potentiometric titrations.

• Buffers are prepared by mixing a weak acid and its conjugate base or a weak base and its conjugate acid.

• NP-HPLC separates non-polar compounds while RP-HPLC separates polar compounds.

• Potentiometric titrations are used to determine the concentration of an unknown solution by measuring the potential difference between two electrodes.

• Potentiometric titrations are commonly used in the...read more

Materials can be charged using various methods such as direct contact, induction, or friction.

• Direct contact charging involves rubbing two materials together to transfer electrons.

• Induction charging involves bringing a charged object near the material to be charged, causing a transfer of electrons.

• Friction charging involves rubbing a material against a different material to transfer electrons.

• Materials can also be charged using static electricity or by exposure to a magnetic ...read more

There are several parameters for HPLC calibration.

• The parameters include accuracy, precision, linearity, range, limit of detection, and limit of quantification.

• Accuracy refers to how close the measured value is to the true value.

• Precision refers to the reproducibility of results.

• Linearity refers to the ability of the method to produce results that are proportional to the concentration of the analyte.

• Range refers to the concentration range over which the method is accurate and...read more

The degree of freedom of water at triple point is 0.

• Triple point is the temperature and pressure at which solid, liquid, and gas phases of a substance coexist in thermodynamic equilibrium.

• At triple point, the degree of freedom of a substance is zero because all three phases coexist in equilibrium.

• Water has a triple point at 273.16 K (0.01 °C) and a pressure of 611.73 Pa.

• At triple point, water can exist as ice, liquid water, and water vapor simultaneously.

Weight difference of two samples after ignition of ROI

• ROI stands for Residue on Ignition

• The weight difference is due to the loss of volatile substances during ignition

• The weight loss can be used to calculate the percentage of volatile substances in the sample

• This technique is commonly used in pharmaceutical and food industries

A clean room is a controlled environment with low levels of pollutants such as dust, airborne microbes, and chemical vapors.

• Clean rooms are used in industries such as pharmaceuticals, biotechnology, electronics, and aerospace.

• The requirements of a clean room area include controlled air flow, high-efficiency particulate air (HEPA) filters, and strict gowning procedures.

• Clean room classifications are based on the number of particles per cubic meter of air, with ISO Class 1 bein...read more

A Permit To Work system is a formal process to control high-risk activities in the workplace.

• It ensures that proper precautions are taken before starting any work that could potentially be hazardous.

• It involves obtaining a permit from a designated authority before commencing work.

• The permit outlines the specific tasks, hazards, safety measures, and duration of the work.

• Different types of work permits include hot work permits, confined space permits, electrical work permits, e...read more

The minimum value of n for which the sum of squares of the first n natural numbers is a multiple of 200 is 10.

• Calculate the sum of squares of the first n natural numbers

• Check if the sum is divisible by 200

• Increment n until the sum is divisible by 200

CAPA effectiveness can be checked by reviewing data and verifying if the corrective actions have been implemented and resolved the issue.

• Review data to ensure the issue has not reoccurred

• Verify if the corrective actions have been implemented

• Check if the corrective actions have resolved the issue

• Conduct follow-up audits to ensure sustained effectiveness

• Document all findings and actions taken for future reference

OOS stands for Out of Specification and OOT stands for Out of Trend. They are used to describe deviations from expected results.

• OOS refers to a result that falls outside the predetermined specifications or acceptance criteria.

• OOT refers to a result that shows a trend deviating from the expected or historical data.

• Both OOS and OOT can indicate potential quality issues and require investigation and corrective actions.

• Examples of OOS and OOT include a product failing a potency t...read more

Human resource management is the strategic approach to managing employees and their work within an organization.

• HR management involves recruiting, hiring, and training employees.

• It includes developing and implementing policies and procedures.

• HR managers handle employee relations, performance management, and compensation.

• They also ensure compliance with labor laws and promote a positive work culture.

• Examples of HR management tasks include conducting interviews, creating employ...read more

Calibration parameters of UV Vis Spectrophotometer

• Calibration parameters include wavelength accuracy, photometric accuracy, stray light, resolution, and noise.

• Wavelength accuracy is checked using holmium oxide or didymium glass filters.

• Photometric accuracy is checked using neutral density filters.

• Stray light is checked using potassium dichromate or sodium iodide solutions.

• Resolution is checked using holmium oxide or toluene solutions.

• Noise is checked using a blank solution.

• Ca...read more

Materials commonly used for making clean room areas include partition walls, coving, and specialized flooring.

• Partition walls in clean rooms are typically made of materials such as stainless steel, aluminum, or composite panels.

• Coving, which is the curved transition between the wall and floor, is often made of materials like PVC or stainless steel.

• Clean room flooring can be made of materials such as epoxy resin, vinyl, or rubber, which are easy to clean and maintain.

• Other mat...read more

Solvents should be dispensed in a well-ventilated area, away from heat sources and open flames.

• Wear appropriate personal protective equipment (PPE) such as gloves and safety glasses.

• Use a designated dispensing area with proper ventilation.

• Avoid smoking or using open flames near the dispensing area.

• Use a funnel to prevent spills and minimize contact with skin.

• Dispose of solvents properly according to local regulations.

• Examples of solvents include acetone, ethanol, and methanol...read more

Distillation is a process of separating components of a mixture based on their boiling points.

• The mixture is heated to vaporize the component with the lowest boiling point

• The vapor is then condensed and collected as a separate liquid

• This process is repeated for each component with a higher boiling point

• Example: Separating ethanol and water in alcoholic beverages

• Ethanol has a lower boiling point than water, so it vaporizes first and is collected as a separate liquid

To handle the equipment while working with goli game, one should follow proper safety protocols and guidelines.

• Ensure proper training on handling the equipment is provided

• Follow safety procedures and guidelines

• Regularly inspect and maintain the equipment

• Use appropriate personal protective equipment (PPE)

• Adhere to weight limits and load capacities

• Avoid rough handling or misuse of the equipment

• Report any equipment malfunctions or damages immediately

• Store the equipment properly ...read more

Validation and qualification are processes used in manufacturing to ensure that equipment, processes, and systems meet predefined standards and requirements.

• Validation is the process of establishing documented evidence that a system or process consistently produces results that meet predetermined specifications.

• Qualification is the process of demonstrating that an equipment or system is properly installed, operates correctly, and produces the expected results.

• CAPA stands for ...read more

The criteria/limit for impurity recovery depends on the specific research study and the desired purity level.

• The criteria for impurity recovery may include the maximum allowable impurity concentration or percentage.

• The limit for impurity recovery can be determined based on regulatory guidelines or industry standards.

• The desired purity level may vary depending on the application or intended use of the research findings.

• Impurity recovery criteria may also consider the potential...read more

XRD is a technique used to determine the crystal structure of a material. Crystalline and amorphous materials show different patterns.

• XRD stands for X-ray diffraction

• Crystalline materials have a regular, repeating pattern of atoms while amorphous materials lack this pattern

• XRD patterns of crystalline materials show sharp peaks while amorphous materials show broad peaks

• XRD can be used to identify unknown crystalline materials

• Examples of crystalline materials include diamond, q...read more

Nitrosamine impurities have limits set by regulatory bodies to ensure safety of pharmaceutical products.

• Nitrosamines are potentially carcinogenic impurities found in some pharmaceutical products.

• Regulatory bodies such as FDA and EMA have set limits for nitrosamine impurities in pharmaceutical products.

• The limits vary depending on the type of product and the route of administration.

• For example, the FDA has set a limit of 96 ng/day for nitrosamine impurities in ranitidine produ...read more

I'm sorry, I don't understand the question. Could you please rephrase it?

• The question seems unclear and may need to be rephrased

• It's possible that the interviewer made a mistake while asking the question

• Ask for clarification to ensure you understand what is being asked

Hold time varies for different stages of tablet production.

• Hold time refers to the duration for which a product is held at a particular stage before moving to the next stage.

• In tablet production, hold time varies for stages like granulation, compression, coating, and packaging.

• For example, the hold time for granulation can be around 24-48 hours, while for compression it can be around 2-3 hours.

• The hold time for coating can range from a few hours to a few days depending on the...read more

The highest selling product in my last company was a diabetes medication called Glucophage XR, used for managing blood sugar levels in patients with type 2 diabetes.

• Glucophage XR is a long-acting form of metformin, a commonly prescribed medication for diabetes management.

• It is indicated for the treatment of type 2 diabetes mellitus, particularly in overweight patients when diet and exercise alone are not enough to control blood sugar levels.

• The medication works by decreasing ...read more

OOS handling procedure is the process of managing and investigating out-of-specification results.

• OOS results should be reported immediately to the appropriate personnel.

• Investigation should be conducted to determine the root cause of the OOS result.

• Corrective and preventive actions should be implemented to prevent recurrence.

• Documentation of the investigation and actions taken should be maintained.

• Examples of OOS results include failed product specifications, abnormal test re...read more

As a Warehouse Executive, my job responsibilities include managing the receipt and dispensing procedures of raw and packaging materials, handling damaged containers, and ensuring proper calibration frequency and procedures.

• I am responsible for overseeing the receipt and dispensing procedures of raw and packaging materials.

• I handle damaged containers and ensure that they are properly disposed of.

• I am responsible for ensuring that calibration procedures are followed and that eq...read more

The salary package for a Quality Analyst varies depending on factors such as experience, location, and industry.

• Salary package for Quality Analysts can range from $50,000 to $100,000 per year.

• Factors that influence salary include years of experience, level of education, and certifications.

• Location plays a role in determining salary, with higher salaries typically found in metropolitan areas.

• Industry also impacts salary, with sectors like finance and technology often offering ...read more

The steps suggested in the Revenue recognition standard are identification, performance, and control.

• Identification of the contract with the customer

• Identification of the performance obligations in the contract

• Determination of the transaction price

• Allocation of the transaction price to the performance obligations

• Recognition of revenue when (or as) the entity satisfies a performance obligation

• Control of the goods or services transferred to the customer

The sink condition is decided based on various factors such as the purpose of the sink, the type of research being conducted, and the desired outcome.

• Consider the purpose of the sink - Is it for disposal, storage, or analysis of substances?

• Evaluate the type of research being conducted - Does it involve chemical reactions, biological samples, or physical measurements?

• Assess the desired outcome - Are you looking for preservation, degradation, or transformation of the substances...read more

Mass balance is a principle used in various scientific disciplines to account for the mass of substances in a system.

• Mass balance is based on the principle of conservation of mass, which states that mass cannot be created or destroyed, only transferred or transformed.

• It involves tracking the inputs, outputs, and accumulation of mass within a system.

• Mass balance equations are commonly used in environmental science, chemistry, and engineering.

• For example, in environmental scien...read more

Qbd approach involves designing and developing a formulation and process based on quality attributes and risk assessment.

• Qbd stands for Quality by Design

• It involves identifying critical quality attributes (CQAs) and critical process parameters (CPPs)

• Risk assessment is done to identify potential sources of variability and their impact on CQAs

• Formulation and process are then designed and developed to ensure consistent quality

• Example: Qbd approach for tablet formulation may invo...read more

ISO 8 particle count standard values

• ISO 8 cleanrooms must maintain a maximum particle count of 3,520,000 particles per cubic meter of air sized 0.5 microns and larger

• ISO 8 cleanrooms must maintain a maximum particle count of 29,300 particles per cubic meter of air sized 5 microns and larger

• Regular monitoring and testing is required to ensure compliance with ISO 8 standards

Yes, there are several Assistant Application Developer positions available in Hyderabad.

• Major IT companies like TCS, Infosys, and Wipro have openings for Assistant Application Developers in Hyderabad.

• Startups like Tech Mahindra and Cyient are also hiring for this role in Hyderabad.

• Candidates with experience in programming languages like Java, Python, and C# are preferred for this role.

• A Bachelor's degree in Computer Science or a related field is usually required for this posi...read more

The principles of the involved instruments/equipment refer to the fundamental concepts and theories behind their operation.

• Understanding the principles helps in troubleshooting and maintenance.

• Examples include the principles of electrical circuits for production equipment.

• Knowledge of the principles aids in optimizing production processes.

• Understanding the principles allows for effective utilization of the instruments/equipment.

• Examples include the principles of fluid dynamic...read more

Data errors in Pharma data science include missing data, incorrect data, duplicate data, and outliers.

• Missing data: When important data points are not recorded or are incomplete.

• Incorrect data: When data is entered or recorded incorrectly, leading to inaccurate analysis.

• Duplicate data: When the same data is recorded multiple times, skewing the analysis.

• Outliers: Data points that deviate significantly from the rest of the data, potentially affecting analysis results.

The current trends in deficiency include a focus on digital skills, sustainability, and diversity.

• Digital skills: With the increasing reliance on technology, there is a growing demand for professionals with expertise in areas like data analysis, artificial intelligence, and cybersecurity.

• Sustainability: Organizations are prioritizing sustainability practices to address environmental concerns. This has led to a need for professionals who can develop and implement sustainable s...read more

MOC stands for Material of Construction. Filters, vessels, and diaphragm valves can be made from various materials.

• MOC refers to the material used to construct filters, vessels, and diaphragm valves.

• Different materials have different properties and are suitable for different applications.

• Common materials used for filters include stainless steel, polypropylene, and ceramic.

• Vessels can be made from materials like carbon steel, fiberglass, or glass-lined steel.

• Diaphragm valves c...read more

Interlocks in a centrifuge are safety mechanisms that prevent the centrifuge from operating when certain conditions are not met.

• Interlock to prevent lid from opening while centrifuge is running

• Interlock to prevent centrifuge from operating if lid is not securely closed

• Interlock to prevent centrifuge from running if imbalance is detected

• Interlock to prevent centrifuge from running if temperature exceeds safe limits

As a Product Manager at Oracle, I led data analytics initiatives to improve product performance and customer experience.

• Developed and implemented data-driven strategies to optimize product features and pricing.

• Analyzed customer behavior and feedback to identify areas for improvement.

• Collaborated with cross-functional teams to design and launch new products based on market trends and customer needs.

• Used data visualization tools to present insights and recommendations to senior...read more

SAP codes are used in maintenance breakdowns for tracking and categorizing issues.

• SAP codes help in identifying specific types of breakdowns or issues in maintenance processes

• They streamline the reporting and tracking of maintenance problems

• Using SAP codes can improve efficiency and accuracy in maintenance management

• For example, a code like 'PM01' could represent a preventive maintenance issue

Batch start up precautions are necessary to ensure safe and efficient operation.

• Perform a thorough inspection of equipment and systems before starting up

• Ensure all necessary safety equipment is in place and functioning properly

• Follow established procedures for starting up the batch process

• Monitor the process closely during start up to identify and address any issues

• Train all personnel involved in the start up process on proper procedures and safety protocols

MOC stands for Material of Construction. Different MOCs for filters include stainless steel, polypropylene, and ceramic.

• MOC stands for Material of Construction

• Different MOCs for filters include stainless steel, polypropylene, and ceramic

Karl Fischer process is a method for measuring moisture content in a sample.

• Karl Fischer process is widely used in the pharmaceutical, chemical, and food industries.

• It involves the reaction between water and iodine in the presence of sulfur dioxide.

• The amount of iodine consumed in the reaction is proportional to the moisture content.

• The process can be performed using volumetric or coulometric titration.

• It is a sensitive and accurate method for moisture determination.

IPQA stands for In-Process Quality Assurance. It is a process of monitoring and verifying the quality of products during manufacturing.

• IPQA involves checking the quality of products at various stages of production.

• It helps in identifying and correcting any defects or deviations from the standard procedures.

• IPQA ensures that the final product meets the required quality standards.

• Examples of IPQA activities include visual inspection, measurement, and testing of products.

• IPQA is...read more

Yes, industry safety precautions are essential for QA QC Engineers to ensure the quality and safety of products.

• Knowledge of OSHA regulations and guidelines

• Understanding of hazard identification and risk assessment

• Training on proper use of personal protective equipment (PPE)

• Adherence to safety protocols and procedures in the workplace

• Regular inspections and audits to maintain safety standards

Water system refers to the network of pipes, pumps, and other equipment used to supply water to a community or building.

• Water is typically sourced from a natural source such as a river or lake, or from a well.

• The water is then treated to remove impurities and ensure it is safe for consumption.

• The treated water is then transported through a network of pipes to homes and businesses.

• Water pressure is maintained through the use of pumps and valves.

• Wastewater is collected and trea...read more

Elemental impurities guidance

• The guidance on elemental impurities is provided by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH)

• The specific guidance document is ICH Q3D: Guideline for Elemental Impurities

• This guidance provides recommendations on the control of elemental impurities in drug products and ingredients

• It outlines the permitted daily exposure limits for various elemental impurities and provides strategie...read more

The IR region range refers to the range of wavelengths in the infrared region of the electromagnetic spectrum.

• The IR region range typically spans from approximately 700 nanometers to 1 millimeter.

• It is divided into three main regions: near-infrared (NIR), mid-infrared (MIR), and far-infrared (FIR).

• Each region has different applications and characteristics. For example, NIR is commonly used in remote controls and optical communication, MIR is used in spectroscopy and thermal i...read more

Data integrity is crucial for ensuring accuracy and reliability of data. ALCOA and ALCOA Plus are guidelines for data integrity.

• ALCOA stands for Attributable, Legible, Contemporaneous, Original, and Accurate

• ALCOA Plus adds the principles of Complete, Consistent, Enduring, and Available

• These guidelines ensure that data is recorded accurately, completely, and consistently throughout its lifecycle

• Examples of ALCOA and ALCOA Plus principles in action include using electronic sign...read more

There are various types of procedures in Europe.

• Europe has different types of procedures in various fields such as legal, medical, administrative, etc.

• In the medical field, there are procedures like surgeries, diagnostic procedures, therapeutic procedures, etc.

• Legal procedures in Europe include court proceedings, arbitration, mediation, etc.

• Administrative procedures involve processes related to permits, licenses, registrations, etc.

There are multiple types of variations in Europe.

• Genetic variations: Differences in DNA sequences among individuals or populations.

• Cultural variations: Differences in customs, traditions, languages, and beliefs.

• Geographical variations: Differences in landscapes, climates, and natural resources.

• Economic variations: Differences in wealth, industries, and economic systems.

• Political variations: Differences in governance, laws, and political ideologies.

• Social variations: Differenc...read more

Current approaches on nitrosamine impurities

• Analytical techniques such as LC-MS and GC-MS are commonly used to detect and quantify nitrosamine impurities in pharmaceuticals

• Regulatory agencies have set limits on the acceptable levels of nitrosamine impurities in drugs

• Manufacturers are required to conduct risk assessments and implement control measures to prevent nitrosamine contamination

• Some common approaches to mitigate nitrosamine impurities include changing manufacturing pr...read more

The question is asking about the guidance for specification fixation.

• The guidance for specification fixation can vary depending on the industry and context.

• In software development, guidance can be found in industry standards like IEEE 830 or ISO/IEC/IEEE 29148.

• In project management, guidance can be found in methodologies like PRINCE2 or PMBOK.

• In manufacturing, guidance can be found in quality management systems like ISO 9001.

• In healthcare, guidance can be found in regulatory ...read more

HPLC and GC detectors differ in their principles of detection and types of analytes they can detect.

• HPLC detectors use UV-Vis, fluorescence, or electrochemical detection to analyze liquid samples.

• GC detectors use thermal conductivity, flame ionization, or mass spectrometry to analyze gas samples.

• HPLC is used for analyzing polar and non-volatile compounds, while GC is used for analyzing volatile compounds.

• HPLC detectors are more sensitive than GC detectors.

• Both detectors have ...read more

Downstream processing involves the purification and separation of products in biotechnology and pharmaceutical industries.

• Downstream processing is a crucial step in the production of biopharmaceuticals.

• It involves the purification and separation of the desired product from the fermentation broth or cell culture.

• Techniques used in downstream processing include filtration, chromatography, centrifugation, and precipitation.

• The goal is to remove impurities and obtain a highly pur...read more

The company vessel used varies depending on the company and its operations.

• Different companies use different vessels depending on their needs and operations.

• Some companies may use cargo ships for transporting goods, while others may use research vessels for scientific expeditions.

• Examples of company vessels include Maersk Line's Triple E class container ships and Ocean Infinity's Seabed Constructor.

• The type of vessel used may also depend on the industry, such as oil and gas c...read more

The interview question covers major equipment breakdowns, equipment interlocking, engineering documentation, implementations, and cost-saving activities.

• Major equipment breakdowns require identifying the root cause, finding a solution, and implementing a Corrective and Preventive Action (CAPA).

• Equipment interlocking ensures that certain equipment functions only when specific conditions are met.

• Engineering documentation includes technical specifications, drawings, and manuals ...read more

Methycobalamin is used for the treatment of vitamin B12 deficiency and related conditions.

• Methycobalamin is a form of vitamin B12 that is used to treat vitamin B12 deficiency.

• It is commonly prescribed for conditions such as pernicious anemia, neuropathy, and megaloblastic anemia.

• Methycobalamin helps in the production of red blood cells and nerve cells, and it plays a crucial role in maintaining the health of the nervous system.

• It is available in various forms such as tablets,...read more

Dr. Reddy's lab is located in Hyderabad, India.

• Dr. Reddy's Laboratories Limited is located in Hyderabad.

• It is situated in the Kukatpally area of the city.

• The lab is easily accessible by road and public transport.

• It is a leading pharmaceutical company in India.

I am expecting a competitive salary package with benefits such as health insurance, paid time off, and opportunities for professional development.

• Competitive salary

• Health insurance

• Paid time off

• Professional development opportunities

I am expecting a competitive salary package with benefits and opportunities for growth.

• Competitive salary

• Benefits package (health insurance, retirement plan, etc.)

• Opportunities for growth and advancement

• Additional perks (bonus, flexible work hours, etc.)

Antibiotics are not typically used to stop bleeding. Hemostatic agents like tranexamic acid or desmopressin are more commonly used.

• Antibiotics are not used to stop bleeding, as they are used to treat bacterial infections.

• Hemostatic agents like tranexamic acid or desmopressin are commonly used to stop bleeding.

• In some cases, blood clotting factors or platelet transfusions may be used to control bleeding.

Acids are chemical compounds that release hydrogen ions when dissolved in water, with uses in various industries such as manufacturing, cleaning, and food preservation.

• Acids have a pH level below 7, indicating their acidic nature

• Common acids include sulfuric acid, hydrochloric acid, and citric acid

• Uses of acids include metal cleaning, food preservation, and pH regulation in various processes

UV range refers to the range of ultraviolet radiation wavelengths.

• UV range is typically divided into three categories: UVA (320-400 nm), UVB (280-320 nm), and UVC (100-280 nm).

• UVA is responsible for skin aging and wrinkling, while UVB causes sunburn and skin cancer.

• UVC is absorbed by the ozone layer and does not reach the Earth's surface.

• UV radiation can also be used for disinfection and sterilization purposes.

• UV range is important to consider when using sunscreen or other pr...read more

Phenol is a white crystalline solid with a distinct odor and is soluble in water.

• Phenol is highly reactive and can cause severe burns upon contact with skin.

• It is used as a disinfectant and in the production of plastics, resins, and pharmaceuticals.

• Phenol is toxic and can cause respiratory and neurological problems if inhaled.

• It can also cause liver and kidney damage if ingested.

• Phenol is a weak acid and can react with bases to form salts called phenolates.

There are different types of integration such as vertical, horizontal, forward, backward, and bi-directional.

• Vertical integration involves the integration of different levels of the same supply chain.

• Horizontal integration involves the integration of different companies at the same level of the supply chain.

• Forward integration involves the integration of a company with its distributors or retailers.

• Backward integration involves the integration of a company with its suppliers....read more

Dew Point is the temperature at which air becomes saturated and condensation occurs. Coating is a process of applying a layer of material onto a surface.

• Dew Point is the temperature at which air can no longer hold all of its water vapor, leading to condensation.

• It is determined by the amount of moisture in the air and the air temperature.

• When the air temperature drops below the dew point, water vapor in the air condenses into liquid water.

• Coating is a process of applying a la...read more

Isolators are used to prevent the flow of electricity between two points.

• Isolators are used to disconnect a circuit from its power source for maintenance or repair.

• They are also used to provide a physical barrier to prevent accidental contact with live parts.

• Isolators are commonly used in electrical distribution systems and industrial settings.

• Examples of isolators include circuit breakers, disconnect switches, and fuse holders.

The filing of a CEP in Europe depends on various factors such as the type of product, regulatory requirements, and the timeline of the application process.

• The filing of a CEP (Certificate of European Pharmacopoeia) in Europe is typically done when seeking approval for a pharmaceutical product.

• The exact timing of the filing depends on the stage of development of the product and the regulatory strategy of the company.

• CEP filings are usually made after the completion of preclini...read more

A summary report that documents the results of a validation process.

• Provides an overview of the validation process and its outcomes

• Includes a description of the system or process being validated

• Lists the validation activities performed and their results

• Summarizes any deviations or issues encountered during validation

• Concludes with a statement on the overall validation status

• May include recommendations for future improvements

• Example: A validation summary report for a pharmaceu...read more

I have worked on 3 types of PLCs - Siemens, Allen Bradley and Mitsubishi.

• Siemens

• Allen Bradley

• Mitsubishi

I can solve Rubik's cube in under 2 minutes.

• I have been practicing solving Rubik's cube for a while now.

• I use a specific method to solve the cube efficiently.

• My average solving time is around 1 minute and 30 seconds.

• I can solve the cube blindfolded as well.

Troubleshooting of HPLC system involves identifying and resolving issues to ensure accurate and reliable results.

• Check for leaks in the system

• Inspect and clean the column

• Verify the mobile phase composition

• Calibrate and check the detectors

• Troubleshoot software or connectivity issues

• Perform system suitability tests

• Consult instrument manuals or contact technical support if needed

The current company rules and regulations are outlined in the employee handbook.

• The employee handbook covers topics such as attendance, dress code, and workplace behavior.

• Employees are expected to follow all rules and regulations outlined in the handbook.

• Violations of company policies may result in disciplinary action, up to and including termination.

• The handbook is regularly updated to reflect changes in company policies and regulations.

HPLC and GC detectors differ in their principles of detection and types of analytes they can detect.

• HPLC detectors use UV-Vis, fluorescence, or electrochemical detection to analyze liquid samples, while GC detectors use thermal conductivity, flame ionization, or mass spectrometry to analyze gas samples.

• HPLC detectors are suitable for analyzing polar and non-volatile compounds, while GC detectors are better for analyzing volatile and semi-volatile compounds.

• HPLC detectors are ...read more

ESI and APCI are ionization techniques used in mass spectrometry. Method development for impurities involves identification, quantification, and validation.

• ESI (Electrospray Ionization) and APCI (Atmospheric Pressure Chemical Ionization) are ionization techniques used in mass spectrometry.

• ESI is suitable for polar and ionic compounds, while APCI is suitable for nonpolar and less polar compounds.

• ESI involves the formation of ions by the interaction of a sample with charged dro...read more

I will increase sales in my territory by implementing targeted marketing strategies and building strong relationships with key customers.

• Conduct market research to identify customer needs and preferences

• Develop targeted marketing campaigns to reach specific customer segments

• Build strong relationships with key customers through regular communication and personalized service

• Offer promotions and discounts to incentivize purchases

• Provide excellent customer service to ensure custo...read more

Hvac validation involves ensuring that the heating, ventilation, and air conditioning systems meet required standards and specifications.

• Hvac validation involves testing and verifying that the system operates correctly and efficiently.

• Hvac differential process monitoring involves monitoring temperature, pressure, and airflow differentials to ensure proper functioning.

• Designing of Hvac systems involves creating layouts, selecting equipment, and determining optimal placement fo...read more

Tiering for MBA campus hires should be based on performance, potential, and fit with the organization.

• Consider performance in academic achievements, internships, and extracurricular activities.

• Assess potential for growth and leadership based on communication skills, problem-solving abilities, and adaptability.

• Evaluate fit with the organization's culture, values, and long-term goals.

• Create tiers based on a combination of these factors to ensure a diverse and well-rounded group...read more

Yes, the doctor list can be reduced based on certain criteria.

• Identify doctors who have retired or relocated.

• Remove doctors who are no longer practicing in the relevant field.

• Exclude doctors who have requested to be removed from the list.

• Consider removing doctors who have consistently shown low prescription rates.

• Review doctors who have received negative feedback or complaints.

• Evaluate doctors who have not shown interest in the products or services offered.