Biocon Limited QC Chemist Interview Questions and Answers

The challenge test of a machine is a test to determine its capabilities and limitations.

• The challenge test should be designed to push the machine to its limits.

• It should be conducted in a controlled environment to ensure safety.

• Examples of challenge tests include stress tests, endurance tests, and performance tests.

• The results of the challenge test can be used to improve the machine's design and performance.

FFS machine stands for Form-Fill-Seal machine, which is a packaging machine used to form, fill, and seal products in various industries.

• FFS machine is commonly used in industries such as food and beverage, pharmaceuticals, and cosmetics.

• It is an automated machine that can produce packaging materials on-site.

• The machine forms a package from a flat roll of film, fills it with the product, and then seals it.

• FFS machines c...read more

Kaizen is a Japanese term for continuous improvement. It involves making small, incremental changes to improve processes and systems.

• Kaizen is a philosophy that focuses on continuous improvement in all aspects of an organization.

• It involves identifying areas for improvement, making small changes, and then evaluating the results.

• Kaizen can be applied to any process or system, from manufacturing to healthcare.

• Examples of...read more

Transformers are electrical devices that transfer energy between two or more circuits through electromagnetic induction.

• Transformers are used to increase or decrease voltage levels in electrical circuits

• They consist of two coils of wire wrapped around a magnetic core

• The primary coil is connected to the input voltage and the secondary coil to the output load

• Step-up transformers increase voltage while step-down transform...read more

Water content mechanism can be found through various methods and is important for various reasons.

• Water content can be measured through techniques such as gravimetric analysis, Karl Fischer titration, and moisture analyzers.

• Water content is important in industries such as food, pharmaceuticals, and cosmetics to ensure product quality and stability.

• Water content is also important in environmental studies to understand t...read more

Developing HPLC methods involves selecting appropriate columns and optimizing parameters.

• Choose a suitable column based on the analyte's properties and the separation goal.

• Optimize parameters such as mobile phase composition, flow rate, and temperature.

• Validate the method by assessing its selectivity, sensitivity, accuracy, and precision.

• Common column types include C18, C8, and phenyl.

• Other factors to consider include ...read more

Carbon loading in column refers to the amount of carbon used in the stationary phase of a chromatography column. Endcapping is a process to block the remaining silanol groups on the surface of the stationary phase.

• Carbon loading is typically expressed as a percentage of the total weight of the stationary phase.

• Higher carbon loading can improve the selectivity and retention of certain analytes.

• Endcapping is important to...read more

Acceptance limit of validations refers to the maximum allowable deviation from a standard or specification.

• Acceptance limit is determined by regulatory agencies or industry standards.

• It is used to ensure that products or processes meet quality standards.

• For example, the acceptance limit for a drug potency test may be +/- 5% of the labeled potency.

• Acceptance limits can vary depending on the type of validation being perf...read more