10+ Ipqa Chemist Interview Questions and Answers

Line clearance, contamination, cross contamination, autoclave principle and temperature, calibration and validation, data integrity, and clean rooms are important concepts in pharmaceutical manufacturing.

• Line clearance is the process of ensuring that equipment and work areas are free of any materials from previous operations.

• Contamination is the presence of any harmful substance in a product or environment.

• Cross contamination is the transfer of harmful substances from one pro...read more

Valency of carbon differs in organic and inorganic compounds due to the presence of functional groups.

• Organic compounds contain carbon-carbon and carbon-hydrogen bonds with a valency of 4.

• Inorganic compounds may have different valencies for carbon depending on the functional group present.

• For example, carbon in carbon dioxide has a valency of 4, while in methane it has a valency of 2.

• Valency is important in determining the reactivity and properties of compounds.

In process control is a system of checks and measures to ensure quality and consistency during the manufacturing process.

• In process control involves monitoring and adjusting variables such as temperature, pressure, and pH levels to maintain quality standards.

• It includes sampling and testing of raw materials, intermediates, and finished products to ensure they meet specifications.

• Examples of in process control techniques include statistical process control, process capability ...read more

Weight variation criteria as per IP & USP

• Weight variation criteria for tablets as per IP is not more than 7.5% of the average weight

• Weight variation criteria for capsules as per USP is not more than 10% of the average weight

• Weight variation criteria may vary for different dosage forms and pharmacopoeias

Quality assurance is a process that ensures products or services meet specified requirements and standards.

• Quality assurance involves establishing processes to prevent defects and errors in products or services

• It focuses on continuous improvement and monitoring of processes to ensure consistency and quality

• Examples include conducting audits, inspections, and testing to verify compliance with standards

Regulatory bodies are organizations that enforce laws and regulations to ensure compliance and safety in various industries.

• Regulatory bodies set standards and guidelines for companies to follow

• They monitor and inspect businesses to ensure compliance with regulations

• Examples include FDA in the pharmaceutical industry and EPA in the environmental sector

Patents play a crucial role in protecting the intellectual property of biopharmaceutical companies.

• Patents provide legal protection for the unique processes, methods, and products developed by biopharmaceutical companies.

• They allow companies to recoup their investment in research and development by preventing competitors from copying their innovations.

• Patents also encourage innovation by providing an incentive for companies to invest in research and development.

• Without patent...read more

Line clearance in compression area is essential to prevent cross-contamination and ensure product quality.

• Line clearance involves removing any previous product residues, cleaning equipment, and verifying cleanliness before starting a new batch.

• It helps prevent mix-ups, contamination, and errors during production.

• Examples of line clearance activities include visual inspection, swab testing, and documentation of cleaning procedures.

• Proper training and adherence to standard oper...read more

Average weight is crucial in pharmaceutical formulations, defined by IP, BP, and USP standards.

• Average weight is the mean weight of a specific quantity of a substance.

• IP (Indian Pharmacopoeia) defines average weight for various drugs and formulations.

• BP (British Pharmacopoeia) provides guidelines on average weight for medicinal products.

• USP (United States Pharmacopeia) specifies average weight in relation to dosage forms.

• Example: For tablets, average weight ensures uniformity...read more

Good Manufacturing Practices (GMP) are guidelines and regulations set by regulatory agencies to ensure the quality and safety of pharmaceutical products.

• GMP ensures that pharmaceutical products are consistently produced and controlled according to quality standards.

• It includes guidelines for manufacturing processes, facilities, equipment, personnel, documentation, and more.

• Adherence to GMP helps prevent contamination, mix-ups, and errors in production.

• Examples of GMP requirem...read more

Titration is a technique used in chemistry to determine the concentration of a substance in a solution.

• Acid-base titration: involves the reaction between an acid and a base to determine the concentration of either

• Redox titration: involves the transfer of electrons between reactants to determine the concentration of a substance

• Complexometric titration: involves the formation of a complex between a metal ion and a ligand to determine the concentration of the metal ion

• Precipitat...read more