Biocon Limited Chemist Interview Questions and Answers

Water content mechanism can be found through various methods and is important for various reasons.

• Water content can be measured through techniques such as gravimetric analysis, Karl Fischer titration, and moisture analyzers.

• Water content is important in industries such as food, pharmaceuticals, and cosmetics to ensure product quality and stability.

• Water content is also important in environmental studies to understand t...read more

Developing HPLC methods involves selecting appropriate columns and optimizing parameters.

• Choose a suitable column based on the analyte's properties and the separation goal.

• Optimize parameters such as mobile phase composition, flow rate, and temperature.

• Validate the method by assessing its selectivity, sensitivity, accuracy, and precision.

• Common column types include C18, C8, and phenyl.

• Other factors to consider include ...read more

Carbon loading in column refers to the amount of carbon used in the stationary phase of a chromatography column. Endcapping is a process to block the remaining silanol groups on the surface of the stationary phase.

• Carbon loading is typically expressed as a percentage of the total weight of the stationary phase.

• Higher carbon loading can improve the selectivity and retention of certain analytes.

• Endcapping is important to...read more

Data integrity refers to the accuracy, consistency, and reliability of data throughout its lifecycle.

• Data integrity ensures that data remains unchanged and reliable over time.

• It involves maintaining the accuracy and consistency of data during storage, processing, and transmission.

• Data integrity can be achieved through various measures such as checksums, encryption, and access controls.

• Examples of data integrity issues ...read more

CAPA stands for Corrective and Preventive Action.

• CAPA is a systematic approach to identify, investigate, and resolve quality issues.

• It involves analyzing the root cause of the problem and implementing corrective actions to prevent recurrence.

• CAPA is commonly used in industries such as manufacturing, pharmaceuticals, and healthcare.

• Examples of CAPA tools and techniques include 5 Whys, Fishbone Diagrams, and Pareto Analy

Calibration is required to ensure accuracy and consistency of measurements and equipment.

• Calibration helps to maintain the quality of products and services.

• It ensures that measurements are accurate and consistent, reducing errors and improving efficiency.

• Calibration is necessary for compliance with industry standards and regulations.

• Examples of equipment that require calibration include scales, thermometers, and medica...read more

I would clarify the reason behind the request and discuss any potential impact on the analysis.

• Ask for clarification on the reason for skipping the step

• Discuss any potential impact on the analysis

• Provide alternative solutions if possible

Normality refers to the state of being normal or conforming to a standard or average.

• Normality is a concept used in various fields to define what is considered typical or expected.

• It is often used in statistics to describe the distribution of data points around a mean.

• In psychology, normality refers to behavior that is within the range of what is considered socially acceptable.

• Normality can also be subjective, varying ...read more

Molarity is a measure of the concentration of a solution expressed as the number of moles of solute per liter of solution.

• Molarity is calculated by dividing the number of moles of solute by the volume of the solution in liters.

• It is denoted by the symbol 'M'.

• Molarity is commonly used in chemistry to express the concentration of a solution.

• For example, a 1 M solution of sodium chloride contains 1 mole of sodium chloride

Molarity is the concentration of a solution in terms of the number of moles of solute per liter of solution, while molality is the concentration of a solution in terms of the number of moles of solute per kilogram of solvent.

• Molarity is denoted by M, while molality is denoted by m.

• Molarity is affected by temperature changes, while molality is not.

• Molarity is used in chemical reactions, while molality is used in colliga...read more

HPLC stands for High Performance Liquid Chromatography. It is a principle used in analytical chemistry to separate, identify, and quantify components in a mixture.

• HPLC uses a liquid mobile phase and a solid stationary phase to separate components based on their interactions with the stationary phase.

• The principle is based on the differential partitioning of components between the mobile and stationary phases.

• Components...read more

The principle of UV-spectrophotometer is based on the absorption of ultraviolet (UV) light by molecules.

• UV-spectrophotometer measures the absorbance of UV light by a sample.

• The absorbance is directly proportional to the concentration of the absorbing species in the sample.

• The principle is used in various applications such as quantitative analysis, purity determination, and kinetics studies.

• UV-spectrophotometer operates...read more

Quality assurance focuses on preventing defects while quality control focuses on identifying and correcting defects.

• Quality assurance is a proactive process that involves planning, designing, and implementing processes to prevent defects from occurring.

• Quality control is a reactive process that involves identifying defects and taking corrective action to eliminate them.

• Quality assurance is focused on the entire process...read more