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Zydus Lifesciences
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I applied via Company Website and was interviewed in May 2021. There were 3 interview rounds.
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posted on 23 Dec 2024
I applied via Walk-in and was interviewed in Nov 2024. There were 2 interview rounds.
LOQ stands for Limit of Quantitation as per ICH guidelines. It is the lowest concentration of an analyte that can be reliably measured.
LOQ is determined by analyzing a series of samples with known concentrations of the analyte and calculating the standard deviation and slope of the calibration curve.
The LOQ is typically defined as the concentration at which the signal-to-noise ratio is at least 10:1.
It is important to ...
Specificity in assay method refers to the ability of the method to accurately measure only the target analyte without interference from other substances.
Specificity is determined by testing the method with known standards and samples containing the target analyte as well as potential interfering substances.
Cross-reactivity with similar compounds should be evaluated to ensure the method is specific to the target analyte...
Mechanical calibration of Dissolution Apparatus involves ensuring the apparatus is functioning accurately and consistently.
Calibration involves checking the alignment of the shaft, speed of rotation, temperature control, and vessel centering.
Regular calibration is necessary to ensure accurate and reliable dissolution testing results.
Examples of calibration methods include using standard weights for balance calibration ...
Solubility studies are conducted to determine the ability of a substance to dissolve in a particular solvent.
Solubility studies involve testing the solubility of a substance in different solvents.
Various methods such as shake flask method, equilibrium solubility method, and kinetic solubility method can be used.
Factors affecting solubility include temperature, pH, and particle size.
Analytical techniques like UV-Vis spe...
posted on 29 Sep 2022
I applied via Approached by Company and was interviewed in Sep 2022. There were 2 interview rounds.
The interview question asks about dissolution and method development, formulation handling, force degradation, lipid content analysis, and the use of membrane filters in methods.
Dissolution refers to the process of a solid substance dissolving in a liquid medium.
Method development involves creating and optimizing analytical methods for various purposes.
Formulations handled can include tablets, capsules, suspensions, or...
Method development critical for accurate lipid analysis. Different lipids require different methods.
Method development is crucial for accurate lipid analysis
Different lipids require different methods for analysis
Factors like polarity, solubility, and structure affect method development
Examples of lipids include triglycerides, phospholipids, and cholesterol esters
posted on 25 Apr 2024
I applied via Approached by Company and was interviewed before Apr 2023. There were 3 interview rounds.
posted on 11 Jul 2021
I applied via Referral and was interviewed before Jul 2020. There were 3 interview rounds.
Mechanism of reactions refers to the step-by-step process by which a chemical reaction occurs.
Mechanism of reactions involves the breaking and forming of chemical bonds.
It includes the identification of intermediates and transition states.
Understanding the mechanism of a reaction can help predict the outcome of the reaction and optimize reaction conditions.
Examples include SN1 and SN2 reactions in organic chemistry and
posted on 26 Oct 2023
I applied via Naukri.com and was interviewed in Sep 2023. There were 2 interview rounds.
The percentage of buffer used in mobile phase and the use of SLS in disso and its allowed percentage.
The percentage of buffer used in the mobile phase depends on the specific experiment and the desired separation of compounds.
Buffer is used in the mobile phase to maintain the pH and ionic strength, which can affect the separation and stability of analytes.
The percentage of buffer can range from 5% to 50% or more, depen...
The sink condition is decided based on various factors such as the purpose of the sink, the type of research being conducted, and the desired outcome.
Consider the purpose of the sink - Is it for disposal, storage, or analysis of substances?
Evaluate the type of research being conducted - Does it involve chemical reactions, biological samples, or physical measurements?
Assess the desired outcome - Are you looking for pres...
The criteria/limit for impurity recovery depends on the specific research study and the desired purity level.
The criteria for impurity recovery may include the maximum allowable impurity concentration or percentage.
The limit for impurity recovery can be determined based on regulatory guidelines or industry standards.
The desired purity level may vary depending on the application or intended use of the research findings.
...
Mass balance is a principle used in various scientific disciplines to account for the mass of substances in a system.
Mass balance is based on the principle of conservation of mass, which states that mass cannot be created or destroyed, only transferred or transformed.
It involves tracking the inputs, outputs, and accumulation of mass within a system.
Mass balance equations are commonly used in environmental science, chem...
RF values are important in chromatography to identify and separate compounds.
RF value is the ratio of the distance traveled by a compound to the distance traveled by the solvent front in chromatography.
It helps in identifying and separating compounds based on their polarity and solubility.
RF values can be used to compare compounds and determine their purity.
For example, in thin-layer chromatography, RF values are used ...
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