Vital Healthcare Quality Assurance Chemist Interview Questions and Answers

Potassium iodide (KI) is commonly used in Karl Fischer (KF) titration.

• Potassium iodide (KI) is added to the Karl Fischer reagent to enhance the solubility of water.

• KI reacts with water to form iodine, which is then titrated with the Karl Fischer reagent.

• The reaction between KI and water in KF titration is as follows: KI + SO2 + H2O → KHSO4 + I2

• The iodine formed is then quantitatively determined by titration with the Ka...read more

HPLC is a technique used to separate, identify, and quantify components in a mixture.

• HPLC stands for High Performance Liquid Chromatography.

• It is commonly used in pharmaceuticals, food and beverage, and environmental testing.

• HPLC can separate and quantify complex mixtures of compounds.

• It can be used to detect impurities in drugs and determine their concentration.

• HPLC can also be used to analyze the composition of food ...read more

FTIR is a powerful analytical technique used for identifying and quantifying chemical compounds.

• Advantages: non-destructive, rapid, requires minimal sample preparation, can analyze a wide range of compounds, can be used for qualitative and quantitative analysis

• Disadvantages: expensive equipment, requires trained personnel, may require calibration, may not be suitable for analyzing certain compounds

• Example: FTIR can be ...read more

pH is a measure of the acidity or alkalinity of a solution.

• pH stands for 'potential of hydrogen'.

• It is a logarithmic scale ranging from 0 to 14.

• A pH of 7 is considered neutral, below 7 is acidic, and above 7 is alkaline.

• pH is determined by the concentration of hydrogen ions in a solution.

• Examples: Lemon juice has a pH of around 2, while baking soda has a pH of around 9.

PH represents the concentration of hydrogen ions in a sample.

• PH is measured on a scale of 0-14, with 7 being neutral.

• A lower PH indicates higher acidity, while a higher PH indicates higher alkalinity.

• PH can be measured using a PH meter or through chemical indicators.

• The PH of a sample can affect its chemical properties and reactions.

LOD stands for Limit of Detection. It is the lowest concentration of a substance that can be reliably detected.

• LOD is used to determine the sensitivity of an analytical method.

• It is usually expressed as a concentration or mass.

• Water is a chemical compound composed of hydrogen and oxygen, while LOD is a term used in analytical chemistry.

• LOD is important in environmental testing to determine the presence of contaminants ...read more