10+ o3Capital Interview Questions and Answers

Bulk density is the mass of a powder per unit volume, while tapped density is the mass of a powder per unit volume after tapping. Compressibility index is a measure of the powder's ability to be compressed.

• Bulk density is determined by measuring the mass of a known volume of powder.

• Tapped density is determined by measuring the mass of a known volume of powder after tapping it a specified number of times.

• Compressibility index is calculated by subtracting the tapped density fro...read more

Deviation and Change control are processes used in pharmaceutical manufacturing to ensure quality and compliance with 21 CFR regulations.

• Deviation control is the process of documenting and investigating any deviation from established procedures or specifications.

• Change control is the process of managing changes to established procedures or specifications to ensure they are properly evaluated and approved before implementation.

• 21 CFR refers to the regulations set forth by the ...read more

Particle size distribution refers to the range of particle sizes in a sample.

• It is commonly measured using techniques such as sieving, sedimentation, and laser diffraction.

• Particle size distribution can affect the properties and behavior of a material, such as its flowability and reactivity.

• Examples of industries that may be concerned with particle size distribution include pharmaceuticals, food processing, and mining.

• Particle size distribution can also impact the performance...read more

The end point of RMG is granules and FBD is dried granules.

• RMG (Roller Compaction) is used to convert powder into granules.

• The end point of RMG is the formation of granules.

• FBD (Fluid Bed Dryer) is used to dry wet granules.

• The end point of FBD is the production of dried granules.

RMG, FBD, and sifter are equipment used in pharmaceutical manufacturing.

• RMG (Rapid Mixer Granulator) is used for wet granulation process.

• FBD (Fluid Bed Dryer) is used for drying and granulation of powders.

• Sifter is used for separating and grading of powders.

• All three equipment are commonly used in pharmaceutical manufacturing.

• RMG and FBD are often used together in a continuous manufacturing process.

Regulatory bodies are organizations that oversee and regulate industries and activities to ensure compliance with laws and standards.

• Regulatory bodies vary by country and industry

• Examples include the FDA in the US, EMA in Europe, and TGA in Australia for medical products

• Other regulatory bodies include the SEC for financial markets and the EPA for environmental regulations

• Regulatory bodies enforce laws and regulations through inspections, audits, and penalties for non-complian...read more

Cyber security in pharmaceutical industry provides protection against data breaches, intellectual property theft, and regulatory non-compliance.

• Prevents unauthorized access to sensitive data and confidential information

• Protects against cyber attacks that can disrupt operations and compromise patient safety

• Ensures compliance with regulations such as HIPAA and GDPR

• Safeguards intellectual property and trade secrets from theft or misuse

• Reduces the risk of reputational damage and ...read more

Marketing strategy for OTT platform involves targeting the right audience, creating engaging content, and leveraging social media.

• Identify target audience and their preferences

• Create original and engaging content

• Leverage social media platforms for promotion

• Offer free trials and discounts to attract new users

• Collaborate with influencers and content creators

• Invest in SEO and SEM to increase visibility

• Personalize recommendations and user experience

• Analyze data to optimize market...read more

The USP specifies the apparatus to be used in dissolution testing.

• USP specifies different types of apparatus for dissolution testing such as Apparatus 1 (basket), Apparatus 2 (paddle), Apparatus 3 (reciprocating cylinder), etc.

• The choice of apparatus depends on the specific drug being tested and its characteristics.

• Each apparatus has its own set of specifications and operating conditions outlined in the USP.

• It is important for Quality Control Officers to be familiar with the ...read more

HPLC, GC, UV, and IR are all analytical techniques used in chemistry and related fields.

• HPLC stands for High Performance Liquid Chromatography and is used to separate, identify, and quantify components in a mixture.

• GC stands for Gas Chromatography and is used to separate and analyze volatile compounds.

• UV stands for Ultraviolet-Visible Spectroscopy and is used to identify and quantify compounds based on their absorption of UV or visible light.

• IR stands for Infrared Spectroscop...read more

Vial types and sizes vary depending on their purpose and industry.

• Vials are small containers typically made of glass or plastic.

• They are used for storing and dispensing liquids, powders, or small solid objects.

• Common vial sizes include 2 mL, 5 mL, 10 mL, and 20 mL.

• Vials can have different shapes, such as cylindrical or conical.

• Some vials have special features like screw caps, snap caps, or dropper tips.

• In the medical field, vials are used for storing medications, vaccines, an...read more

Accuracy can be achieved by ensuring precision and correctness in tasks.

• Double-checking work for errors

• Using tools or technology to assist in accuracy

• Following established procedures and guidelines

• Seeking feedback and clarification when unsure

• Regular training and practice to improve accuracy

Forced degradation is the process of intentionally subjecting a drug substance or product to stress conditions to accelerate degradation and study degradation pathways.

• Forced degradation helps in understanding the stability of a drug under different conditions.

• It involves exposing the drug to various stress factors like heat, light, humidity, and pH.

• The degradation products formed are analyzed to determine the degradation pathways and potential impurities.

• The results of force...read more

Performing LOQ involves determining the lowest concentration of a substance that can be reliably measured.

• Prepare a series of samples with known concentrations of the substance.

• Analyze the samples using the chosen analytical method.

• Identify the lowest concentration at which the signal-to-noise ratio is acceptable.

• Calculate the LOQ based on the criteria established for the method.

• Verify the LOQ through validation studies.

• Example: Determining the LOQ of a drug in a biological s...read more

Media fill is a process of simulating aseptic manufacturing conditions to test the sterility of a product.

• Media fill involves filling sterile media into containers under aseptic conditions.

• The filled containers are then incubated to check for any microbial growth.

• Media fill is used to validate the aseptic manufacturing process and ensure product sterility.

• It is a regulatory requirement for pharmaceutical and biotech companies.

• Examples of products that undergo media fill inclu...read more