Lincoln Pharmaceuticals Quality Controller Interview Questions and Answers

To convert reverse phase to normal phase in HPLC, change the stationary phase from non-polar to polar.

• Replace the non-polar stationary phase with a polar one

• Use a polar mobile phase

• Adjust the pH of the mobile phase to match the pKa of the analyte

• Optimize the gradient elution conditions

• Verify the separation using appropriate standards

The flow of water, methanol, and isopropanol can be determined by measuring their respective viscosities and densities.

• Viscosity and density of each liquid must be measured

• The flow rate can be calculated using the Hagen-Poiseuille equation

• The flow rate will vary depending on the pipe diameter and pressure

• The flow rate can be optimized by adjusting the pipe diameter and pressure

• The flow rate of each liquid can be compar

There is no magic solution.

• There is no one-size-fits-all solution for quality control.

• Quality control requires a combination of various techniques and processes.

• Continuous improvement and adaptation are key in quality control.

• Examples of quality control techniques include statistical process control, Six Sigma, and Lean manufacturing.

To convert reverse phase to normal phase in HPLC, change the stationary phase from non-polar to polar.

• Replace the non-polar stationary phase with a polar one

• Use a polar mobile phase

• Adjust the pH of the mobile phase to match the pKa of the analyte

• Optimize the gradient elution conditions

• Verify the separation using appropriate standards

The flow of water, methanol, and isopropanol can be determined by measuring their respective viscosities and densities.

• Viscosity and density of each liquid must be measured

• The flow rate can be calculated using the Hagen-Poiseuille equation

• The flow rate will vary depending on the pipe diameter and pressure

• The flow rate can be optimized by adjusting the pipe diameter and pressure

• The flow rate of each liquid can be compar

There is no magic solution.

• There is no one-size-fits-all solution for quality control.

• Quality control requires a combination of various techniques and processes.

• Continuous improvement and adaptation are key in quality control.

• Examples of quality control techniques include statistical process control, Six Sigma, and Lean manufacturing.