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OOS investigation procedure involves identifying, documenting, and resolving deviations in quality control processes.
Initiate investigation promptly upon observing an OOS result
Document all relevant information including sample details, testing procedures, and environmental conditions
Conduct root cause analysis to determine the reason for the OOS result
Implement corrective and preventive actions to address the roo...
Empower3 software uses various integration methods and tools for data analysis.
Empower3 software offers integration methods such as peak detection, peak integration, and peak area calculation.
Tools like Empower 3 Chromatography Data Software are commonly used for integration in chromatography analysis.
Integration methods in Empower3 software help in accurately quantifying compounds in samples.
Empower3 software all...
Calibration parameters for HPLC include wavelength accuracy, linearity, resolution, and peak symmetry.
Wavelength accuracy: Ensuring the detector is accurately measuring the wavelength of the sample.
Linearity: Verifying that the detector response is linear over a range of concentrations.
Resolution: Assessing the ability of the HPLC system to separate peaks of interest.
Peak symmetry: Checking the symmetry of peaks t...
Deviation in quality control refers to a departure from standard procedures or specifications. There are two main types of deviations - major and minor.
Deviation is a departure from standard procedures or specifications
Major deviations are significant and can impact product quality or safety
Minor deviations are less significant and may not impact product quality or safety
Examples of deviations include equipment ma...
Yes, I am currently handling Out of Trend (OOT) investigations in my role as QC Executive.
Yes, I have experience in identifying OOT results and conducting thorough investigations to determine the root cause.
I have worked on implementing corrective and preventive actions to prevent future OOT occurrences.
I have also collaborated with cross-functional teams to address OOT issues and ensure compliance with regulatory...
There are two main types of columns used in chromatography: packed columns and capillary columns.
Packed columns are filled with a stationary phase material, such as silica or polymer beads.
Capillary columns have a thin film coating on the inner surface, which serves as the stationary phase.
Examples include gas chromatography columns, liquid chromatography columns, and ion exchange columns.
System suitability parameters are criteria used to ensure that an analytical method is suitable for its intended purpose.
System suitability parameters include resolution, peak symmetry, retention time, and tailing factor.
These parameters are used to assess the performance of an analytical method and ensure reliable and accurate results.
For example, in chromatography, system suitability parameters are used to evalu...
Handling a hydrogen reactor requires proper training, safety precautions, and monitoring.
Ensure all personnel are properly trained in handling hydrogen and reactor operations
Implement strict safety protocols to prevent accidents or leaks
Regularly monitor reactor performance and hydrogen levels to ensure safe operation
Have emergency response plans in place in case of any incidents
Consider using automated systems fo...
Calibration procedure of HPLC involves preparing standard solutions, injecting them into the system, and plotting a calibration curve.
Prepare standard solutions of known concentration
Inject the solutions into the HPLC system
Plot a calibration curve using the peak areas or heights
Determine the equation of the line of best fit
Use the equation to calculate the concentration of unknown samples
Calibration procedure involves setting up and adjusting equipment to ensure accurate measurements.
Calibration involves comparing measurements of two instruments, one with a known magnitude and the other with unknown magnitude.
Parameters for calibration include temperature, pressure, voltage, etc.
Calibration procedures should be documented and followed regularly to maintain accuracy.
Examples of calibration paramete...
I appeared for an interview before May 2024, where I was asked the following questions.
Handling a hydrogen reactor requires proper training, safety precautions, and monitoring.
Ensure all personnel are properly trained in handling hydrogen and reactor operations
Implement strict safety protocols to prevent accidents or leaks
Regularly monitor reactor performance and hydrogen levels to ensure safe operation
Have emergency response plans in place in case of any incidents
Consider using automated systems for bet...
I applied via Referral and was interviewed before Oct 2023. There was 1 interview round.
Calibration parameters for HPLC include wavelength accuracy, linearity, resolution, and peak symmetry.
Wavelength accuracy: Ensuring the detector is accurately measuring the wavelength of the sample.
Linearity: Verifying that the detector response is linear over a range of concentrations.
Resolution: Assessing the ability of the HPLC system to separate peaks of interest.
Peak symmetry: Checking the symmetry of peaks to ens...
Empower3 software uses various integration methods and tools for data analysis.
Empower3 software offers integration methods such as peak detection, peak integration, and peak area calculation.
Tools like Empower 3 Chromatography Data Software are commonly used for integration in chromatography analysis.
Integration methods in Empower3 software help in accurately quantifying compounds in samples.
Empower3 software allows f...
OOS investigation procedure involves identifying, documenting, and resolving deviations in quality control processes.
Initiate investigation promptly upon observing an OOS result
Document all relevant information including sample details, testing procedures, and environmental conditions
Conduct root cause analysis to determine the reason for the OOS result
Implement corrective and preventive actions to address the root cau...
Yes, I am currently handling Out of Trend (OOT) investigations in my role as QC Executive.
Yes, I have experience in identifying OOT results and conducting thorough investigations to determine the root cause.
I have worked on implementing corrective and preventive actions to prevent future OOT occurrences.
I have also collaborated with cross-functional teams to address OOT issues and ensure compliance with regulatory requ...
Deviation in quality control refers to a departure from standard procedures or specifications. There are two main types of deviations - major and minor.
Deviation is a departure from standard procedures or specifications
Major deviations are significant and can impact product quality or safety
Minor deviations are less significant and may not impact product quality or safety
Examples of deviations include equipment malfunc...
I applied via Approached by Company and was interviewed in Dec 2022. There were 3 interview rounds.
I applied via Referral and was interviewed before Apr 2023. There was 1 interview round.
System suitability parameters are criteria used to ensure that an analytical method is suitable for its intended purpose.
System suitability parameters include resolution, peak symmetry, retention time, and tailing factor.
These parameters are used to assess the performance of an analytical method and ensure reliable and accurate results.
For example, in chromatography, system suitability parameters are used to evaluate t...
There are two main types of columns used in chromatography: packed columns and capillary columns.
Packed columns are filled with a stationary phase material, such as silica or polymer beads.
Capillary columns have a thin film coating on the inner surface, which serves as the stationary phase.
Examples include gas chromatography columns, liquid chromatography columns, and ion exchange columns.
The range of pH values is from 0 to 14, with 7 being neutral.
pH values below 7 are acidic, with 0 being the most acidic
pH values above 7 are alkaline or basic, with 14 being the most basic
A pH of 7 is considered neutral, neither acidic nor basic
Calibration procedure involves setting up and adjusting equipment to ensure accurate measurements.
Calibration involves comparing measurements of two instruments, one with a known magnitude and the other with unknown magnitude.
Parameters for calibration include temperature, pressure, voltage, etc.
Calibration procedures should be documented and followed regularly to maintain accuracy.
Examples of calibration parameters: z...
HPLC uses a variety of lamps depending on the application.
UV-Vis lamps are commonly used for detecting analytes in HPLC
Fluorescence lamps are used for detecting fluorescent analytes
Pulsed amperometric detection (PAD) uses a gold electrode and a mercury lamp
Diode array detectors (DAD) use a deuterium lamp and a tungsten lamp
The type of lamp used depends on the specific HPLC application
I applied via Referral and was interviewed in Aug 2021. There was 1 interview round.
There are various types of training that can be provided to employees.
On-the-job training
Classroom training
Online training
Simulation training
Mentoring and coaching
Cross-training
Team training
Leadership training
Calibration procedure of HPLC involves preparing standard solutions, injecting them into the system, and plotting a calibration curve.
Prepare standard solutions of known concentration
Inject the solutions into the HPLC system
Plot a calibration curve using the peak areas or heights
Determine the equation of the line of best fit
Use the equation to calculate the concentration of unknown samples
I applied via Recruitment Consultant and was interviewed before Apr 2020. There were 3 interview rounds.
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I applied via Walk-in and was interviewed before Jan 2019. There were 3 interview rounds.
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