Senior Medical Reviewer

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Senior Medical Reviewer Interview Questions and Answers

Updated 30 Mar 2024

Q1. Mechanism of action of a drug that you are currently working on

Ans.

The drug works by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, leading to vasodilation and decreased blood pressure.

  • Inhibits angiotensin-converting enzyme (ACE)

  • Prevents conversion of angiotensin I to angiotensin II

  • Results in vasodilation and decreased blood pressure

Q2. Difference between unassessable and conditional causality assessment

Ans.

Unassessable causality assessment means the relationship between a drug and an adverse event cannot be determined, while conditional causality assessment means the relationship is possible under certain conditions.

  • Unassessable causality assessment: unable to determine relationship between drug and adverse event

  • Conditional causality assessment: relationship is possible under certain conditions

  • Example: Unassessable - patient has multiple medical conditions, making it difficult ...read more

Q3. WHO classification of causality assessment.

Ans.

WHO classification of causality assessment is a method used to determine the likelihood of a causal relationship between a drug and an adverse event.

  • WHO classification includes categories like certain, probable, possible, unlikely, conditional/unclassified, and unassessable/unclassifiable.

  • It helps in determining the strength of evidence linking a drug to an adverse event.

  • Example: If a patient develops liver injury after taking a medication and there is a known association bet...read more

Q4. Difference between severity and seriousness

Ans.

Severity refers to the intensity of a medical condition, while seriousness refers to the potential impact or consequences of the condition.

  • Severity is the extent to which a medical condition affects an individual's health or quality of life.

  • Seriousness is the potential for a medical condition to result in significant harm or complications.

  • Severity is often measured on a scale (e.g. mild, moderate, severe), while seriousness considers the potential outcomes of the condition.

  • Fo...read more

Senior Medical Reviewer Jobs

Senior Medical Reviewer 2-5 years
Novo Nordisk Centre (India) Pvt Ltd
4.1
Bangalore / Bengaluru
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