10+ Accacia Interview Questions and Answers

There are 11 body systems in the human body.

• The circulatory system includes the heart, blood vessels, and blood.

• The respiratory system involves the lungs and airways.

• The digestive system includes the stomach, intestines, and liver.

• The nervous system consists of the brain, spinal cord, and nerves.

• The musculoskeletal system involves the muscles, bones, and joints.

• The endocrine system includes glands like the thyroid and adrenal glands.

• The reproductive system involves organs lik...read more

The formula for tailing factor according to USP is (w0.5 - w0) / w0.5, where w0.5 is the width at half height and w0 is the width at baseline.

• Tailing factor formula: (w0.5 - w0) / w0.5

• w0.5 is the width at half height of the peak

• w0 is the width at baseline of the peak

The glass liner in a Gas Chromatograph serves as a protective barrier between the sample and the instrument components.

• Glass liner prevents contamination of the instrument components by the sample being analyzed.

• It helps in maintaining the integrity of the sample by preventing interactions with the instrument surfaces.

• Glass liners are replaceable and can be easily cleaned to ensure accurate and reliable results.

• They also help in reducing carryover effects between different sa...read more

Peak to Valley ratio formula is (Peak height - Valley height) / Valley height. It is used in chromatography to measure the separation efficiency.

• Peak to Valley ratio formula: (Peak height - Valley height) / Valley height

• It is used in chromatography to quantify the separation efficiency of peaks in a chromatogram

• A higher Peak to Valley ratio indicates better separation of peaks

• It helps in determining the resolution of peaks in chromatography

• Example: If a peak has a height of 1...read more

The formula for Resolution according to USP is (Rs) = 2*(tR2 - tR1) / (w1 + w2), where Rs is the resolution, tR1 and tR2 are the retention times of the two peaks, and w1 and w2 are the peak widths.

• Resolution formula: Rs = 2*(tR2 - tR1) / (w1 + w2)

• Rs is the resolution between two peaks

• tR1 and tR2 are the retention times of the two peaks

• w1 and w2 are the peak widths

Critical parameters in BMR and BPR

• Critical parameters in BMR include temperature, pH, agitation rate, and dissolved oxygen level

• Critical parameters in BPR include temperature, pressure, mixing speed, and gas flow rate

• Monitoring and controlling these parameters is essential for ensuring product quality and consistency

Process monitoring in manufacturing and packing involves closely observing and controlling the various stages of production to ensure quality and efficiency.

• Monitoring the parameters and variables that affect the manufacturing and packing processes

• Regularly checking and recording data such as temperature, pressure, and time

• Using statistical process control techniques to analyze data and identify trends or deviations

• Implementing corrective actions when necessary to maintain pr...read more

OOS and OOT refer to Out of Specification and Out of Trend, respectively, in quality control processes.

• OOS (Out of Specification) occurs when a product fails to meet one or more of its quality specifications.

• OOT (Out of Trend) refers to a situation where a product's quality parameters are trending towards a failure point.

• Both OOS and OOT require thorough investigation to determine the root cause and implement corrective actions.

• Documentation of the investigation process and a...read more

The current versions of IP, USP, and NF are IP 2020, USP 43-NF 38, and NF 38, respectively.

• IP stands for Indian Pharmacopoeia and the current version is IP 2020.

• USP stands for United States Pharmacopeia and the current version is USP 43-NF 38.

• NF stands for National Formulary and the current version is NF 38.

• These are all official compendia that provide standards for the identity, strength, quality, and purity of medicines.

• They are used by regulatory agencies, manufacturers, a...read more