Unichem Laboratories Research and Development Interview Questions and Answers

Q1. Principles of hplc, gc, ir
Ans. 
Principles of HPLC, GC, and IR involve separation of compounds based on different physical and chemical properties.
• HPLC (High Performance Liquid Chromatography) separates compounds based on their affinity for the stationary phase and mobile phase.

• GC (Gas Chromatography) separates compounds based on their boiling points and affinity for the stationary phase.

• IR (Infrared Spectroscopy) identifies compounds based on their ...read more
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Q2. Difference between roi and lod
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ROI stands for Return on Investment, while LOD stands for Limit of Detection.
• ROI is a financial metric used to evaluate the efficiency or profitability of an investment.

• LOD is the lowest concentration of a substance that can be reliably detected by a particular analytical procedure.

• ROI is typically expressed as a percentage, representing the ratio of net profit to the initial investment.

• LOD is important in analytical c...read more
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Q1. Expected salary
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About drugs mostly based on pharmaceutical

Q1. Molarity of Hcl
Ans. 
Molarity of HCl is a measure of concentration of hydrochloric acid in a solution.
• Molarity is defined as the number of moles of solute per liter of solution.

• To calculate molarity, divide the number of moles of solute by the volume of the solution in liters.

• For example, if you have 0.5 moles of HCl in 1 liter of solution, the molarity would be 0.5 M.
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Q2. Forced degradation
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Q1. What is polarity and how it effect the molecules
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Polarity refers to the separation of electric charge within a molecule, which affects its chemical properties.
• Polarity is determined by the difference in electronegativity between atoms in a molecule.

• Polar molecules have a positive and negative end, while nonpolar molecules have an even distribution of charge.

• Polarity influences various properties of molecules, such as solubility, boiling point, and intermolecular forc...read more
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Q2. Types of chromatography
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Chromatography is a technique used to separate and analyze mixtures of substances based on their different interactions with a stationary phase and a mobile phase.
• Gas chromatography (GC) separates volatile compounds based on their vapor pressure and affinity for the stationary phase.

• Liquid chromatography (LC) separates compounds based on their polarity and affinity for the stationary phase.

• Ion exchange chromatography s...read more
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Q3. Chiral compound and its characteristics
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Chiral compounds are molecules that have a non-superimposable mirror image.
• Chiral compounds have an asymmetric carbon atom, also known as a chiral center.

• They exist in two enantiomeric forms, which are mirror images of each other.

• Chiral compounds exhibit optical activity, meaning they rotate the plane of polarized light.

• They have different physical and chemical properties from their mirror images.

• Examples of chiral com...read more
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Q1. Pharma related questions
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Q1. Anticancer activity
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Q2. Cancer cell line
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Q1. About instument
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Q2. About instrument knowledge
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Q3. Kf gc hplc validation
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Q1. Salary discussion
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Q2. Good hr department
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Q1. Who are you, why you want this job
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Q2. What do you expect from us
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Q1. How are you, Are you feeling ok
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Q2. How much salary you expect why should we offer you that
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