Uni Medicolabs QC Chemist Interview Questions and Answers

Total 30 Questions (15 Aptitude and 15 Technical Questions)

Q1. Any Nameing reaction Mechanism
Ans. 
The Grignard reaction involves the addition of an organomagnesium halide to a carbonyl group.
• The reaction is named after French chemist Victor Grignard.

• It is used to form carbon-carbon bonds and is a key reaction in organic synthesis.

• An example is the synthesis of triphenylmethanol from benzophenone and phenylmagnesium bromide.

• The reaction proceeds through the formation of a Grignard reagent, which then attacks the car...read more
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Q2. What is Titration, What is pH
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Titration is a technique to determine the concentration of a substance in a solution. pH is a measure of acidity or basicity of a solution.
• Titration involves adding a solution of known concentration to a solution of unknown concentration until the reaction is complete.

• pH is measured on a scale of 0-14, with 7 being neutral, below 7 acidic, and above 7 basic.

• Titration can be used to determine the concentration of acids,...read more
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Q1. Waiting For 2 Months
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Q1. About Related substance
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Q2. About Dissolution
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Q3. About Assay of FP
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Q4. About Average Value
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Q5. About trouble shooting
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Q1. About Package itself
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Q2. About Experience
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Q1. What is wt. Veriation criteria as per ip &USP
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Q2. Line clearance in compression area
Ans. 
Line clearance in compression area is essential to prevent cross-contamination and ensure product quality.
• Line clearance involves removing any previous product residues, cleaning equipment, and verifying cleanliness before starting a new batch.

• It helps prevent mix-ups, contamination, and errors during production.

• Examples of line clearance activities include visual inspection, swab testing, and documentation of cleaning...read more
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Q1. Chemical Name and formula
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Chemical name and formula are identifiers for specific chemical compounds.
• Chemical name is the common name given to a chemical compound.

• Chemical formula represents the elements and their ratios in a compound.

• Example: Water - Chemical name, H2O - Chemical formula.
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Q2. How to make 0.1M HCL
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To make 0.1M HCL, dilute concentrated hydrochloric acid with water.
• Dilute 1 part of concentrated HCL with 9 parts of water to make 0.1M HCL solution.

• Always add acid to water slowly to prevent splashing and heat generation.

• Use proper protective equipment such as gloves and goggles when handling acids.
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HPLc,GC, IR,UV,And basic chemistry related questions

Q1. Trouble shooting of HPLC
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Troubleshooting of HPLC involves identifying and resolving issues with the high-performance liquid chromatography system.
• Check for leaks in the system and tighten connections if necessary.

• Inspect and clean the columns regularly to ensure optimal performance.

• Calibrate the detector and pump to maintain accuracy of results.

• Troubleshoot error messages on the HPLC software by checking system settings and parameters.

• Consult ...read more
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Q2. Why use caffeine for calibration of HPLC
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Caffeine is used for calibration of HPLC due to its well-defined retention time and peak shape.
• Caffeine has a well-defined retention time, making it easy to identify and calibrate the HPLC system.

• Caffeine produces a sharp and symmetrical peak, which helps in accurately determining the system's performance.

• It is a commonly used compound for calibration in HPLC due to its stability and reproducibility.

• Using caffeine as a...read more
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