Gralit India Biotech Interview Questions and Answers

NGS principles involve variant detection through sequencing and analysis of DNA or RNA samples.

• NGS (Next Generation Sequencing) is a high-throughput technology used for DNA or RNA sequencing.

• Variant detection involves identifying differences in DNA or RNA sequences compared to a reference genome.

• NGS principles include library preparation, sequencing, and bioinformatics analysis.

• Variant calling algorithms are used to id...read more

Variant calling is a process of identifying differences between a sample and a reference genome.

• Variant calling is used in genomics to identify genetic variations that may be associated with disease or other traits.

• It involves comparing a sample genome to a reference genome to identify differences, or variants, such as single nucleotide polymorphisms (SNPs) or insertions/deletions (indels).

• Variant calling can be done u...read more