DIVI'S Laboratories Quality Analyst Interview Questions and Answers

Data integrity refers to the accuracy, consistency, and reliability of data throughout its lifecycle.

• Data integrity ensures that data remains unchanged and reliable over time.

• It involves maintaining the accuracy and consistency of data during storage, processing, and transmission.

• Data integrity can be achieved through various measures such as checksums, encryption, and access controls.

• Examples of data integrity issues ...read more

CAPA stands for Corrective and Preventive Action.

• CAPA is a systematic approach to identify, investigate, and resolve quality issues.

• It involves analyzing the root cause of the problem and implementing corrective actions to prevent recurrence.

• CAPA is commonly used in industries such as manufacturing, pharmaceuticals, and healthcare.

• Examples of CAPA tools and techniques include 5 Whys, Fishbone Diagrams, and Pareto Analy

Calibration is required to ensure accuracy and consistency of measurements and equipment.

• Calibration helps to maintain the quality of products and services.

• It ensures that measurements are accurate and consistent, reducing errors and improving efficiency.

• Calibration is necessary for compliance with industry standards and regulations.

• Examples of equipment that require calibration include scales, thermometers, and medica...read more

I would clarify the reason behind the request and discuss any potential impact on the analysis.

• Ask for clarification on the reason for skipping the step

• Discuss any potential impact on the analysis

• Provide alternative solutions if possible

I am seeking new opportunities to grow professionally and expand my skill set.

• Looking for a company that values continuous learning and development

• Seeking a more challenging and dynamic work environment

• Want to work with a team that promotes collaboration and innovation

• Desire to explore new technologies and methodologies

• Seeking better career growth prospects and opportunities for advancement

I have 5 years of experience as a Quality Analyst.

• I have worked in various industries, including software development and manufacturing.

• I am proficient in using quality assurance tools and techniques.

• I have experience in conducting quality audits and inspections.

• I have successfully implemented quality improvement initiatives.

• I have strong analytical and problem-solving skills.

• I have excellent communication and document...read more

Yes, I know integration.

• Integration is the process of combining different components or systems to work together seamlessly.

• It involves testing the interfaces between the components to ensure they communicate effectively.

• Examples of integration include integrating a payment gateway into an e-commerce website or integrating a CRM system with a marketing automation tool.

There are different types of integration such as vertical, horizontal, forward, backward, and bi-directional.

• Vertical integration involves the integration of different levels of the same supply chain.

• Horizontal integration involves the integration of different companies at the same level of the supply chain.

• Forward integration involves the integration of a company with its distributors or retailers.

• Backward integration...read more

RSD stands for Relative Standard Deviation and is a measure of the variability of a sample compared to its mean.

• RSD is calculated by dividing the standard deviation of a sample by its mean and multiplying by 100.

• It is expressed as a percentage and is often used in analytical chemistry to assess the precision of a method.

• A low RSD indicates that the data is precise and consistent, while a high RSD indicates that the dat...read more

System suitability parameters for HPLC ensure the proper functioning of the system and accuracy of results.

• Retention time of the analyte

• Resolution between peaks

• Theoretical plates

• Peak symmetry factor

• Limit of detection and quantification

• Accuracy and precision of the system

• Mobile phase composition and pH

• Column temperature and pressure

• Flow rate and injection volume

Dissolution is the process by which a solid substance dissolves in a solvent to form a solution.

• The first stage is the wetting stage, where the solid substance comes into contact with the solvent.

• The second stage is the dissolution stage, where the solid substance dissolves in the solvent.

• The third stage is the diffusion stage, where the dissolved substance diffuses away from the solid surface into the bulk of the solv...read more

System suitability for HPLC refers to the ability of the system to provide accurate and precise results consistently.

• System suitability tests are performed to ensure that the HPLC system is working properly.

• Parameters such as resolution, peak symmetry, and retention time are evaluated.

• Acceptance criteria are established based on the method being used.

• Examples of system suitability tests include replicate injections, st...read more

Troubleshooting for HPLC

• Check for leaks in the system

• Verify the column is properly installed and conditioned

• Ensure the mobile phase is properly prepared and filtered

• Check for air bubbles in the system

• Verify the detector is properly calibrated

• Inspect the sample preparation process

• Check for any software or hardware malfunctions

UV spectrophotometer principle and calibration

• UV spectrophotometer measures the absorbance or transmittance of light in the UV range

• Principle: It uses a UV light source to pass light through a sample and measures the intensity of light before and after passing through the sample

• Calibration: Involves setting the instrument to zero absorbance with a blank solution and verifying accuracy with known standard solutions

• Calib...read more