Concept Pharmaceuticals Chemist Interview Questions and Answers

Potassium iodide (KI) is commonly used in Karl Fischer (KF) titration.

• Potassium iodide (KI) is added to the Karl Fischer reagent to enhance the solubility of water.

• KI reacts with water to form iodine, which is then titrated with the Karl Fischer reagent.

• The reaction between KI and water in KF titration is as follows: KI + SO2 + H2O → KHSO4 + I2

• The iodine formed is then quantitatively determined by titration with the Ka...read more

HPLC is a technique used to separate, identify, and quantify components in a mixture.

• HPLC stands for High Performance Liquid Chromatography.

• It is commonly used in pharmaceuticals, food and beverage, and environmental testing.

• HPLC can separate and quantify complex mixtures of compounds.

• It can be used to detect impurities in drugs and determine their concentration.

• HPLC can also be used to analyze the composition of food ...read more

FTIR is a powerful analytical technique used for identifying and quantifying chemical compounds.

• Advantages: non-destructive, rapid, requires minimal sample preparation, can analyze a wide range of compounds, can be used for qualitative and quantitative analysis

• Disadvantages: expensive equipment, requires trained personnel, may require calibration, may not be suitable for analyzing certain compounds

• Example: FTIR can be ...read more