30+ Chemist Quality Control Interview Questions and Answers

A detector is used in gas chromatography to measure the concentration of analytes in the sample.

• The detector is an essential component of a gas chromatography system.

• It detects and quantifies the separated components of a sample.

• Different types of detectors are used, such as flame ionization detector (FID), thermal conductivity detector (TCD), and electron capture detector (ECD).

• The choice of detector depends on the specific analytes being measured.

• Detectors provide a signal ...read more

Boling point tungsten does not exist as tungsten has a very high melting point.

• Tungsten has a melting point of 3422°C, which is the highest of all metals.

• The boiling point of tungsten is not applicable as it does not exist in a liquid state under normal conditions.

• Tungsten is commonly used in high-temperature applications such as light bulb filaments and rocket nozzles.

We use Karl Fischer Titrator for moisture analysis. The make and software depend on the model.

• Karl Fischer Titrator is used for moisture analysis

• The make and software depend on the model being used

• Some common makes are Metrohm, Mettler Toledo, and Hanna Instruments

• Common software includes Tiamo and Volumetric Karl Fischer Titration software

The pH range in drinking water typically falls between 6.5 and 8.5.

• The pH range in drinking water is important for maintaining water quality and safety.

• A pH below 6.5 may indicate acidic water, while a pH above 8.5 may indicate alkaline water.

• The ideal pH range for drinking water is generally considered to be between 6.5 and 8.5.

• pH levels outside this range may affect the taste, odor, and safety of the water.

• For example, acidic water with a low pH may corrode pipes, while alk...read more

Bases are used in laboratories for various purposes, including pH adjustment, neutralization reactions, and synthesis of chemicals.

• Bases are substances that can accept protons or donate pairs of electrons.

• They are commonly used to adjust the pH of solutions by neutralizing acidic substances.

• Bases are also used in neutralization reactions to convert acids into salts and water.

• In chemical synthesis, bases are often employed as catalysts or reactants.

• Examples of bases commonly u...read more

Maintain workability & quality by proper planning, monitoring, testing, and communication.

• Develop a detailed quality control plan outlining procedures and specifications.

• Regularly monitor and test materials and processes to ensure compliance with standards.

• Communicate effectively with all stakeholders to address any issues or changes in requirements.

• Implement corrective actions promptly to maintain quality and workability.

• Train and educate staff on quality control measures an...read more

Pharma companies use machines to produce drugs. API is the active ingredient in a drug. R&D is the research and development of new drugs.

• Pharma companies use various machines like mixers, reactors, and centrifuges to produce drugs.

• API is the active ingredient in a drug that produces the desired effect on the body.

• R&D is the process of discovering and developing new drugs through research and testing.

• Pharma companies invest heavily in R&D to create new drugs that can treat var...read more

Handle customer complaints by listening, empathizing, investigating, resolving, and following up.

• Listen actively to the customer's concerns without interrupting

• Empathize with the customer and acknowledge their frustration

• Investigate the issue thoroughly to understand the root cause

• Resolve the issue promptly and effectively, offering solutions or compensation if necessary

• Follow up with the customer to ensure their satisfaction and prevent future issues

The strongest acids commonly used in laboratories are sulfuric acid, hydrochloric acid, and nitric acid.

• Sulfuric acid (H2SO4) is a highly corrosive and strong acid commonly used in various laboratory applications.

• Hydrochloric acid (HCl) is another strong acid frequently used in laboratories for pH adjustment and chemical reactions.

• Nitric acid (HNO3) is a powerful acid used for various purposes, including metal etching and cleaning.

• Other strong acids include phosphoric acid (H...read more

Titration is a technique used to determine the concentration of a solution by reacting it with a solution of known concentration.

• Titration involves adding a solution of known concentration (the titrant) to a solution of unknown concentration until a reaction is complete.

• The point at which the reaction is complete is called the endpoint.

• The endpoint is usually detected using an indicator, which changes color when the reaction is complete.

• Titration can be used to determine the ...read more

The package for annum refers to the unit of time equal to one year.

• Annum is a Latin term meaning 'year'.

• In the context of chemistry, the package for annum is used to express rates or frequencies over a period of one year.

• For example, the decay rate of a radioactive substance may be measured in disintegrations per annum.

ICP-OES is a technique used to determine the elemental composition of a sample by measuring the intensity of light emitted by the sample.

• ICP-OES stands for Inductively Coupled Plasma Optical Emission Spectroscopy

• It works by ionizing the sample with plasma and then measuring the light emitted by the excited ions

• The intensity of the light is proportional to the concentration of the element in the sample

• ICP-OES is commonly used in environmental analysis, pharmaceuticals, and met...read more

A buffer solution is a solution that resists changes in pH when small amounts of acid or base are added.

• Buffer solutions are made up of a weak acid and its conjugate base or a weak base and its conjugate acid.

• They are commonly used in chemical and biological experiments to maintain a stable pH.

• Examples of buffer solutions include acetic acid/sodium acetate buffer and phosphate buffer.

• Buffer capacity is the amount of acid or base that can be added to a buffer solution without ...read more

Efficient supply to customers can be achieved by optimizing inventory management, streamlining production processes, and utilizing technology.

• Optimize inventory management by implementing just-in-time inventory system

• Streamline production processes to reduce lead times and increase production capacity

• Utilize technology such as automated ordering systems and real-time tracking for better supply chain visibility

Aluminium is a versatile metal with various uses in industries such as construction, transportation, packaging, and electronics.

• Used in construction for windows, doors, roofing, and siding

• Used in transportation for car parts, airplane parts, and bicycle frames

• Used in packaging for cans, foils, and containers

• Used in electronics for wiring, heat sinks, and computer parts

IS code for testing of raw materials is essential for quality control in chemistry.

• IS 3400: Methods for testing of raw materials for the paint industry

• IS 1708: Methods for testing of raw materials for the rubber industry

• IS 5402: Methods for testing of raw materials for the pharmaceutical industry

EDXRF stands for Energy Dispersive X-ray Fluorescence. It is a non-destructive analytical technique used for elemental analysis.

• EDXRF measures the characteristic X-rays emitted by a sample when it is bombarded with high-energy X-rays.

• The energy of the emitted X-rays is characteristic of the elements present in the sample.

• EDXRF can be used for qualitative and quantitative analysis of a wide range of elements.

• It is commonly used in materials science, environmental analysis, and...read more

Various metal alloys are possible depending on the combination of metals used.

• Metal alloys are created by combining two or more metals.

• Common metal alloys include brass (copper and zinc), bronze (copper and tin), and steel (iron and carbon).

• Alloys can also be created using non-metal elements such as silicon and boron.

• The properties of the resulting alloy depend on the metals used and their proportions.

HPLC principle is based on the separation of components in a mixture using high pressure to force the mixture through a column filled with a stationary phase.

• HPLC stands for High Performance Liquid Chromatography

• The stationary phase can be a solid or a liquid

• The mobile phase is the liquid that carries the sample through the column

• The separation is based on the differences in the components' interactions with the stationary phase

• HPLC is commonly used in pharmaceuticals, food a...read more

Indicators are used in quality control to determine the endpoint of a reaction or to indicate the presence of a specific substance.

• Indicators are used in titrations to determine the endpoint of a reaction.

• They can also be used to indicate the presence of a specific substance in a sample.

• Common indicators include litmus paper, phenolphthalein, and methyl orange.

• Indicators can be organic compounds or inorganic compounds.

• The choice of indicator depends on the type of reaction be...read more

IS code of Slump Testing is IS: 1199-1959

• IS code for Slump Testing is IS: 1199-1959

• Slump test is conducted to measure the workability of concrete

• The test involves filling a slump cone with concrete, then removing the cone and measuring the amount of slump

Quality person selection involves a thorough screening process to identify the most suitable candidate for the job.

• Define the job requirements and qualifications

• Create a job description and post it on relevant job boards

• Review resumes and cover letters to identify potential candidates

• Conduct phone and in-person interviews to assess skills and personality

• Check references and conduct background checks

• Make an offer to the most qualified candidate

Water is a transparent, tasteless, odorless, and nearly colorless chemical substance.

• Water is composed of two hydrogen atoms and one oxygen atom, chemically known as H2O.

• It is essential for all known forms of life and is the most abundant substance on Earth.

• Water exists in three states: solid (ice), liquid (water), and gas (water vapor).

• It has a high specific heat capacity, making it an effective heat regulator.

• Water is a universal solvent, capable of dissolving many substanc...read more

Managing cost/m³ involves optimizing processes, reducing waste, and negotiating with suppliers.

• Optimize processes to increase efficiency and reduce costs

• Reduce waste by implementing recycling programs or using raw materials more efficiently

• Negotiate with suppliers for better pricing or discounts

• Monitor and track expenses to identify areas for cost savings

• Implement cost-saving measures such as bulk purchasing or outsourcing certain tasks

Site sampling can be managed by following proper protocols, ensuring representative samples, and maintaining accurate records.

• Develop a sampling plan outlining the objectives, methods, and locations for sampling.

• Use appropriate sampling techniques to ensure representative samples are collected.

• Follow standard operating procedures for sample collection, handling, and storage.

• Maintain accurate records of sampling activities, including dates, times, locations, and sample identif...read more

GC principal refers to the principle of gas chromatography, which involves separating and analyzing components of a mixture based on their affinity for a stationary phase and a mobile phase.

• Gas chromatography (GC) is a technique used to separate and analyze volatile compounds in a mixture.

• The principle of GC involves the use of a stationary phase (typically a solid or liquid) and a mobile phase (usually a gas) to separate the components of the mixture.

• The components of the mi...read more

Cube sampling is a method used to collect representative samples from a larger batch or population.

• Cube sampling involves dividing a larger batch or population into smaller cubes or sections.

• Random cubes are then selected for sampling to ensure representativeness.

• This method is commonly used in industries like pharmaceuticals, food production, and materials testing.

Acidity is the measure of the concentration of hydrogen ions in a solution.

• Acidity is measured on the pH scale, which ranges from 0 to 14.

• A pH of 7 is neutral, while a pH below 7 is acidic and above 7 is basic.

• Acidity can affect the properties and behavior of substances, such as their solubility and reactivity.

• Examples of acidic substances include vinegar, lemon juice, and battery acid.

Karlfisher reaction is a chemical method used to determine the amount of water in a sample.

• It involves the reaction of iodine with sulfur dioxide and pyridine in the presence of a solvent.

• The reaction produces iodine monochloride, which reacts with water to form hydrochloric acid and iodide ions.

• The amount of water in the sample can be determined by titrating the iodine monochloride with a standardized solution of thiosulfate.

• Karlfisher reaction is commonly used in the pharma...read more

Ion exchange chromatography separates ions based on their charge

• Separates ions based on charge

• Uses a stationary phase with charged groups to attract ions of opposite charge

• Ions are eluted by changing the pH or ionic strength of the mobile phase

• Commonly used in protein purification and analysis

LCMS stands for Liquid Chromatography Mass Spectrometry, a technique used for separation, identification, and quantification of compounds in a sample.

• LCMS combines the separation capabilities of liquid chromatography with the detection capabilities of mass spectrometry.

• It is commonly used in pharmaceutical, environmental, and forensic analysis.

• LCMS can provide information on the molecular weight, structure, and quantity of compounds in a sample.

• It is a powerful tool for ident...read more