Biotech Laboratories Quality Analyst Interview Questions and Answers

pH is a measure of acidity or alkalinity of a solution. It is measured on a scale of 0 to 14.

• pH stands for 'potential of Hydrogen'

• It is a measure of the concentration of hydrogen ions in a solution

• A pH of 7 is considered neutral, below 7 is acidic, and above 7 is alkaline

• pH can be measured using pH meters, pH paper/strips, or pH indicators

Calibration ensures accuracy of instruments by comparing measurements to a known standard.

• Calibration is the process of adjusting an instrument to ensure its measurements are accurate.

• Principles of instruments include accuracy, precision, repeatability, and reproducibility.

• Examples of calibrated instruments include thermometers, scales, and pressure gauges.

Investigation tools are used to analyze data and identify issues in software development.

• Common investigation tools include debuggers, profilers, and log analyzers.

• Debuggers help identify and fix coding errors by allowing developers to step through code and inspect variables.

• Profilers analyze the performance of code, identifying bottlenecks and areas for optimization.

• Log analyzers parse and analyze log files to identif...read more

Molarity, molality, and normality are measures of concentration in chemistry. UV range refers to the range of ultraviolet light.

• Molarity is the number of moles of solute per liter of solution.

• Molality is the number of moles of solute per kilogram of solvent.

• Normality is the number of equivalents of solute per liter of solution.

• UV range refers to the range of wavelengths of ultraviolet light, typically between 10 and 40

PDA and UV detector are both used in HPLC analysis but differ in their detection mechanism.

• PDA detector measures the entire UV-Vis spectrum of the eluent while UV detector measures at a specific wavelength.

• PDA detector can provide more information about the sample while UV detector is more sensitive and specific.

• PDA detector is more expensive than UV detector.

• PDA detector is useful for detecting impurities while UV det...read more

HPLC is a technique used to separate, identify, and quantify components in a mixture based on their interaction with a stationary phase and mobile phase.

• HPLC stands for High-Performance Liquid Chromatography.

• The principle of HPLC involves the separation of components in a mixture based on their affinity for the stationary phase and mobile phase.

• The instrumentation of HPLC includes a pump to deliver the mobile phase, a ...read more

GC stands for Gas Chromatography, a principle and instrumentation used for separating and analyzing volatile compounds.

• GC is a technique used in analytical chemistry to separate and identify components of a mixture.

• It involves injecting a sample into a gas chromatograph, which vaporizes the sample and carries it through a column.

• The column contains a stationary phase that interacts with the sample components, causing t...read more

UV spectroscopy is a technique that uses ultraviolet light to analyze the chemical composition of substances.

• UV spectroscopy is based on the principle that molecules absorb ultraviolet light at specific wavelengths.

• The Beer-Lambert law relates the concentration of a substance to the amount of light it absorbs.

• UV spectroscopy is commonly used in pharmaceutical, environmental, and forensic analysis.

• It is used to determin...read more