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HATU is used as a coupling reagent in acid amine coupling to form peptide bonds.
HATU stands for 2-(1H-7-Azabenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate
It is a highly efficient coupling reagent used in solid-phase peptide synthesis
HATU activates carboxylic acids to form reactive intermediates that can react with amines to form peptide bonds
It is preferred over other coupling reagents like DCC a...
Cross coupling reaction involves the formation of a covalent bond between two different molecules or functional groups.
It is a type of reaction used in organic chemistry to form carbon-carbon, carbon-nitrogen, or carbon-oxygen bonds.
It involves the use of a catalyst, typically a transition metal, to facilitate the reaction.
Examples include the Suzuki-Miyaura reaction, the Heck reaction, and the Stille reaction.
Cro...
Oxidative coupling reactions involve the formation of a covalent bond between two molecules through the removal of hydrogen atoms.
Involves the formation of a new covalent bond between two molecules
Typically involves the removal of hydrogen atoms
Commonly used in organic synthesis to create complex molecules
Examples include the Heck reaction and the Wacker process
Scientific knowledge encompasses facts, theories, and principles acquired through systematic study and experimentation.
Scientific knowledge is based on empirical evidence and is subject to change as new evidence is discovered
It is built upon the scientific method, which involves making observations, forming hypotheses, conducting experiments, and analyzing data
Scientific knowledge is used to explain natural phenom...
CIS and trance proton pattern in NMR refers to the orientation of protons in a molecule.
CIS refers to the protons that are on the same side of a double bond or ring in a molecule
Trans refers to the protons that are on opposite sides of a double bond or ring in a molecule
The pattern of these protons can be observed in NMR spectroscopy and can provide information about the structure of the molecule
For example, in a ...
Oxidation of alcohol to acid is a chemical reaction that involves the loss of electrons from an alcohol molecule resulting in the formation of a carboxylic acid.
The oxidation of primary alcohols results in the formation of aldehydes which are further oxidized to carboxylic acids.
Secondary alcohols are oxidized to ketones which cannot be further oxidized.
Tertiary alcohols cannot be oxidized to carboxylic acids.
Comm...
I applied via Naukri.com and was interviewed in Mar 2024. There was 1 interview round.
I appeared for an interview in Nov 2024, where I was asked the following questions.
Oxidative coupling reactions involve the formation of a covalent bond between two molecules through the removal of hydrogen atoms.
Involves the formation of a new covalent bond between two molecules
Typically involves the removal of hydrogen atoms
Commonly used in organic synthesis to create complex molecules
Examples include the Heck reaction and the Wacker process
I applied via Approached by Company and was interviewed before Nov 2022. There were 3 interview rounds.
Scientific knowledge encompasses facts, theories, and principles acquired through systematic study and experimentation.
Scientific knowledge is based on empirical evidence and is subject to change as new evidence is discovered
It is built upon the scientific method, which involves making observations, forming hypotheses, conducting experiments, and analyzing data
Scientific knowledge is used to explain natural phenomena, ...
I applied via Naukri.com and was interviewed before Jul 2023. There was 1 interview round.
I want to join Aragen because of its reputation for cutting-edge research and collaborative work environment.
Aragen is known for its innovative research projects
I am impressed by the collaborative work culture at Aragen
I believe Aragen offers great opportunities for professional growth and development
I will manage team productivity by setting clear goals, providing support and resources, fostering open communication, and monitoring progress.
Set clear goals and expectations for each team member
Provide necessary support and resources to help team members succeed
Foster open communication and encourage collaboration among team members
Monitor progress regularly and provide feedback to keep team on track
CIS and trance proton pattern in NMR refers to the orientation of protons in a molecule.
CIS refers to the protons that are on the same side of a double bond or ring in a molecule
Trans refers to the protons that are on opposite sides of a double bond or ring in a molecule
The pattern of these protons can be observed in NMR spectroscopy and can provide information about the structure of the molecule
For example, in a molec...
Oxidation of alcohol to acid is a chemical reaction that involves the loss of electrons from an alcohol molecule resulting in the formation of a carboxylic acid.
The oxidation of primary alcohols results in the formation of aldehydes which are further oxidized to carboxylic acids.
Secondary alcohols are oxidized to ketones which cannot be further oxidized.
Tertiary alcohols cannot be oxidized to carboxylic acids.
Common ox...
I applied via Referral and was interviewed before May 2022. There were 2 interview rounds.
Cross coupling reaction involves the formation of a covalent bond between two different molecules or functional groups.
It is a type of reaction used in organic chemistry to form carbon-carbon, carbon-nitrogen, or carbon-oxygen bonds.
It involves the use of a catalyst, typically a transition metal, to facilitate the reaction.
Examples include the Suzuki-Miyaura reaction, the Heck reaction, and the Stille reaction.
Cross co...
HATU is used as a coupling reagent in acid amine coupling to form peptide bonds.
HATU stands for 2-(1H-7-Azabenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate
It is a highly efficient coupling reagent used in solid-phase peptide synthesis
HATU activates carboxylic acids to form reactive intermediates that can react with amines to form peptide bonds
It is preferred over other coupling reagents like DCC and DI...
I applied via Pharma wisdom and was interviewed in Feb 2022. There were 2 interview rounds.
I applied via Naukri.com and was interviewed before Apr 2022. There were 2 interview rounds.
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