Aragen Life Sciences Junior Research Associate Interview Questions and Answers

Beckmann rearrangement is a chemical reaction that involves the conversion of an oxime to an amide.

• The reaction is carried out in the presence of a strong acid catalyst, such as sulfuric acid or hydrochloric acid.

• The oxime is first protonated by the acid catalyst, which then undergoes rearrangement to form an isocyanate intermediate.

• The isocyanate intermediate then reacts with water to form the desired amide product.

• Th...read more

MCPBA is a powerful oxidizing agent used in organic chemistry reactions.

• MCPBA stands for meta-chloroperoxybenzoic acid.

• It is commonly used to convert alkenes into epoxides.

• The mechanism involves the transfer of an oxygen atom from MCPBA to the double bond of the alkene, forming an epoxide.

• MCPBA can also oxidize sulfides to sulfoxides and sulfones.

• It is a versatile reagent in various oxidation reactions.

Suzuki coupling is a palladium-catalyzed cross-coupling reaction between organoboron compounds and organic halides.

• The reaction involves the oxidative addition of the organic halide to the palladium catalyst, followed by transmetalation with the organoboron compound.

• The resulting intermediate undergoes reductive elimination to form the coupled product.

• Suzuki coupling is widely used in organic synthesis to form carbon-c...read more