Govindraj Associates Interview Questions and Answers

Temperature affects the separation and retention time of analytes in HPLC analysis.

• Higher temperature can decrease retention time and resolution.

• Lower temperature can increase retention time and resolution.

• Temperature should be controlled and kept constant during analysis.

• Column temperature can affect the selectivity of the stationary phase.

• Temperature can also affect the viscosity of the mobile phase and the solubility of the analytes.

About refers to an approximate amount or quantity.

• About means approximately or roughly.

• It is used when an exact amount is not known or specified.

• For example, 'I need about 2 cups of flour for this recipe.'

Peak purity is a measure of the homogeneity of a chromatographic peak, indicating the presence of impurities or co-eluting compounds.

• Peak purity is determined by comparing the spectra of the peak at different wavelengths.

• A pure peak will have a consistent spectrum across different wavelengths, while impurities will show variations.

• Peak purity analysis is commonly used in pharmaceutical and analytical chemistry to ensure the quality and purity of drugs and compounds.

• It can be ...read more

Noise is unwanted or unpleasant sound that can cause disturbance or harm to human health.

• Noise can be caused by various sources such as traffic, construction, industrial machinery, and loud music.

• Exposure to high levels of noise can lead to hearing loss, stress, and other health problems.

• Noise pollution is a growing concern in urban areas and can have negative impacts on both humans and wildlife.

• Noise can be measured in decibels (dB) and the safe exposure limit for humans is ...read more

LOQ and LOD values are used in analytical chemistry to determine the lowest concentration of a substance that can be reliably detected and quantified.

• LOQ stands for Limit of Quantification and is the lowest concentration of a substance that can be reliably quantified.

• LOD stands for Limit of Detection and is the lowest concentration of a substance that can be reliably detected.

• LOD is usually higher than LOQ.

• LOQ and LOD are important parameters in analytical chemistry and are u...read more

21 CFR part 11 is a regulation by the FDA for electronic records and signatures. Data integrity refers to the accuracy and consistency of data. ALCOA stands for Attributable, Legible, Contemporaneous, Original, and Accurate. Cleaning validation is the process of ensuring that cleaning procedures effectively remove residues. Handling deviations involves documenting, investigating, and resolving any deviations from standard procedures. CAPA stands for Corrective and Preventive ...read more