10+ Senior Researcher Interview Questions and Answers

Method validation is the process of demonstrating that an analytical method is suitable for its intended use.

• Method validation ensures that the method is accurate, precise, specific, and robust.

• It involves evaluating various parameters such as linearity, accuracy, precision, specificity, limit of detection, limit of quantitation, and robustness.

• There are different types of method validation, including validation of analytical methods, bioanalytical methods, and microbiologica...read more

Neurogenerative disorders are conditions that cause progressive degeneration of the nervous system. Drugs used include dopamine agonists, cholinesterase inhibitors, and NMDA receptor antagonists.

• Neurogenerative disorders are characterized by the gradual loss of neurons in the brain and spinal cord.

• Common neurogenerative disorders include Alzheimer's disease, Parkinson's disease, and Huntington's disease.

• Drugs used to treat these disorders aim to alleviate symptoms and slow do...read more

Phase I studies focus on the safety and tolerability of a new drug in a small group of healthy volunteers.

• Phase I studies involve a small number of participants, usually healthy volunteers.

• The main goal is to determine the safety and tolerability of the drug at different doses.

• These studies also look at how the drug is metabolized and excreted in the body.

• Phase I studies are usually the first step in testing a new drug before moving on to larger trials.

• Examples of phase I stu...read more

Early phase I is the initial stage of clinical trials to test the safety and dosage of a new drug in a small group of healthy volunteers.

• Small group of healthy volunteers are given the drug

• Focus is on safety and dosage

• Usually involves fewer than 30 participants

• Helps determine if the drug is safe enough to move on to phase II

Literature gap refers to the missing or incomplete information in existing research or publications.

• Literature gap is the area where current research has not adequately addressed a particular topic or question.

• It highlights the need for further research to fill the gaps in knowledge.

• Identifying literature gaps is important for researchers to contribute new insights and advancements in their field.

• Examples of literature gaps include contradictory findings in existing studies, ...read more

Market capitalisation is the total value of a company's outstanding shares of stock, calculated by multiplying the current stock price by the total number of outstanding shares.

• Market capitalisation is used to determine the size of a company in the stock market.

• It is calculated by multiplying the current stock price by the total number of outstanding shares.

• Market capitalisation helps investors assess the value and risk of investing in a particular company.

• For example, if a c...read more

Adr vs Ae difference and definitions

• ADR stands for Adverse Drug Reaction, which refers to any harmful or unintended reaction to a medication at normal doses

• AE stands for Adverse Event, which is any untoward medical occurrence in a patient or clinical investigation subject

• The main difference is that ADR specifically refers to reactions caused by a drug, while AE is a broader term encompassing any negative medical event

• Examples of ADRs include nausea, rash, or dizziness due to ...read more

UX process involves understanding user needs, designing solutions, and testing them for usability.

• Research user needs and behaviors

• Create user personas and scenarios

• Design user interfaces and interactions

• Test and iterate on designs

• Implement and launch the final product

• Examples: user interviews, wireframing, prototyping, usability testing

Clinical trials typically consist of four phases: Phase 0, Phase I, Phase II, and Phase III.

• Phase 0: Exploratory study involving very limited human exposure to the drug.

• Phase I: Small group of healthy volunteers to determine safety and dosage.

• Phase II: Larger group to further evaluate safety and efficacy.

• Phase III: Large-scale study to confirm effectiveness, monitor side effects, and compare to existing treatments.

Classification of drugs involves categorizing them based on their pharmacological effects, chemical structure, and therapeutic use.

• Drugs can be classified based on their pharmacological effects such as analgesics, antibiotics, antihypertensives, etc.

• Classification can also be done based on chemical structure like opioids, benzodiazepines, steroids, etc.

• Therapeutic use classification includes categories like antidiabetics, antipsychotics, antihistamines, etc.

I am proficient in various programming languages such as Java, Python, and C++. I am also familiar with database management systems like MySQL and Oracle.

• Proficient in Java, Python, and C++

• Familiar with MySQL and Oracle

• Experience with software development and database management