Research Associate 1 Interview Questions and Answers

Chiral molecules have non-superimposable mirror images called enantiomers. Enantiomers have opposite configurations at all chiral centers.

• Chiral molecules are asymmetrical and have a mirror image that cannot be superimposed on the original molecule.

• Enantiomers are pairs of molecules that are mirror images of each other but not superimposable.

• Diastereomers are stereoisomers that are not mirror images of each other.

• The number of possible enantiomers for a compound is 2^n, where...read more

HPLC calibration and validation parameters

• HPLC calibration parameters include wavelength accuracy, flow rate accuracy, and retention time precision.

• Validation parameters include system suitability, linearity, accuracy, precision, and robustness.

• For example, wavelength accuracy is determined by analyzing a standard solution at different wavelengths and comparing the obtained results.

• System suitability is assessed by analyzing a standard solution and ensuring that the chromatog...read more

1HNMR values are important for characterizing lab synthesised compounds.

• 1HNMR spectroscopy is a powerful tool for determining the structure of organic compounds.

• The chemical shift of a proton in an NMR spectrum is affected by its chemical environment.

• The integration of the peaks in an NMR spectrum can provide information about the number of protons in a particular environment.

• The coupling of protons in an NMR spectrum can provide information about the connectivity of atoms in...read more

Named reactions in organic chemistry are specific chemical reactions that have been given a name for easy reference.

• Named reactions are often named after the chemist who discovered or developed them.

• They are commonly used in organic synthesis to create specific compounds.

• Examples include the Grignard reaction, the Friedel-Crafts reaction, and the Diels-Alder reaction.