20+ QC Analyst Interview Questions and Answers

The pH scale measures the acidity or basicity of a substance. It ranges from 0 to 14, with 7 being neutral.

• pH measures the concentration of hydrogen ions in a solution

• Acids have a pH less than 7, while bases have a pH greater than 7

• The molecular weight (MW) of a substance is the sum of the atomic weights of its atoms

• Density is the mass of a substance per unit volume

• Normality is a measure of concentration in chemical solutions

• Basic reactions involve the transfer of protons (H+...read more

UV range is 190-400 nm, common makes include Agilent and Shimadzu, principle is based on absorption of UV light. UV calibration involves using standard solutions and adjusting wavelength and absorbance.

• UV range typically falls between 190-400 nm

• Common makes of UV instruments include Agilent and Shimadzu

• Principle of UV analysis is based on the absorption of UV light by the sample

• UV calibration involves using standard solutions of known concentrations

• Calibration includes adjust...read more

Functional groups in IR spectroscopy can be identified by analyzing characteristic peaks in the spectrum and comparing them to reference data.

• Identify the presence of functional groups by looking for specific peaks in the IR spectrum

• Use reference tables or databases to match the observed peaks with known functional groups

• Look for characteristic peaks such as C=O stretch for carbonyl groups, O-H stretch for alcohols, and N-H stretch for amines

• Consider the intensity and positio...read more

KF Reagent solutions contain chemicals like methanol, sulfur dioxide, and iodine in specific ratios for accurate moisture determination.

• KF Reagent solutions typically contain methanol as a solvent

• Sulfur dioxide is added to prevent side reactions

• Iodine is the titrant used in the Karl Fischer titration method

• The chemicals in KF Reagent solutions are carefully balanced to ensure accurate moisture determination

DST is used to break down the sample matrix and release water for titration, while Methanol is used as a solvent for the sample.

• DST (Di Sodium Tartrate) is used to break down the sample matrix and release water molecules for titration.

• Methanol is used as a solvent to dissolve the sample and ensure accurate titration results.

• Both DST and Methanol help in ensuring precise and reliable Karl Fischer titration results.

Calibration of polarimeter is essential for accurate measurements. Sucrose is commonly used as it has a known specific rotation.

• Calibration of polarimeter involves adjusting the instrument to ensure accurate readings.

• Sucrose is often used for calibration as it has a well-known specific rotation value.

• By calibrating the polarimeter with sucrose, the instrument can accurately measure the specific rotation of other substances.

• Regular calibration ensures the reliability and accur...read more

I use a pH meter for testing and calibrate it regularly to ensure accurate results.

• I use a pH meter to measure the acidity or alkalinity of a solution.

• Calibration involves adjusting the pH meter to ensure accurate readings.

• I calibrate the pH meter using buffer solutions of known pH levels.

• Regular calibration is important to maintain the accuracy of the pH meter.

• Examples of buffer solutions used for calibration include pH 4.01, 7.00, and 10.01 solutions.

Muffler furnace is used for controlled heating and H2SO4 is used for acid digestion in analytical testing.

• Muffler furnace provides controlled heating for accurate analysis of samples

• H2SO4 is used for acid digestion to break down samples for analysis

• Both tools are essential for accurate and precise analytical testing

I have experience as a QC Analyst in the medical field.

• Worked as a QC Analyst for 3 years at XYZ Pharmaceuticals

• Performed analytical testing on pharmaceutical products

• Conducted quality control checks to ensure compliance with regulations

• Developed and validated analytical methods

• Prepared and reviewed documentation, including SOPs and test reports

Instruments are tools or devices used for measuring, analyzing, or controlling a process or system.

• Instruments can be used in various industries such as healthcare, manufacturing, and research.

• Examples of instruments include spectrophotometers, chromatographs, and pH meters.

• Instruments are calibrated regularly to ensure accuracy and reliability of measurements.

• Some instruments are automated, while others require manual operation.

• Proper maintenance and handling of instruments ...read more

QC stands for Quality Control, which is a process used to ensure that products meet specific quality standards.

• QC involves monitoring and testing products to ensure they meet quality standards

• It helps identify defects or deviations from specifications

• QC can involve sampling, testing, and inspection of products

• Examples include checking the dimensions of a manufactured part, testing the purity of a drug, or inspecting the packaging of a food product

There are several types of testing including functional, performance, security, usability, and more.

• Functional testing ensures that the software meets the specified requirements.

• Performance testing checks the system's ability to handle a large number of users or transactions.

• Security testing identifies vulnerabilities and ensures that the system is secure.

• Usability testing evaluates the user-friendliness of the software.

• Other types of testing include compatibility testing, re...read more

GMP stands for Good Manufacturing Practice.

• GMP is a set of guidelines that ensure products are consistently produced and controlled according to quality standards.

• It is important in industries such as pharmaceuticals, food, and cosmetics.

• Examples of GMP requirements include proper documentation, sanitation, and quality control measures.

SOP stands for Standard Operating Procedure.

• SOP is a set of step-by-step instructions compiled by an organization to help workers carry out routine operations.

• It ensures consistency and quality in the performance of tasks.

• Examples include SOPs for laboratory testing procedures, manufacturing processes, and safety protocols.

The mobile phase in process HPLC is a liquid or mixture of liquids that carries the sample through the column.

• The mobile phase is typically composed of a solvent or a combination of solvents.

• It should be compatible with the sample and the stationary phase in the column.

• The mobile phase should have appropriate polarity and viscosity for efficient separation.

• Common mobile phase solvents include water, methanol, acetonitrile, and tetrahydrofuran.

• The composition and ratio of the ...read more

Food safety management system ensures food products are safe for consumption by implementing procedures and controls.

• Establishing and maintaining a food safety plan based on HACCP principles

• Implementing Good Manufacturing Practices (GMP) to ensure safe food handling

• Conducting regular inspections and audits to identify and address potential hazards

• Training employees on food safety protocols and procedures

• Maintaining proper documentation of all food safety activities

HACCP (Hazard Analysis and Critical Control Points) is a systematic preventive approach to food safety that addresses physical, chemical, and biological hazards.

• Identify potential hazards in the food production process

• Determine critical control points where hazards can be prevented, eliminated, or reduced to safe levels

• Establish critical limits for each control point

• Monitor and maintain control of the critical control points

• Establish corrective actions to be taken when monito...read more