20+ QC Analyst Interview Questions and Answers

The pH scale measures the acidity or basicity of a substance. It ranges from 0 to 14, with 7 being neutral.

• pH measures the concentration of hydrogen ions in a solution

• Acids have a pH less than 7, while bases have a pH greater than 7

• The molecular weight (MW) of a substance is the sum of the atomic weights of its atoms

• Density is the mass of a substance per unit volume

• Normality is a measure of concentration in chemical solutions

• Basic reactions involve the transfer of protons (H+...read more

DST is used to break down the sample matrix and release water for titration, while Methanol is used as a solvent for the sample.

• DST (Di Sodium Tartrate) is used to break down the sample matrix and release water molecules for titration.

• Methanol is used as a solvent to dissolve the sample and ensure accurate titration results.

• Both DST and Methanol help in ensuring precise and reliable Karl Fischer titration results.

UV range is 190-400 nm, common makes include Agilent and Shimadzu, principle is based on absorption of UV light. UV calibration involves using standard solutions and adjusting wavelength and absorbance.

• UV range typically falls between 190-400 nm

• Common makes of UV instruments include Agilent and Shimadzu

• Principle of UV analysis is based on the absorption of UV light by the sample

• UV calibration involves using standard solutions of known concentrations

• Calibration includes adjust...read more

Functional groups in IR spectroscopy can be identified by analyzing characteristic peaks in the spectrum and comparing them to reference data.

• Identify the presence of functional groups by looking for specific peaks in the IR spectrum

• Use reference tables or databases to match the observed peaks with known functional groups

• Look for characteristic peaks such as C=O stretch for carbonyl groups, O-H stretch for alcohols, and N-H stretch for amines

• Consider the intensity and positio...read more

KF Reagent solutions contain chemicals like methanol, sulfur dioxide, and iodine in specific ratios for accurate moisture determination.

• KF Reagent solutions typically contain methanol as a solvent

• Sulfur dioxide is added to prevent side reactions

• Iodine is the titrant used in the Karl Fischer titration method

• The chemicals in KF Reagent solutions are carefully balanced to ensure accurate moisture determination

Chemistry is the study of matter and its properties. Inorganic chemistry deals with non-living matter while analytical chemistry focuses on the analysis of substances.

• Chemistry is the scientific study of matter, its properties, and how it interacts with other matter.

• Inorganic chemistry deals with the study of non-living matter such as minerals, metals, and chemicals.

• Analytical chemistry focuses on the analysis of substances to determine their composition, structure, and prope...read more

Calibration of polarimeter is essential for accurate measurements. Sucrose is commonly used as it has a known specific rotation.

• Calibration of polarimeter involves adjusting the instrument to ensure accurate readings.

• Sucrose is often used for calibration as it has a well-known specific rotation value.

• By calibrating the polarimeter with sucrose, the instrument can accurately measure the specific rotation of other substances.

• Regular calibration ensures the reliability and accur...read more

Muffler furnace is used for controlled heating and H2SO4 is used for acid digestion in analytical testing.

• Muffler furnace provides controlled heating for accurate analysis of samples

• H2SO4 is used for acid digestion to break down samples for analysis

• Both tools are essential for accurate and precise analytical testing

I have experience as a QC Analyst in the medical field.

• Worked as a QC Analyst for 3 years at XYZ Pharmaceuticals

• Performed analytical testing on pharmaceutical products

• Conducted quality control checks to ensure compliance with regulations

• Developed and validated analytical methods

• Prepared and reviewed documentation, including SOPs and test reports

Instruments are tools or devices used for measuring, analyzing, or controlling a process or system.

• Instruments can be used in various industries such as healthcare, manufacturing, and research.

• Examples of instruments include spectrophotometers, chromatographs, and pH meters.

• Instruments are calibrated regularly to ensure accuracy and reliability of measurements.

• Some instruments are automated, while others require manual operation.

• Proper maintenance and handling of instruments ...read more

Test cases should be written in a structured and organized manner to ensure comprehensive testing.

• Identify the requirements and objectives of the software

• Create a test plan outlining the scope and approach

• Write test cases that cover all possible scenarios and edge cases

• Ensure each test case is clear, concise, and unambiguous

• Include preconditions, steps, and expected results for each test case

• Execute the test cases and record the results

• Review and refine the test cases as nece...read more

Ch3COOH, or acetic acid, is a weak acid that partially dissociates in water, making it less potent than strong acids.

• Acetic acid (CH3COOH) is commonly found in vinegar.

• Weak acids like acetic acid only partially ionize in solution.

• In contrast, strong acids like hydrochloric acid (HCl) fully dissociate in water.

• The pH of a weak acid solution is higher than that of a strong acid at the same concentration.

Formic acid is a weak acid, partially dissociating in solution, making it less potent than strong acids like hydrochloric acid.

• Formic acid (HCOOH) has a pKa of about 3.75, indicating it is a weak acid.

• Weak acids only partially ionize in solution; for example, acetic acid is another weak acid.

• In contrast, strong acids like sulfuric acid fully dissociate in water.

Phenol is considered a weak acid due to its limited dissociation in water compared to strong acids.

• Phenol (C6H5OH) partially dissociates in water, releasing H+ ions.

• Its pKa value is around 10, indicating it is weaker than strong acids like HCl (pKa ≈ -7).

• In comparison, acetic acid (CH3COOH) is also a weak acid with a pKa of about 4.76.

• Phenol can act as both an acid and a base, showcasing amphoteric properties.

GMP stands for Good Manufacturing Practice.

• GMP is a set of guidelines that ensure products are consistently produced and controlled according to quality standards.

• It is important in industries such as pharmaceuticals, food, and cosmetics.

• Examples of GMP requirements include proper documentation, sanitation, and quality control measures.

There are several types of testing including functional, performance, security, usability, and more.

• Functional testing ensures that the software meets the specified requirements.

• Performance testing checks the system's ability to handle a large number of users or transactions.

• Security testing identifies vulnerabilities and ensures that the system is secure.

• Usability testing evaluates the user-friendliness of the software.

• Other types of testing include compatibility testing, re...read more

SOP stands for Standard Operating Procedure.

• SOP is a set of step-by-step instructions compiled by an organization to help workers carry out routine operations.

• It ensures consistency and quality in the performance of tasks.

• Examples include SOPs for laboratory testing procedures, manufacturing processes, and safety protocols.

I am a dedicated QC Analyst with a strong background in quality control processes and a passion for ensuring product excellence.

• Over 5 years of experience in quality control in the manufacturing sector.

• Skilled in using various testing methodologies, such as statistical sampling.

• Proficient in tools like Six Sigma and Lean methodologies to improve processes.

• Experience in conducting audits and inspections to ensure compliance with standards.

• Strong analytical skills, demonstrated...read more

NaOH, or sodium hydroxide, is classified as a strong base due to its complete dissociation in water.

• NaOH dissociates completely in water, releasing OH- ions.

• Strong bases have a high pH, typically above 12.

• Examples of strong bases include NaOH, KOH, and Ca(OH)2.

• Weak bases, like ammonia (NH3), do not fully dissociate in solution.

The mobile phase in process HPLC is a liquid or mixture of liquids that carries the sample through the column.

• The mobile phase is typically composed of a solvent or a combination of solvents.

• It should be compatible with the sample and the stationary phase in the column.

• The mobile phase should have appropriate polarity and viscosity for efficient separation.

• Common mobile phase solvents include water, methanol, acetonitrile, and tetrahydrofuran.

• The composition and ratio of the ...read more

H2SO4, or sulfuric acid, is a strong acid that completely dissociates in water, making it highly reactive and corrosive.

• H2SO4 dissociates completely in aqueous solution, releasing H+ ions.

• It is used in various industrial processes, such as fertilizer production.

• Sulfuric acid is a key component in lead-acid batteries.

• It can cause severe burns and is highly corrosive to metals.

Food safety management system ensures food products are safe for consumption by implementing procedures and controls.

• Establishing and maintaining a food safety plan based on HACCP principles

• Implementing Good Manufacturing Practices (GMP) to ensure safe food handling

• Conducting regular inspections and audits to identify and address potential hazards

• Training employees on food safety protocols and procedures

• Maintaining proper documentation of all food safety activities

HACCP (Hazard Analysis and Critical Control Points) is a systematic preventive approach to food safety that addresses physical, chemical, and biological hazards.

• Identify potential hazards in the food production process

• Determine critical control points where hazards can be prevented, eliminated, or reduced to safe levels

• Establish critical limits for each control point

• Monitor and maintain control of the critical control points

• Establish corrective actions to be taken when monito...read more