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I applied via Referral and was interviewed in Jul 2022. There were 3 interview rounds.
Versant test was conducted
I applied via Referral and was interviewed in Nov 2021. There were 2 interview rounds.
Method development of HPLC and Prep-HPLC involves optimizing parameters for separation and purification of compounds.
Determine the appropriate stationary phase and mobile phase for the separation
Optimize flow rate, column temperature, and gradient conditions
Use appropriate detection methods such as UV or MS
For Prep-HPLC, scale up the method and adjust parameters for larger column sizes
Validate the method for accuracy,
I applied via Recruitment Consulltant and was interviewed before Aug 2022. There were 2 interview rounds.
The NMR peak of ethyl acetate typically appears around 1.2-2.0 ppm.
The NMR peak of ethyl acetate is usually observed as a singlet around 1.2-2.0 ppm.
The peak may shift slightly depending on the solvent used for the NMR analysis.
The chemical structure of ethyl acetate consists of an ethyl group and an acetate group, which contribute to the NMR peak.
The peak intensity and splitting pattern can provide additional informat
Pd coupling reactions involve the cross-coupling of two different carbon atoms using palladium as a catalyst.
Pd coupling reactions are widely used in organic synthesis to form carbon-carbon bonds.
Examples include Suzuki coupling, Sonogashira coupling, Heck reaction, and Stille coupling.
These reactions typically involve a palladium catalyst, a base, and appropriate coupling partners.
Suzuki coupling involves the reaction...
I applied via Company Website and was interviewed before May 2021. There were 4 interview rounds.
Syngene International interview questions for designations
I applied via Company Website and was interviewed in May 2021. There were 3 interview rounds.
Selective reduction of acid in presence of ester
Use a reducing agent that selectively reduces acid over ester
Common reducing agents are LiAlH4 and NaBH4
LiAlH4 reduces both acid and ester, but in presence of acid it selectively reduces acid
NaBH4 reduces only acid, not ester
Example: Reduction of benzoic acid to benzyl alcohol in presence of benzyl ester using LiAlH4
Get interview-ready with Top Syngene International Interview Questions
I applied via Referral and was interviewed in May 2021. There were 3 interview rounds.
Interpretation of NMR with coupling constant
Coupling constant is the distance between two peaks in a multiplet
It indicates the number of neighboring protons
The coupling constant can be used to determine the stereochemistry of a molecule
The coupling constant can also be used to determine the hybridization of a carbon atom
The magnitude of the coupling constant depends on the strength of the spin-spin coupling
A doublet ha...
The molecule can be converted into another molecule using reducing or oxidizing agents.
Identify the functional groups present in the molecule
Choose a suitable reducing or oxidizing agent based on the functional groups
Perform the reaction under appropriate conditions
Isolate and purify the product
Examples: converting a ketone to an alcohol using NaBH4 as a reducing agent, converting an alcohol to a ketone using PCC as an
I applied via Recruitment Consultant and was interviewed in Dec 2020. There were 4 interview rounds.
BuLi reagent is a highly reactive and pyrophoric compound used in organic synthesis.
BuLi should be handled under an inert atmosphere, such as nitrogen or argon.
It should be stored in a dry and cool place, away from water and air.
BuLi should be added slowly to the reaction mixture, with constant stirring.
Personal protective equipment, such as gloves and goggles, should be worn at all times.
In case of fire, use a Class D...
Reagents used in Suzuki coupling
Palladium catalyst (e.g. Pd(PPh3)4)
Organoboron compound (e.g. arylboronic acid)
Base (e.g. potassium carbonate)
Solvent (e.g. DMF, toluene)
Rest ethyl acetate in compound can be found by NMR using specific peaks and chemical shifts.
Look for the peak at 1.0-1.2 ppm which corresponds to the ethyl group
Look for the peak at 4.0-4.1 ppm which corresponds to the acetate group
Subtract the integral of these peaks from the total integral to find the rest ethyl acetate
Compare the chemical shifts of the peaks to known values for ethyl acetate
I applied via LinkedIn and was interviewed before Nov 2021. There were 2 interview rounds.
I applied via Naukri.com and was interviewed before Jun 2020. There were 3 interview rounds.
I applied via Company Website and was interviewed before May 2020. There were 6 interview rounds.
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