Raptim Research QC Chemist Interview Questions and Answers

Q1. Define Suzuki coupling reaction
Ans. 
Suzuki coupling reaction is a cross-coupling reaction between an organoboron compound and an organic halide catalyzed by a palladium catalyst.
• Involves the coupling of an organoboron compound with an organic halide

• Catalyzed by a palladium catalyst

• Forms a new carbon-carbon bond

• Widely used in organic synthesis

• Example: Coupling of phenylboronic acid with bromobenzene
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Q2. NMR chemical shift values
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NMR chemical shift values are unique for each type of atom in a molecule and are influenced by surrounding chemical environment.
• Chemical shift values are measured in parts per million (ppm) relative to a standard reference compound.

• Different types of atoms (e.g. hydrogen, carbon) have characteristic chemical shift ranges.

• Chemical shift values can be influenced by factors such as neighboring atoms, functional groups, an
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Q1. All technical questions related to QC
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Q2. Gc principle and analysis.
Ans. 
Gas chromatography (GC) is a technique used to separate and analyze compounds in a mixture based on their volatility.
• GC relies on the principle of separating compounds based on their partitioning between a stationary phase and a mobile phase.

• Compounds with higher volatility will travel through the column faster and be detected earlier.

• GC is commonly used in the analysis of organic compounds, such as in drug testing or ...read more
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Q3. Column selection
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Discussion with Quality head

My interview conducted on vertual mode

Q1. Oxidation reduction base
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Q2. Function group interconversion
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Q3. Spectroscopy NMR IR most of q
Ans. 
Spectroscopy techniques NMR and IR are commonly used in chemistry research and analysis.
• NMR (nuclear magnetic resonance) spectroscopy is used to determine the structure and composition of molecules by analyzing their magnetic properties.

• IR (infrared) spectroscopy is used to identify functional groups in molecules by analyzing their absorption of infrared radiation.

• Both techniques are non-destructive and can be used to ...read more
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Chemical questions, structure, definition

Q1. Our details,hobbies, our confidence
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Written exam of subject

Q1. Reactions , NMR, purification techniques,
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Q2. Griganrd reaction, reducing agents ,
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Q1. Personal interview
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Q2. Self introduction
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Q3. Which section you have work
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Q4. How many sample analysed per day
Ans. 
The number of samples analyzed per day varies depending on the workload and complexity of the samples.
• The number of samples analyzed per day can range from 50 to 200, depending on the size of the laboratory and the efficiency of the processes.

• Factors such as the type of analysis required, equipment availability, and staff expertise can also impact the number of samples analyzed per day.

• For example, in a high-throughput...read more
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Q1. What is the role of died mitsnubu reaction?
Ans. 
The Dieckmann condensation or Dieckmann cyclization is a chemical reaction used to form a cyclic molecule from a diester.
• The reaction involves the formation of a cyclic molecule from a diester through intramolecular nucleophilic substitution.

• It is named after German chemist Walter Dieckmann.

• The reaction is commonly used in the synthesis of cyclic ketones and lactones.

• The reaction can be catalyzed by both acids and base...read more
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Q2. What is Buchwald coupling
Ans. 
Buchwald coupling is a palladium-catalyzed cross-coupling reaction used to form carbon-carbon bonds.
• Buchwald coupling is a type of cross-coupling reaction in organic chemistry.

• It involves the use of a palladium catalyst to form carbon-carbon bonds.

• The reaction typically involves an aryl halide or pseudohalide and an organoboron compound as reactants.

• Buchwald coupling is widely used in the synthesis of pharmaceuticals, ...read more
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Q1. All named reactions,pyrophobic chemicals, oxidation reactions, reduction reactions
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