Biocon Biologics Associate Manager Interview Questions and Answers

5 codes(easy to moderate difficulty)

Q1. SQL, some simple codes, aptitude database related questions
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Q1. Pattern printing, SQL
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Q1. Conversation reaction
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Q1. Downstream operations
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Q2. Calculate the coloumn volume
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Column volume can be calculated by multiplying the cross-sectional area of the column by its height.
• Calculate the cross-sectional area of the column (e.g. if the column is cylindrical, use the formula A = πr^2)

• Measure the height of the column

• Multiply the cross-sectional area by the height to get the column volume
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Q1. Intro abt ourselves
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Q2. Knowledge in Company what they are doing
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Q1. How to handle and quench pyrophoric chemical in reaction.
Ans. 
Pyrophoric chemicals can be handled and quenched by using inert gases, specialized containers, and proper disposal methods.
• Use inert gases such as nitrogen or argon to displace air and prevent ignition.

• Store and handle pyrophoric chemicals in specialized containers such as air-tight glass ampoules or sealed metal containers.

• Dispose of pyrophoric chemicals properly by contacting a hazardous waste disposal company.

• Exampl...read more
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Q2. Name reactions based on palladium chemistry and copper chemistry
Ans. 
Palladium and copper chemistry are widely used in organic synthesis. Some important reactions include Suzuki coupling, Heck reaction, Sonogashira coupling, and Ullmann reaction.
• Suzuki coupling: cross-coupling reaction between an organoboron compound and an organic halide or triflate catalyzed by a palladium complex

• Heck reaction: coupling of an aryl or vinyl halide with an alkene in the presence of a palladium catalyst

• S...read more
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Q3. Different oxidising and reducing agent for ester reduction,cyano reduction, alchol oxidation
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Different oxidising and reducing agents used for ester reduction, cyano reduction, and alcohol oxidation.
• Ester reduction: Lithium aluminum hydride (LiAlH4), sodium borohydride (NaBH4), diisobutylaluminum hydride (DIBAL-H)

• Cyano reduction: Lithium aluminum hydride (LiAlH4), sodium borohydride (NaBH4)

• Alcohol oxidation: Chromium trioxide (CrO3), potassium permanganate (KMnO4), Jones reagent (CrO3/H2SO4)
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Q4. Indole, oxazole and isoxazole synthesis route
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Q1. Analytical instruments
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Q2. Chemistry of indicator
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Indicators are substances that change color in response to changes in pH levels, helping to determine the acidity or alkalinity of a solution.
• Indicators are typically weak acids or bases that dissociate in water and change color based on the concentration of H+ ions.

• Common indicators include phenolphthalein, litmus, and bromothymol blue.

• The color change of an indicator is due to a shift in the equilibrium between the a...read more
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