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Y-Axis Overseas Careers Interview Questions and Answers

Updated 5 Feb 2024
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Q1. What's S1, S2 and S3 in dissolution?

Ans.

S1, S2, and S3 in dissolution refer to the stages of dissolution testing in pharmaceutical analysis.

  • S1 is the stage where the tablet starts to disintegrate into smaller particles.

  • S2 is the stage where the drug starts to dissolve into the surrounding medium.

  • S3 is the stage where the drug is completely dissolved and available for absorption.

  • These stages are important in determining the release rate of the drug from the dosage form.

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Q2. What's Q stands for in Dissolution?

Ans.

Q stands for Quantity in Dissolution.

  • Q stands for Quantity in Dissolution testing.

  • It refers to the amount of drug substance that is dissolved in a specified time period.

  • It is an important parameter in assessing the quality and performance of a drug product.

  • Q can also stand for Quality in some contexts, but in Dissolution it specifically refers to Quantity.

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Q3. What's Normality, Molarity and Molality?

Ans.

Normality, Molarity, and Molality are different units of concentration used in chemistry.

  • Normality is the number of equivalents of a substance dissolved in a liter of solution.

  • Molarity is the number of moles of solute per liter of solution.

  • Molality is the number of moles of solute per kilogram of solvent.

  • Normality is used in acid-base reactions, while Molarity and Molality are more commonly used in general chemistry.

  • Example: A 1M solution of NaCl has 1 mole of NaCl dissolved ...read more

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Q4. What is UV and Visible Range?

Ans.

UV and visible range refer to the wavelengths of electromagnetic radiation that are visible to the human eye.

  • UV range typically refers to wavelengths between 10-400 nm, while visible range refers to wavelengths between 400-700 nm.

  • UV radiation is divided into UVA (315-400 nm), UVB (280-315 nm), and UVC (100-280 nm).

  • Visible light is the portion of the electromagnetic spectrum that is visible to the human eye and includes colors from violet to red.

  • UV and visible range are common...read more

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Q5. What's principal of HPLC

Ans.

HPLC stands for High Performance Liquid Chromatography, a technique used to separate, identify, and quantify components in a mixture.

  • HPLC involves a stationary phase, a mobile phase, and a detector.

  • The sample is injected into the system and carried by the mobile phase through the stationary phase.

  • Different components in the sample interact differently with the stationary phase, leading to separation.

  • The detector measures the amount of each component as it elutes from the colu...read more

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Q6. What's Dissolution stages

Ans.

Dissolution stages refer to the different phases in which a solid substance dissolves in a liquid medium.

  • Dissolution begins with the solid substance breaking down into smaller particles

  • The smaller particles then disperse in the liquid medium

  • Finally, the particles fully dissolve and become uniformly distributed in the liquid

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Q7. What's ALCOA+++?

Ans.

ALCOA+++ is a set of principles for data integrity in the pharmaceutical industry.

  • Attributable

  • Legible

  • Contemporaneous

  • Original

  • Accurate

  • Complete

  • Consistent

  • Enduring

  • Available

  • Traceable

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Q8. What's OOS and OOT?

Ans.

OOS stands for Out of Specification and OOT stands for Out of Trend.

  • OOS refers to a result that falls outside the acceptance criteria specified in the test procedure.

  • OOT refers to a result that shows a trend outside the expected range over time.

  • Both OOS and OOT results may indicate potential issues with the quality or consistency of the product being tested.

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