Senior Project Fellow Interview Questions and Answers

Tools like Primer3, BLAST, and SSRFinder are used to design microsatellite markers using genome and transcriptome data.

• Primer3 is used to design PCR primers for amplifying microsatellite regions

• BLAST is used to search for homologous sequences in the genome or transcriptome data

• SSRFinder is used to identify potential microsatellite regions in the sequences

• Other tools like MISA and QDD may also be used for microsatellite marker design

Bioinformatics tools are used to assess population genetic structure by analyzing genetic data from different populations.

• Population structure analysis tools include STRUCTURE, ADMIXTURE, and PCA

• These tools help identify genetic clusters, admixture, and relatedness among individuals

• They are used to study evolutionary relationships, migration patterns, and genetic diversity within populations

Bulk Segregation Analysis is a method used to identify genetic markers linked to a specific trait by analyzing the segregation of markers in a population.

• BSA involves pooling DNA samples from individuals with the trait of interest and comparing them to individuals without the trait.

• Microsatellite markers are used to genotype the pooled DNA samples and identify regions of the genome that are linked to the trait.

• By analyzing the segregation of markers in the pooled samples, res...read more