Production Chemist

100+ Production Chemist Interview Questions and Answers

Updated 9 Jan 2025

Q51. Production of chlorinated plasticizer

Ans.

Chlorinated plasticizer is produced by reacting plasticizer with chlorine gas.

  • Chlorinated plasticizers are used as flame retardants in plastics.

  • The reaction is typically carried out in a batch reactor.

  • The process requires careful control of temperature and pressure.

  • The final product must be purified to remove any impurities.

  • Chlorinated plasticizers can be harmful to human health and the environment.

Q52. What is clean room

Ans.

A clean room is a controlled environment with low levels of pollutants such as dust, airborne microbes, aerosol particles, and chemical vapors.

  • Clean rooms are typically used in industries such as pharmaceuticals, biotechnology, electronics, and aerospace.

  • They are designed to maintain a specific level of cleanliness to ensure the quality of products being manufactured.

  • Clean rooms have strict protocols for entry, including wearing special clothing like gowns, gloves, masks, and...read more

Q53. What is API and how many type?

Ans.

API stands for Active Pharmaceutical Ingredient. There are two types of API - synthetic and natural.

  • API is the main active ingredient in a drug that produces the intended therapeutic effect.

  • Synthetic APIs are chemically synthesized in a laboratory.

  • Natural APIs are derived from natural sources such as plants, animals, or microorganisms.

  • APIs must meet strict quality standards and regulations before they can be used in pharmaceutical products.

Q54. What is the full form of PH

Ans.

PH stands for potential of hydrogen, a measure of the acidity or basicity of a solution.

  • PH stands for potential of hydrogen

  • It is a measure of the acidity or basicity of a solution

  • PH scale ranges from 0 (most acidic) to 14 (most basic)

  • Neutral PH is 7

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Q55. What is the valency of carbon

Ans.

The valency of carbon is 4.

  • Carbon typically forms 4 covalent bonds due to having 4 valence electrons.

  • This allows carbon to form a wide variety of compounds, including organic molecules.

  • Examples of carbon compounds include methane (CH4) and ethylene (C2H4).

Q56. Process of Autoclave.

Ans.

An autoclave is a device used to sterilize equipment and supplies by subjecting them to high-pressure steam.

  • Autoclave uses high-pressure steam to kill microorganisms and spores.

  • The process involves loading the items to be sterilized, adding water to the autoclave chamber, and sealing it.

  • The autoclave is then heated to a specific temperature and pressure for a set period of time.

  • After sterilization, the autoclave is depressurized and the items can be safely removed.

  • Autoclaves ...read more

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Q57. Which equipment handle?

Ans.

Production chemists handle a variety of equipment used in the manufacturing process.

  • Reactors

  • Centrifuges

  • Distillation columns

  • Mixers

  • Filtration systems

Q58. What is benzene.

Ans.

Benzene is a colorless, highly flammable liquid with a sweet odor. It is a basic building block of many chemicals.

  • Benzene is a hydrocarbon with the chemical formula C6H6.

  • It is a natural constituent of crude oil and gasoline.

  • Benzene is used in the production of plastics, synthetic fibers, rubber, dyes, detergents, and pharmaceuticals.

  • Exposure to benzene can cause cancer and other health problems.

  • Benzene is also a major air pollutant and is regulated by environmental agencies.

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Q59. What is your aim ?

Ans.

My aim is to utilize my skills and knowledge to contribute to the production process and ensure high-quality products are delivered efficiently.

  • To optimize production processes and increase efficiency

  • To ensure high-quality products are delivered to customers

  • To continuously improve and learn new skills to enhance production processes

  • To work collaboratively with team members to achieve production goals

Q60. What was organichemistry

Ans.

Organic chemistry is the study of carbon-based compounds and their properties, reactions, and synthesis.

  • It is a branch of chemistry that deals with the structure, properties, and reactions of organic compounds.

  • Organic compounds are molecules that contain carbon atoms bonded to hydrogen atoms and other elements such as oxygen, nitrogen, sulfur, and halogens.

  • Organic chemistry has many applications in fields such as medicine, agriculture, materials science, and energy production...read more

Q61. How many equipment handled

Ans.

I have experience handling a wide range of equipment in the production process.

  • I have experience handling various types of reactors, distillation columns, pumps, and filtration systems.

  • I am proficient in operating analytical instruments such as spectrophotometers, chromatographs, and titrators.

  • I have worked with process control systems like SCADA and PLCs to monitor and control production processes.

Q62. Types of pharma productions equipments

Ans.

Pharma production equipments include mixers, reactors, centrifuges, dryers, and filling machines.

  • Mixers are used to blend ingredients together

  • Reactors are used for chemical reactions

  • Centrifuges are used to separate solids from liquids

  • Dryers are used to remove moisture from products

  • Filling machines are used to package products into containers

  • Examples include ribbon blenders, jacketed reactors, basket centrifuges, fluid bed dryers, and automatic filling machines

Q63. What is a organic chemistry

Ans.

Organic chemistry is the branch of chemistry that deals with the study of carbon-containing compounds.

  • Organic chemistry focuses on the structure, properties, and reactions of carbon-based compounds.

  • It is a key discipline in the production of pharmaceuticals, plastics, fuels, and many other products.

  • Examples of organic compounds include ethanol, glucose, and aspirin.

Q64. How many types of table.

Ans.

The question is not relevant to the job of a production chemist.

  • This question is not related to the job of a production chemist.

  • It is important to stay focused on the job requirements during an interview.

  • If asked an irrelevant question, politely redirect the conversation back to the job requirements.

Q65. Why you joint pharma compny?

Ans.

I joined the pharma company because of my passion for chemistry and desire to contribute to the development of life-saving medications.

  • Passion for chemistry and pharmaceuticals

  • Desire to contribute to the development of life-saving medications

  • Opportunity to work in a dynamic and innovative industry

Q66. What are the tablet ?

Ans.

Tablets are solid dosage forms that contain medicinal substances and are intended for oral administration.

  • Tablets are one of the most common forms of medication.

  • They are made by compressing powdered or granulated drugs with excipients.

  • Tablets can vary in size, shape, color, and texture.

  • They are designed to be swallowed and dissolve in the gastrointestinal tract.

  • Tablets can be immediate-release, extended-release, or enteric-coated.

  • Examples of tablets include aspirin, paracetam...read more

Q67. What is tablet and tablet type

Ans.

A tablet is a solid dosage form containing active pharmaceutical ingredients and excipients compressed into a small, round, or oval shape.

  • Tablets are one of the most common forms of oral medication.

  • Tablets can be classified into different types based on their formulation, such as immediate-release, extended-release, chewable, effervescent, etc.

  • Examples of tablet types include aspirin tablets, ibuprofen tablets, and multivitamin tablets.

Q68. Moisture percentage of grade

Ans.

Moisture percentage is a critical parameter for determining the quality of a grade.

  • Moisture percentage is the amount of water present in a substance expressed as a percentage of the total weight.

  • It is important to control moisture levels in production to ensure product quality and stability.

  • Moisture content can affect the physical and chemical properties of a substance, such as its solubility, viscosity, and shelf life.

  • For example, a pharmaceutical grade may have a maximum mo...read more

Q69. Types of safety, and technical

Ans.

There are various types of safety and technical measures that a production chemist must be aware of.

  • Personal protective equipment (PPE) such as gloves, goggles, and lab coats

  • Chemical storage and handling procedures

  • Emergency response protocols

  • Equipment maintenance and calibration

  • Quality control measures

  • Documentation and record-keeping

  • Training and education for employees

  • Environmental safety measures

  • Fire safety measures

  • Electrical safety measures

Q70. What is type of distillation

Ans.

Distillation is a process used to separate components of a liquid mixture based on differences in boiling points.

  • Distillation involves heating a liquid mixture to create vapor, then cooling the vapor to condense it back into liquid form.

  • The components with lower boiling points will vaporize first and be collected, while the components with higher boiling points will remain in the original liquid.

  • Types of distillation include simple distillation, fractional distillation, and s...read more

Q71. How many classes in safety

Ans.

There are several classes in safety, including general safety, chemical safety, fire safety, electrical safety, and more.

  • General safety covers basic safety practices and procedures for all employees.

  • Chemical safety focuses on handling, storing, and disposing of hazardous chemicals.

  • Fire safety includes fire prevention, evacuation procedures, and proper use of fire extinguishers.

  • Electrical safety involves safe practices when working with electricity to prevent shocks and fires....read more

Q72. Technical parameters for formulation

Ans.

Technical parameters for formulation include raw materials, equipment, process parameters, and quality control measures.

  • Raw materials should be of high quality and meet specifications

  • Equipment should be calibrated and maintained regularly

  • Process parameters such as temperature, pressure, and mixing time should be optimized

  • Quality control measures should be in place to ensure consistency and purity of the final product

  • Examples of technical parameters include particle size distr...read more

Q73. How centrifuge pump work

Ans.

Centrifuge pumps work by using centrifugal force to move fluids through the pump.

  • Centrifuge pumps use a rotating impeller to create centrifugal force, which pushes the fluid towards the outlet.

  • The fluid enters the pump through the suction port and is accelerated by the impeller.

  • As the fluid moves through the pump, the centrifugal force increases its velocity and pressure, allowing it to be discharged through the outlet.

  • Centrifuge pumps are commonly used in industrial applicat...read more

Q74. What is frability?

Ans.

Frability is the tendency of a material to break or crumble easily.

  • Frability is a measure of the strength of a material.

  • It is often used to describe the quality of tablets or capsules.

  • A material with high frability will break or crumble easily, while a material with low frability will be more resistant to breaking.

  • Factors that can affect frability include the composition of the material, the manufacturing process, and the storage conditions.

  • Frability testing is an important p...read more

Q75. What is meadia fill ?

Ans.

Media fill is a simulation test used to evaluate the aseptic manufacturing process by filling sterile media instead of actual product.

  • Media fill is a validation test performed in pharmaceutical manufacturing.

  • It involves filling sterile growth media into containers and simulating the manufacturing process without actual product.

  • The purpose is to assess the aseptic techniques and procedures to ensure they are effective in preventing contamination.

  • Media fill tests are required b...read more

Q76. What is API in pharmacy

Ans.

API stands for Active Pharmaceutical Ingredient, which is the biologically active component in a pharmaceutical drug.

  • API is the main ingredient in a drug that produces the intended effect on the body.

  • It is responsible for the therapeutic effects of the drug.

  • Examples of APIs include paracetamol in painkillers and ibuprofen in anti-inflammatory drugs.

Q77. Temp of chlorine

Ans.

The temperature of chlorine depends on its state - gas, liquid or solid.

  • Chlorine gas has a boiling point of -34°C and a melting point of -101°C

  • Chlorine liquid has a boiling point of -34°C and a freezing point of -101°C

  • Chlorine solid has a melting point of -100.98°C

Q78. What is Hardness of tab.

Ans.

Hardness of a tablet refers to its ability to withstand pressure and not break or crumble easily.

  • Hardness is an important parameter in tablet manufacturing as it affects the tablet's disintegration and dissolution rates.

  • It is typically measured using a hardness tester which applies force to the tablet until it breaks.

  • Common units of measurement for tablet hardness include kg/cm^2 or N.

  • Hardness can vary depending on the formulation of the tablet and the manufacturing process u...read more

Q79. Any operation with safety

Ans.

Safety is a top priority in all operations to prevent accidents and injuries.

  • Always wear appropriate personal protective equipment (PPE)

  • Follow standard operating procedures (SOPs) for handling chemicals

  • Regularly inspect and maintain equipment to ensure safe operation

  • Participate in safety training and drills to be prepared for emergencies

Q80. What is tablet defect

Ans.

Tablet defect refers to any imperfection or flaw in a tablet that may affect its quality or performance.

  • Tablet defects can include cracks, chips, discoloration, capping, sticking, and hardness variations.

  • These defects can be caused by issues during the manufacturing process such as improper compression, inadequate drying, or contamination.

  • Examples of tablet defects include air pockets in the tablet, rough edges, and improper weight variation.

  • Inspecting tablets for defects is ...read more

Q81. What is molarity

Ans.

Molarity is a measure of the concentration of a solution expressed as the number of moles of solute per liter of solution.

  • Molarity is calculated by dividing the number of moles of solute by the volume of the solution in liters.

  • It is denoted by the symbol 'M'.

  • Molarity is commonly used in chemistry to express the concentration of a solution.

  • For example, a 1 M solution of sodium chloride contains 1 mole of sodium chloride per liter of solution.

Q82. Working principle of granulation

Ans.

Granulation is a process of forming agglomerates from fine powders by adding a binding agent and then drying.

  • Granulation involves mixing powders with a binding agent to form granules

  • The granules are then dried to remove moisture and solidify the structure

  • Common binding agents include water, alcohol, or polymers

  • Granulation improves flow properties, reduces dust, and enhances compressibility

  • Examples include pharmaceutical tablets, fertilizer granules, and detergent powders

Q83. Unit operations and transport phenomena

Ans.

Unit operations and transport phenomena are essential concepts in chemical engineering, involving processes like distillation, filtration, and heat transfer.

  • Unit operations refer to individual processes in chemical engineering, such as distillation, filtration, and crystallization.

  • Transport phenomena involve the movement of mass, energy, and momentum in chemical processes.

  • Examples of transport phenomena include heat transfer, mass transfer, and fluid flow.

  • Understanding unit o...read more

Q84. What is production

Ans.

Production is the process of creating goods or services using resources and labor.

  • Production involves converting raw materials into finished products.

  • It includes planning, scheduling, and managing resources to meet production goals.

  • Quality control is an important aspect of production to ensure the final product meets standards.

  • Examples of production include manufacturing cars, baking bread, and producing software.

  • Efficient production can lead to cost savings and increased pro...read more

Q85. Define pH and it's characteristics

Ans.

pH is a measure of acidity or alkalinity of a solution on a scale of 0-14, with 7 being neutral.

  • pH stands for 'potential of Hydrogen'

  • It is a logarithmic scale, meaning each whole pH value below 7 is 10 times more acidic than the next higher value, and each whole pH value above 7 is 10 times more alkaline than the next lower value

  • Acidic solutions have pH values below 7, while alkaline solutions have pH values above 7

  • Pure water has a pH of 7, which is considered neutral

  • Examples...read more

Q86. What is different dosage forms

Ans.

Different dosage forms refer to various ways in which medications can be administered to patients.

  • Dosage forms include tablets, capsules, syrups, injections, creams, ointments, and patches.

  • Each dosage form has its own advantages and disadvantages in terms of absorption rate, convenience, and patient compliance.

  • The choice of dosage form depends on the specific medication, patient preferences, and the condition being treated.

Q87. Pressure of chlorine

Ans.

The pressure of chlorine depends on its temperature and volume.

  • Chlorine gas is typically stored in pressurized cylinders.

  • The pressure of chlorine can be measured using a pressure gauge.

  • At room temperature, the pressure of chlorine in a cylinder is typically around 100 psi.

  • As the temperature of chlorine increases, its pressure also increases.

  • The pressure of chlorine can be calculated using the ideal gas law: PV = nRT.

Q88. Testing of grade

Ans.

Testing of grade is crucial to ensure quality and consistency of the product.

  • Testing involves analyzing the physical and chemical properties of the product.

  • Grade testing is done to ensure that the product meets the required specifications.

  • Testing can be done through various methods such as chromatography, spectroscopy, and titration.

  • Results of testing are compared to the standard specifications to determine if the product is acceptable.

  • Testing is done at various stages of pro...read more

Q89. What std in chemist

Ans.

Standard in chemistry refers to a reference material or method used for comparison and validation of experimental results.

  • Standards are used to ensure accuracy and precision in chemical measurements.

  • Examples of standards include NIST (National Institute of Standards and Technology) certified reference materials and ASTM (American Society for Testing and Materials) methods.

  • Standards can also refer to safety protocols and regulations in the handling and disposal of chemicals.

  • Ad...read more

Q90. What is granulation?

Ans.

Granulation is a process of forming grains or granules from a powdery substance.

  • Granulation involves the agglomeration of particles to form larger granules.

  • It is commonly used in pharmaceutical manufacturing to improve flow properties and reduce dust generation.

  • There are different methods of granulation such as wet granulation, dry granulation, and direct compression.

  • Examples of granulating agents include binders, disintegrants, and lubricants.

Q91. Full meaning in chemistry

Ans.

Full meaning in chemistry refers to the complete definition of a term or concept in the field of chemistry.

  • Full meaning in chemistry is the complete definition of a term or concept in the field of chemistry.

  • It is important to understand the full meaning of a term or concept in order to apply it correctly in experiments or research.

  • For example, the full meaning of pH is the negative logarithm of the hydrogen ion concentration in a solution.

  • Another example is the full meaning o...read more

Q92. RMG end point?

Ans.

RMG end point refers to the point at which the reaction mass is considered complete in a chemical production process.

  • RMG end point is determined by monitoring various parameters such as temperature, pressure, pH, or color change.

  • It indicates that the desired reaction has reached its completion and no further reaction is expected.

  • For example, in the production of a pharmaceutical drug, the RMG end point may be reached when the desired purity level is achieved.

  • Accurate determin...read more

Q93. What is SCDM ?

Ans.

SCDM stands for Study Data Tabulation Model, a standard for organizing and formatting clinical trial data.

  • SCDM is a standard format used in clinical research to structure and organize data collected during a clinical trial.

  • It helps ensure consistency and accuracy in data collection, analysis, and reporting.

  • SCDM includes guidelines for creating datasets, defining variables, and organizing data for submission to regulatory authorities.

  • Adhering to SCDM standards helps ensure dat...read more

Q94. What is pharmaceutis

Ans.

Pharmaceutics is the study of the process of turning a chemical substance into a medication.

  • Pharmaceutics involves the design, development, and formulation of drugs.

  • It also includes the study of drug delivery systems and drug stability.

  • Pharmaceutics plays a crucial role in ensuring the safety and efficacy of medications.

  • Examples of pharmaceutics include the development of new drug formulations and the study of drug interactions.

  • Pharmaceutics is closely related to pharmacology...read more

Q95. What is chemistry

Ans.

Chemistry is the study of matter, its properties, composition, and interactions.

  • Chemistry involves understanding the structure and behavior of atoms and molecules

  • It explores how substances react with each other to form new substances

  • Chemistry is used in various industries such as pharmaceuticals, agriculture, and manufacturing

Q96. Quality of hypo

Ans.

Quality of hypo is crucial for accurate and safe chemical production.

  • Hypo should be free from impurities and contaminants.

  • It should have a consistent concentration of active ingredients.

  • The pH level should be within the specified range.

  • The hypo should be stored properly to prevent degradation.

  • Regular testing and analysis should be conducted to ensure quality.

  • Examples of hypo include sodium thiosulfate and ammonium thiosulfate.

Q97. Types of reaction

Ans.

Types of reaction

  • Chemical reactions can be classified into several types based on the nature of reactants and products

  • Some common types of reactions include synthesis, decomposition, combustion, displacement, and redox reactions

  • Synthesis reactions combine two or more substances to form a new compound, e.g., A + B → AB

  • Decomposition reactions break down a compound into its constituent elements or simpler compounds, e.g., AB → A + B

  • Combustion reactions involve the rapid combinat...read more

Q98. Write strong acid

Ans.

A strong acid is a chemical compound that completely dissociates into ions in an aqueous solution.

  • Strong acids have a low pH value, typically less than 2.

  • They are highly corrosive and can cause severe burns.

  • Examples of strong acids include hydrochloric acid (HCl), sulfuric acid (H2SO4), and nitric acid (HNO3).

Q99. Excipient used in tablet

Ans.

Excipients are inactive substances added to a drug to help with the manufacturing process, stability, or appearance of the tablet.

  • Excipients can include fillers, binders, disintegrants, lubricants, and coloring agents.

  • Examples of excipients used in tablets are microcrystalline cellulose, lactose, magnesium stearate, and titanium dioxide.

Q100. Procedure of anfd

Ans.

ANFD stands for Agitated Nutsche Filter Dryer, a type of equipment used in chemical processing for filtration, washing, and drying of solids.

  • ANFD is used for separating solids from liquids in a slurry mixture.

  • The equipment consists of a cylindrical vessel with an agitator, filter media, and a vacuum system.

  • The slurry is agitated to aid in filtration, then the solids are washed and dried using the vacuum system.

  • ANFD is commonly used in pharmaceutical, chemical, and food indust...read more

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