Drug Safety Physician

Drug Safety Physician Interview Questions and Answers

Updated 14 Jun 2024

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Q1. What is PV in my own language and not bookish definition, MEdDRA, Triage, AE outcome

Ans.

PV stands for Pharmacovigilance, which is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems.

PV is the process of monitoring and evaluating the safety of drugs or medical products.
It involves collecting and analyzing data on adverse drug reactions (ADRs) and other drug-related problems.
PV aims to identify and minimize risks associated with the use of drugs.
It plays a crucial role...read more

Q2. WHAT ARE ANTIMICROBIAL DRUGS AND ITS MECHANISM

Ans.

Antimicrobial drugs are medications used to treat infections caused by bacteria, fungi, viruses, or parasites.

Antimicrobial drugs target specific components of microorganisms to inhibit their growth or kill them.
Examples include antibiotics (e.g. penicillin), antifungals (e.g. fluconazole), antivirals (e.g. acyclovir), and antiparasitics (e.g. metronidazole).
Mechanisms of action include disrupting cell wall synthesis, inhibiting protein synthesis, interfering with DNA replica...read more

Drug Safety Physician Interview Questions and Answers for Freshers

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Q3. What is meant by half life of the drug?

Ans.

Half life of a drug is the time it takes for the concentration of the drug in the body to be reduced by half.

Half life is a pharmacokinetic parameter used to determine the rate at which a drug is eliminated from the body.
It helps in determining the dosing frequency of a drug - drugs with longer half-lives may be dosed less frequently.
Half life is influenced by factors such as metabolism, excretion, and distribution of the drug in the body.
For example, the half life of aspirin...read more

Q4. WHAT ARE THE DRUGS USED IN MI.

Ans.

Drugs used in myocardial infarction (MI) include antiplatelet agents, beta blockers, ACE inhibitors, and statins.

Antiplatelet agents such as aspirin and clopidogrel are used to prevent blood clots
Beta blockers like metoprolol help reduce heart rate and blood pressure
ACE inhibitors like lisinopril help improve heart function and reduce strain on the heart
Statins like atorvastatin are used to lower cholesterol levels and reduce the risk of further heart problems

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Q5. What is adverse drug reactions

Ans.

Adverse drug reactions are harmful or unintended reactions to medications.

Adverse drug reactions are unwanted effects caused by a medication.
They can range from mild side effects to severe reactions.
Examples include nausea, dizziness, allergic reactions, and liver damage.
Monitoring and reporting adverse drug reactions is important for patient safety.

Q6. Types of adverse drug reaction

Ans.

Adverse drug reactions can be classified into six types.

Type A: Augmented pharmacological effects
Type B: Bizarre effects
Type C: Chronic effects
Type D: Delayed effects
Type E: End-of-treatment effects
Type F: Failure of therapy

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Q7. 4 types

Ans.

There are 4 types of drug interactions: pharmacokinetic, pharmacodynamic, combined toxicity, and additive effects.

Pharmacokinetic interactions affect the way a drug is absorbed, distributed, metabolized, or excreted.
Pharmacodynamic interactions occur when two drugs with similar or opposing effects are taken together.
Combined toxicity interactions happen when two drugs with toxic effects are taken together, resulting in a greater toxicity.
Additive effects occur when two drugs ...read more