Research Associate - CAR-T Upstream Manufacturing

• M.Sc/M.Tech in Biotechnology with 2-7 years of relevant experience in academia and/or industry
• Hands-on experience in developing, manufacturing, and characterizing CAR cell therapy products is preferred. In depth understanding of Cell Therapy Research and associated regulatory guidelines

Roles & Responsibilities:

• Responsible for optimization of CAR cells manufacturing processes using normal human or patient derived primary blood components, following ethical practices and QMS as per GMP guidelines
• Actively engage in the manufacture of CAR-T cell therapy products by diligently prioritizing the lab functions to meet critical deadlines.
• Establish and carefully execute transduction by viral vector and non-viral vector-based approaches, activation, and expansion of immune cells (T cells, NK cells, etc) isolated from clinical specimens without compromising sterility and quality parameters as per the guidelines and defined criteria by maintaining highest standards.
• Able to communicate effectively in a highly matrixed team environment to advance the company's cell therapy pipeline
• Participate and assist in technical transfer and core R&D activities To review and document SOPs, protocols and reports pertaining to the program requirements.
• Work closely with cross-functional teams to design and implement cell therapy processes and workflow for cell therapy platforms
• Provide critical technical/scientific recommendations for the manufacturing process improvements
• Work with vendors to evaluate raw materials and consumables for compatibility with the Manufacturing process