100+ PwC Interview Questions and Answers

NMR of xylene is a technique used to study the chemical structure and properties of xylene.

• NMR stands for Nuclear Magnetic Resonance

• It is a spectroscopic technique that uses the magnetic properties of atomic nuclei to determine the physical and chemical properties of molecules

• NMR of xylene can provide information about the number and types of atoms in the molecule, as well as their arrangement and chemical environment

• It can also be used to study the purity and concentration o...read more

Equipment qualification process ensures that equipment is suitable for its intended use by following a systematic approach.

• Define equipment requirements and specifications

• Select appropriate equipment based on requirements

• Install and set up equipment according to manufacturer's guidelines

• Perform operational and performance qualification tests

• Document all qualification activities and results

Calibration of instruments is a process of adjusting and verifying the accuracy of measurements made by the instrument.

• Calibration involves comparing the readings of the instrument to known standards.

• It is important to calibrate instruments regularly to ensure accurate results.

• Calibration certificates should be kept as proof of calibration.

• Examples of instruments that require calibration include thermometers, pressure gauges, and pH meters.

Reconciliation is the process of comparing two sets of records to ensure they are in agreement.

• Gather all relevant records and documents

• Compare the records to identify any discrepancies

• Investigate and resolve any discrepancies found

• Document the reconciliation process and any adjustments made

• Perform regular reconciliations to ensure accuracy

Dissolution refers to the process of dissolving a solid substance in a liquid to form a homogeneous solution.

• It is an important parameter in drug development and quality control

• It determines the rate and extent of drug absorption in the body

• Factors affecting dissolution include particle size, solubility, pH, and temperature

• Dissolution testing is performed using various apparatus such as USP apparatus 1, 2, 3, and 4

• Examples of drugs with poor dissolution include carbamazepine ...read more

Method validation for Assay by HPLC involves testing the accuracy, precision, specificity, and linearity of the method.

• The method should be tested for accuracy by comparing the results obtained with a reference standard or method.

• Precision can be determined by analyzing multiple samples and calculating the standard deviation.

• Specificity can be tested by analyzing samples with known interferences and ensuring they do not interfere with the assay.

• Linearity can be determined by ...read more

Tablets are solid dosage forms of medication that are compressed into a small, round, or oval shape for easy swallowing.

• Tablets can be classified based on their release mechanism (immediate release, extended release, etc.)

• They can also be categorized by their route of administration (oral, sublingual, buccal, etc.)

• Examples include paracetamol tablets, ibuprofen tablets, and vitamin C tablets.

Capsules are pharmaceutical dosage forms in which the drug is enclosed in a gelatin shell.

• Capsules are made up of two main types: hard capsules and soft capsules.

• Hard capsules are typically used for solid drugs and are made of two pieces that fit together.

• Soft capsules are used for liquid or semi-solid drugs and have a single-piece gelatin shell.

• There are also specialized capsules like enteric-coated capsules and sustained-release capsules.

• Enteric-coated capsules have a speci...read more

I handle a variety of production equipment including machinery, tools, and instruments.

• Operate and maintain production machinery such as conveyor belts, mixers, and packaging machines

• Use hand tools like wrenches, screwdrivers, and drills for assembly and repairs

• Calibrate and monitor instruments like thermometers, pressure gauges, and pH meters

• Ensure proper functioning of equipment to meet production targets and quality standards

Acetaminophen is a common over-the-counter pain reliever and fever reducer.

• Acetaminophen is also known as paracetamol.

• It is commonly used to treat headaches, muscle aches, arthritis, backaches, toothaches, colds, and fevers.

• It is often found in medications like Tylenol, Excedrin, and NyQuil.

Variation guidelines are regulatory requirements for making changes to a product's marketing authorization.

• Variation guidelines outline the procedures and documentation required for submitting changes to a product's marketing authorization.

• Changes can include modifications to the manufacturing process, formulation, packaging, labeling, or indications for use.

• Variation guidelines help ensure that changes do not compromise the safety, efficacy, or quality of the product.

• Regulat...read more

DC's are direct current power sources while PLCs are programmable logic controllers used for automation.

• DC's provide constant voltage and current flow in one direction, used in simple circuits.

• PLCs are digital computers used to control machinery and processes, programmed using ladder logic or other languages.

• DC's are typically used for power supply in electronic devices, while PLCs are used for automation in industrial settings.

• DC's are simpler and more basic compared to the ...read more

Molarity is a measure of the concentration of a solute in a solution, expressed as the number of moles of solute per liter of solution.

• Molarity is calculated by dividing the number of moles of solute by the volume of the solution in liters.

• It is commonly denoted by the symbol 'M'.

• For example, a 1M solution of sodium chloride contains 1 mole of sodium chloride dissolved in 1 liter of water.

Form 29 is a document used in project management to request changes to the project scope, schedule, or budget.

• Form 29 is typically used to document and track changes requested by stakeholders.

• It includes details such as the reason for the change, impact on project objectives, and proposed solution.

• The form may require approval from project sponsors or steering committee before implementation.

Procure to pay cycle involves all steps from identifying a need for a product or service to making the payment for it.

• Identifying the need for a product or service

• Requesting quotes or proposals from suppliers

• Selecting a supplier and negotiating terms

• Creating a purchase order

• Receiving the goods or services

• Matching the invoice with the purchase order and goods receipt

• Approving the invoice for payment

• Making the payment to the supplier

Top 10 anti-cancer drugs include chemotherapy agents, targeted therapies, and immunotherapy drugs.

• Chemotherapy agents: such as paclitaxel, doxorubicin, and cisplatin

• Targeted therapies: such as trastuzumab, imatinib, and vemurafenib

• Immunotherapy drugs: such as pembrolizumab, nivolumab, and ipilimumab

The latest drug invention is a groundbreaking treatment for Alzheimer's disease.

• The drug targets the build-up of amyloid plaques in the brain, a hallmark of Alzheimer's disease.

• Clinical trials have shown promising results in slowing down cognitive decline in patients.

• The drug is expected to receive FDA approval in the near future.

• Researchers are also exploring combination therapies to enhance the drug's effectiveness.

Normality refers to the state of being within the typical or expected range of behavior or characteristics.

• Normality is often used in statistics to describe data that follows a bell-shaped curve, with the majority of values clustered around the mean.

• In chemistry, normality is a measure of concentration, specifically the number of equivalents of a substance per liter of solution.

• In psychology, normality can refer to behavior that is considered typical or healthy within a certa...read more

Density is a measure of how much mass is contained in a given volume.

• Density is calculated by dividing the mass of an object by its volume.

• It is commonly expressed in units such as grams per cubic centimeter (g/cm^3) or kilograms per liter (kg/L).

• Objects with higher density have more mass packed into a smaller volume, while objects with lower density have less mass in a larger volume.

• For example, lead has a higher density than feathers because a given volume of lead is much h...read more

I have previous experience working as a Junior Officer in a government agency.

• Managed administrative tasks such as filing, data entry, and document preparation

• Assisted in organizing and coordinating meetings and events

• Handled correspondence and communication with internal and external stakeholders

• Contributed to the development and implementation of policies and procedures

• Supported senior officers in various projects and initiatives

Operation of utility equipment involves understanding the functionality and maintenance of various systems to ensure smooth operation.

• Understanding the purpose and function of each utility equipment

• Regular maintenance and inspection to prevent breakdowns

• Following safety protocols and guidelines while operating equipment

• Troubleshooting and resolving issues efficiently

• Training team members on proper operation and maintenance practices

As a Senior Research Scientist, I have performed various analytical activities such as data analysis, statistical modeling, and experimental design.

• Conducted data analysis using statistical software like R and Python

• Developed statistical models to analyze experimental data

• Designed experiments to test hypotheses and validate results

• Performed quality control analysis to ensure accuracy of results

• Collaborated with cross-functional teams to interpret and communicate findings

Centrifuge is a machine that separates components of a mixture based on their density using centrifugal force.

• Centrifuge works by spinning a container at high speed, causing the denser components to move towards the bottom of the container.

• The separated components can then be collected from different layers of the container.

• Centrifuges are used in various fields such as medical, scientific research, and industrial applications.

• Examples of centrifuges include blood centrifuges...read more

HEPA filter is a type of air filter that can trap a large number of very small particles that other vacuum cleaners would simply recirculate back into the air of your home.

• HEPA stands for High Efficiency Particulate Air

• It can capture particles as small as 0.3 microns with 99.97% efficiency

• Commonly used in air purifiers, vacuum cleaners, and HVAC systems

• Helps improve indoor air quality by trapping allergens, dust, and other pollutants

AE stands for Adverse Event and SAE stands for Serious Adverse Event.

• AE refers to any unexpected or unfavorable medical occurrence in a patient or clinical trial participant, regardless of whether it is related to the treatment being studied.

• SAE refers to any adverse event that results in death, is life-threatening, requires hospitalization or prolongation of existing hospitalization, results in persistent or significant disability or incapacity, or is a congenital anomaly or...read more

SN1 reaction is a type of nucleophilic substitution reaction where the rate-determining step involves the formation of a carbocation intermediate.

• SN1 stands for substitution nucleophilic unimolecular

• It involves a two-step mechanism

• The first step is the formation of a carbocation intermediate

• The second step is the attack of a nucleophile on the carbocation

• It is a common reaction for tertiary alkyl halides

• Examples include the reaction of tert-butyl chloride with water to form t...read more

The working principle of mcdp involves analyzing and optimizing the flow of data in a network.

• MCDP stands for Maximum Concurrent Data Paths.

• It is a method used in networking to optimize data flow by analyzing the number of concurrent data paths that can be processed efficiently.

• By understanding the maximum number of data paths that can be handled simultaneously, network performance can be improved.

• MCDP helps in identifying bottlenecks and optimizing data transmission in a net...read more

A Star Delta connection is a type of starting method for 3-phase AC induction motors.

• Star Delta connection is used to reduce starting current and torque in induction motors.

• In Star Delta connection, the motor is initially connected in star configuration for starting and then switched to delta configuration for running.

• This method is commonly used in industrial applications where high starting torque is required.

• The wiring diagram for a Star Delta connection typically includes...read more

A tablet is a solid dosage form of medication that is compressed into a small, round or oval shape for easy swallowing.

• Tablets are one of the most common forms of medication used for oral administration.

• They are made by compressing a mixture of active pharmaceutical ingredients and excipients into a solid form.

• Tablets can come in various shapes, sizes, and colors depending on the medication and manufacturer.

• Examples include aspirin tablets, vitamin tablets, and antibiotic tab...read more

My browser options include Chrome, Firefox, Safari, and Edge.

• Chrome

• Firefox

• Safari

• Edge

My future goal in life is to become a respected leader in the field of mechanical engineering, contributing to innovative projects and mentoring the next generation of engineers.

• Continuously improve my technical skills and knowledge through advanced training and certifications

• Lead and successfully execute complex engineering projects from concept to completion

• Mentor and guide junior engineers to help them grow and succeed in their careers

• Contribute to the development of cutti...read more

HPLC (High-Performance Liquid Chromatography) is a technique for separating, identifying, and quantifying components in a mixture.

• HPLC uses high pressure to push solvents through a column packed with stationary phase material.

• Commonly used in pharmaceuticals for drug analysis and purity testing.

• Different types of HPLC include normal phase, reverse phase, and size exclusion chromatography.

• Applications extend to environmental testing, food safety, and biochemical analysis.

• Examp...read more

ETP operating work involves monitoring and maintaining the equipment to treat wastewater before it is discharged.

• Monitor ETP equipment to ensure proper functioning

• Adjust chemical dosages as needed for effective treatment

• Perform regular maintenance on ETP system

• Keep records of water quality parameters and treatment processes

• Troubleshoot any issues that arise during operation