Lee Pharma R&D Chemist Interview Questions and Answers

The challenge test of a machine is a test to determine its capabilities and limitations.

• The challenge test should be designed to push the machine to its limits.

• It should be conducted in a controlled environment to ensure safety.

• Examples of challenge tests include stress tests, endurance tests, and performance tests.

• The results of the challenge test can be used to improve the machine's design and performance.

FFS machine stands for Form-Fill-Seal machine, which is a packaging machine used to form, fill, and seal products in various industries.

• FFS machine is commonly used in industries such as food and beverage, pharmaceuticals, and cosmetics.

• It is an automated machine that can produce packaging materials on-site.

• The machine forms a package from a flat roll of film, fills it with the product, and then seals it.

• FFS machines c...read more

Kaizen is a Japanese term for continuous improvement. It involves making small, incremental changes to improve processes and systems.

• Kaizen is a philosophy that focuses on continuous improvement in all aspects of an organization.

• It involves identifying areas for improvement, making small changes, and then evaluating the results.

• Kaizen can be applied to any process or system, from manufacturing to healthcare.

• Examples of...read more

Transformers are electrical devices that transfer energy between two or more circuits through electromagnetic induction.

• Transformers are used to increase or decrease voltage levels in electrical circuits

• They consist of two coils of wire wrapped around a magnetic core

• The primary coil is connected to the input voltage and the secondary coil to the output load

• Step-up transformers increase voltage while step-down transform...read more

Water content mechanism can be found through various methods and is important for various reasons.

• Water content can be measured through techniques such as gravimetric analysis, Karl Fischer titration, and moisture analyzers.

• Water content is important in industries such as food, pharmaceuticals, and cosmetics to ensure product quality and stability.

• Water content is also important in environmental studies to understand t...read more

Developing HPLC methods involves selecting appropriate columns and optimizing parameters.

• Choose a suitable column based on the analyte's properties and the separation goal.

• Optimize parameters such as mobile phase composition, flow rate, and temperature.

• Validate the method by assessing its selectivity, sensitivity, accuracy, and precision.

• Common column types include C18, C8, and phenyl.

• Other factors to consider include ...read more

Carbon loading in column refers to the amount of carbon used in the stationary phase of a chromatography column. Endcapping is a process to block the remaining silanol groups on the surface of the stationary phase.

• Carbon loading is typically expressed as a percentage of the total weight of the stationary phase.

• Higher carbon loading can improve the selectivity and retention of certain analytes.

• Endcapping is important to...read more

SAP activity refers to the use of SAP software for business operations and management.

• SAP activity involves using SAP software for various business functions such as finance, human resources, supply chain management, and customer relationship management.

• It helps organizations streamline their processes, improve efficiency, and make data-driven decisions.

• Examples of SAP activity include creating financial reports, manag...read more

pH activity refers to the measurement of acidity or alkalinity of a solution.

• pH activity is measured on a scale of 0-14, with 7 being neutral, below 7 being acidic, and above 7 being alkaline

• It is important in various fields such as chemistry, biology, and environmental science

• For example, pH activity is used to determine the acidity of soil for agriculture, the pH of water for aquatic life, and the pH of blood for med

The pH value decreases when acid is added and increases when alkali is added.

• Acids release hydrogen ions (H+) when dissolved in water, which increases the concentration of H+ ions and lowers the pH value.

• Alkalis release hydroxide ions (OH-) when dissolved in water, which decreases the concentration of H+ ions and raises the pH value.

• The pH scale ranges from 0 to 14, with 7 being neutral. Values below 7 are acidic, and ...read more

Chemical reaction between sodium and chlorine

• Sodium (Na) reacts with chlorine (Cl) to form sodium chloride (NaCl)

• The reaction is exothermic and releases energy in the form of heat and light

• The balanced chemical equation is 2Na + Cl2 -> 2NaCl