Biocon Limited IT Infrastructure Manager Interview Questions and Answers

Q1. Factor affecting the lyophilization
Ans. 
Factors affecting lyophilization
• Temperature: The temperature during the lyophilization process affects the rate of sublimation and drying.

• Pressure: The pressure inside the lyophilizer chamber affects the rate of sublimation and drying.

• Product formulation: The composition and concentration of the product being lyophilized can impact the process.

• Freezing method: The method used to freeze the product prior to lyophilizati...read more
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Q2. What is the meaning of Triple point
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The triple point is the temperature and pressure at which all three phases of a substance (solid, liquid, and gas) coexist in equilibrium.
• The triple point is a unique combination of temperature and pressure for a substance.

• At the triple point, the solid, liquid, and gas phases of the substance can coexist in equilibrium.

• It is the point on a phase diagram where all three phases meet.

• The triple point is a fixed point use...read more
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Q3. Validation of lyophilizer
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Validation of lyophilizer involves testing and documentation to ensure its performance and reliability.
• Validation of lyophilizer is necessary to ensure that it consistently produces high-quality freeze-dried products.

• The process involves testing various parameters such as temperature, pressure, and drying time to ensure they meet predetermined specifications.

• Documentation of the validation process is crucial for regula...read more
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Q4. How to maintain HSO in lyophilized product
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Maintaining HSO in lyophilized product involves proper storage conditions and packaging.
• Store the lyophilized product in a cool and dry environment to prevent moisture absorption.

• Use appropriate packaging materials that provide a barrier against moisture and oxygen.

• Ensure the lyophilized product is sealed tightly to prevent any exposure to air.

• Consider using desiccants or moisture-absorbing packets in the packaging.

• Per...read more
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Q1. About Job Profile
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Q1. About experience
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Q1. Negotiation of salary
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Basic aptitude test to check IQ level

Q1. Technical interview based on your experience
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Q1. Basic introduction
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Q2. Questions regarding what projects or case study have you done in past
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Q1. Personal details
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Q2. Family background
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Q3. Family background information
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Q4. Past experience
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Q1. They will verify deep , technical knowledge
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Q2. Pure technical questions in pharma Quality
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Q1. HR round will be for salary discussions
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Q1. Self introduction
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Q2. Drug product development
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