10+ Apitoria Pharma Interview Questions and Answers

The principal UV-visible spectrophotometer is a scientific instrument used to measure the absorption of light by a sample in the ultraviolet and visible regions of the electromagnetic spectrum.

• UV-visible spectrophotometers are commonly used in analytical chemistry, biochemistry, and pharmaceutical industries.

• They are used to determine the concentration of a sample by measuring how much light it absorbs at different wavelengths.

• Examples of popular UV-visible spectrophotometers...read more

Data backup involves regularly saving copies of data to prevent loss, while analytical data review is the process of examining and interpreting data for insights.

• Data backup involves creating duplicate copies of data to ensure it is not lost in case of system failure or other issues.

• Analytical data review includes examining data sets to identify trends, patterns, and insights that can inform decision-making.

• Regularly scheduled backups should be performed to ensure data is up-...read more

A polarimeter is a scientific instrument used to measure the angle of rotation of polarized light as it passes through a substance.

• Polarimeters are commonly used in chemistry to determine the concentration and purity of optically active substances.

• The principle of a polarimeter is based on the ability of chiral molecules to rotate the plane of polarized light.

• The angle of rotation is measured using a polarizer, a polarized light source, and a detector.

• The specific rotation of...read more

cGMP stands for current Good Manufacturing Practice, which are regulations enforced by the FDA to ensure quality in pharmaceutical production. MR meter calibration is the process of ensuring accuracy in measuring devices.

• cGMP is a set of regulations enforced by the FDA to ensure quality in pharmaceutical manufacturing

• MR meter calibration is the process of adjusting and verifying the accuracy of measuring devices like MR meters

• Both cGMP and MR meter calibration are important i...read more

KF R factor analysis is performed by calculating the ratio of the observed variance to the expected variance in a factor analysis model.

• Calculate the ratio of the observed variance to the expected variance for each factor in the factor analysis model.

• The KF R factor analysis helps in determining the goodness of fit of the factor model.

• Higher KF R values indicate a better fit between the observed data and the factor model.

Manpower can be requited by offering competitive salaries, providing opportunities for growth and development, creating a positive work environment, and recognizing and rewarding employees' contributions.

• Offer competitive salaries to attract and retain top talent

• Provide opportunities for growth and development through training programs and career advancement

• Create a positive work environment with open communication, teamwork, and a healthy work-life balance

• Recognize and rewar...read more

OOS investigation flow involves identifying, investigating, and resolving deviations from specifications.

• Identify the OOS result through testing or monitoring

• Investigate the root cause of the deviation

• Implement corrective actions to prevent recurrence

• Document the investigation process and findings

• Review and approve the investigation report

The vacuum build in Hyderabad varies depending on the location and time of measurement.

• Vacuum levels in Hyderabad can range from 700 to 760 mmHg

• Factors such as altitude, weather conditions, and equipment used can affect vacuum levels

• For example, in a laboratory setting, a vacuum pump may be used to create a vacuum for experiments

To open a vacuum tray dryer, follow these steps carefully.

• Ensure the vacuum tray dryer is turned off and disconnected from power source.

• Release any pressure inside the dryer by slowly opening the vent valve.

• Unlock and open the door of the vacuum tray dryer.

• Carefully remove the trays one by one, starting from the top.

• Inspect the trays for any residue or product buildup and clean if necessary.

• Close the door securely after removing or loading trays.

• Reconnect the power source and...read more

Measures involved in process development of an API include optimization of synthetic route, selection of raw materials, purification techniques, and analytical method development.

• Optimization of synthetic route to improve yield and reduce impurities

• Selection of high-quality raw materials to ensure consistency and purity of the final product

• Development of purification techniques such as crystallization, distillation, or chromatography

• Analytical method development for testing t...read more

Reactors are operated by following standard operating procedures, monitoring key parameters, adjusting conditions as needed, and ensuring safety protocols are followed.

• Follow standard operating procedures provided by the manufacturer or company

• Monitor key parameters such as temperature, pressure, flow rate, and pH regularly

• Adjust conditions as needed to maintain desired reaction conditions

• Ensure safety protocols are followed at all times to prevent accidents

• Keep detailed reco...read more

An exothermic reaction is a chemical reaction that releases energy in the form of heat.

• Exothermic reactions release heat to the surroundings

• They have a negative change in enthalpy (ΔH)

• Examples include combustion reactions, neutralization reactions, and some oxidation reactions

A clean room is a controlled environment with low levels of pollutants such as dust, airborne microbes, aerosol particles, and chemical vapors.

• Clean rooms are typically used in industries such as pharmaceuticals, biotechnology, electronics, and aerospace.

• They are designed to maintain a specific level of cleanliness to ensure the quality of products being manufactured.

• Clean rooms have strict protocols for entry, including wearing special clothing like gowns, gloves, masks, and...read more

Daily work plan involves setting goals, prioritizing tasks, analyzing data, and implementing improvements.

• Create a daily work plan outlining tasks and goals

• Prioritize tasks based on importance and deadlines

• Analyze data collected from quality control processes

• Identify areas for improvement and implement changes

• Review and adjust work plan as needed

Improving quality involves setting clear standards, continuous monitoring, feedback loops, and employee training.

• Establish clear quality standards and guidelines

• Implement regular quality checks and audits

• Encourage feedback from customers and employees

• Provide training and development opportunities for employees to enhance skills and knowledge